NRIP2 - nuclear receptor interacting protein 2 Gene

Homo sapiens

Gene ID: 83714 | Gene type: protein coding

About NRIP2

This gene has 3 transcripts (splice variants), 174 orthologues and 4 paralogues. Ubiquitous expression in kidney (RPKM 4.3), ovary (RPKM 4.3) and 25 other tissues.

Summary

Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NRIP2 Products(1)

mRNA	Protein	Name
NM_031474.3	NP_113662.1	nuclear receptor-interacting protein 2

NRIP2 Protein Structure

Asp_protease

0
100
200
281 a.a.

Protein Preferred Names

Protein Names

nuclear receptor-interacting protein 2

Related Diseases

Diseases

Alias

Temtamy Syndrome

TEMTYS	Craniofacial Dysmorphism With Ocular Coloboma Absent Corpus Callosum And Aortic Dilatation
Craniofacial Dysmorphism-Coloboma-Corpus Callosum Agenesis Syndrome	Dysmorphism, Corpus Callosum Agenesis And Colobomas
Temtamy-Shalash Syndrome	Mental Retardation With Or Without Craniofacial Dysmorphism, Ocular Coloboma, Or Abnormal Corpus Callosum

Sneddon Syndrome

Livedo Reticularis And Cerebrovascular Accidents	SNDNS
Ehrmann-Sneddon Syndrome	Livedo Racemosa-Cerebrovascular Accident Syndrome
Livedo Reticularis-Cerebrovascular Accident Syndrome	Sneddon'S Syndrome
Idiopathic Livedo Reticularis With Systemic Involvement	Cerebro-Vascular Lesions And Livedo Reticularis
Livedo Racemosa And Cerebrovascular Accidents

Cantu Syndrome

Hypertrichotic Osteochondrodysplasia	Hypertrichotic Osteochondrodysplasia Cantu Type
Cantú Syndrome	Craniofaciocardioskeletal Syndrome
Hypertrichosis-Osteochondrodysplasia-Cardiomegaly Syndrome	Congenital Hypertrichosis-Acromegaloid Facial Features Spectrum
Congenital Hypertrichosis-Coarse Facial Features Spectrum	HTOCD
Osteochondrodysplasia, Hypertrichotic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09572	NRIP2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	NRIP2	RGD	RGD:1589959
Felis catus	NRIP2	VGNC	VGNC:63879
Bos taurus	NRIP2	VGNC	VGNC:59356
Macaca mulatta	NRIP2	VGNC	VGNC:75448
Mus musculus	NRIP2	MGD	MGI:1891884
Canis familiaris	NRIP2	VGNC	VGNC:43970

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