MT4 - metallothionein 4 Gene

Homo sapiens

Also known as MT-4; MTIV; MT-IV

Gene ID: 84560 | Gene type: protein coding

About MT4

Cytogenetic location: 16q13 Genomic coordinates (GRCh38): 16:56,565,073-56,568,957 (from NCBI)

This gene has 1 transcript (splice variant), 166 orthologues and 11 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in cellular response to metal ion; cellular zinc ion homeostasis; and detoxification of copper ion. Predicted to act upstream of or within cellular metal ion homeostasis. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MT4 Products(1)

mRNA	Protein	Name
NM_032935.3	NP_116324.2	metallothionein-4

MT4 Protein Structure

Metallothio

0
62 a.a.

Protein Preferred Names

Protein Names

metallothionein-4

metallothionein-IV

Related Diseases

Diseases

Alias

Cortical Thymoma

Polygonal Cell Thymoma	Thymoma, Cortical
Thymoma, Type B2

Deficiency Anemia

Anemia	Deficiency Anemias
Anaemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Phase
HY-111964	Lenacapavir	Inhibitor	98.48%	Phase 3
HY-50101A	Mavorixafor trihydrochloride		98.69%	Phase 3
HY-50101	Mavorixafor		/	Phase 3

Pre-clinical Phase

Bioactive Molecules (26)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15355	Loviride	Inhibitor	99.59%	Unkown
HY-135856	SARS-CoV-IN-2	Inhibitor	98.66%	Unkown
HY-135858	SARS-CoV-IN-3	Inhibitor	99.36%	Unkown
HY-128595	MT-4		98.85%	Unkown
HY-137309	4-Deoxy-4α-phorbol		/	Unkown
HY-146090	HIV-1 inhibitor-33	Inhibitor	/	Unkown
HY-10891	HIV-1 inhibitor-61	Inhibitor	/	Unkown
HY-122229	GS-9822	Inhibitor	/	Unkown
HY-125810	4'-Ethynyl-2'-deoxyadenosine	Inhibitor	/	Unkown
HY-144714	HIV-1 inhibitor-18	Inhibitor	/	Unkown
HY-144715	HIV-1 inhibitor-17	Inhibitor	/	Unkown
HY-146015	HIV-1 inhibitor-21	Inhibitor	/	Unkown
HY-146019	HIV-1 inhibitor-24	Inhibitor	/	Unkown
HY-146019A	HIV-1 inhibitor-25	Inhibitor	/	Unkown
HY-146091	HIV-1 inhibitor-34	Inhibitor	/	Unkown
HY-146352	HIV-1 inhibitor-28	Inhibitor	/	Unkown
HY-146353	HIV-1 inhibitor-29	Inhibitor	/	Unkown
HY-147723	HIV-1 inhibitor-39	Inhibitor	/	Unkown
HY-149866	HIV-1 inhibitor-58	Inhibitor	/	Unkown
HY-152539	HIV-1 inhibitor-54	Inhibitor	/	Unkown
HY-153583	HDAC8-IN-4	Inhibitor	/	Unkown
HY-N12678	Daphnepedunin A	Inhibitor	/	Unkown
HY-RS08745	MT4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-50101C	Mavorixafor hydrochloride		/	Unkown
HY-N11288	Methyl salvionolate A	Inhibitor	/	Unkown
HY-18666	D77	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	MT4	VGNC	VGNC:31713
Macaca mulatta	MT4	VGNC	VGNC:99525
Canis familiaris	MT4	VGNC	VGNC:52145
Rattus norvegicus	MT4	RGD	RGD:1565500
Mus musculus	MT4	MGD	MGI:99692
Others	MT4	NCBI

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