SERPINB12 - serpin family B member 12 Gene

Homo sapiens

Also known as YUKOPIN

Gene ID: 89777 | Gene type: protein coding

About SERPINB12

Cytogenetic location: 18q21.33 Genomic coordinates (GRCh38): 18:63,519,110-63,569,329 (from NCBI)

This gene has 3 transcripts (splice variants), 90 orthologues and 36 paralogues. Restricted expression toward skin (RPKM 27.9).

Summary

Enables serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Part of collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

SERPINB12 Products(2)

mRNA	Protein	Name
NM_001307928.2	NP_001294857.1	serpin B12 isoform 1
NM_080474.2	NP_536722.1	serpin B12 isoform 2

SERPINB12 Protein Structure

Serpin

0
100
200
300
405 a.a.

Protein Preferred Names

Protein Names

serpin B12

serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12

Recombinant SERPINB12 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71304	Serpin B12 Protein, Human (HEK293, His)	Q96P63-2 (M1-P425)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12708	SERPINB12 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SERPINB12	RGD	RGD:1566382
Felis catus	SERPINB12	VGNC	VGNC:80485
Macaca mulatta	SERPINB12	VGNC	VGNC:77231
Mus musculus	SERPINB12	MGD	MGI:1919119
Canis familiaris	SERPINB12	VGNC	VGNC:46028
Bos taurus	SERPINB12	VGNC	VGNC:34471
Others	SERPINB12	NCBI

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