CD5L - CD5 molecule like Gene

Homo sapiens

Also known as AIM; API6; CT-2; hAIM; PRO229; Spalpha; SP-ALPHA

Gene ID: 922 | Gene type: protein coding

About CD5L

Cytogenetic location: 1q23.1 Genomic coordinates (GRCh38): 1:157,827,068-157,841,808 (from NCBI)

This gene has 2 transcripts (splice variants), 371 orthologues and 15 paralogues. Restricted expression toward spleen (RPKM 260.3).

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Predicted to act upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022]

CD5L Products(2)

mRNA	Protein	Name
NM_001347698.2	NP_001334627.1	CD5 antigen-like isoform 2 precursor
NM_005894.3	NP_005885.1	CD5 antigen-like isoform 1 precursor

CD5L Protein Structure

SRCR

0
100
200
300
347 a.a.

Protein Preferred Names

Protein Names

CD5 antigen-like

CD5 antigen-like (scavenger receptor cysteine rich family)

Recombinant CD5L Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72718	CD5L Protein, Human (HEK293, His)	O43866 (S20-G347)	≥95%
HY-P75656	CD5L Protein, Human (347a.a, HEK293, His)	O43866 (M1-G347)	≥95%

Related Diseases

Diseases

Alias

Hereditary Elliptocytosis

Congenital Elliptocytosis	Ovalocytosis
Elliptocytosis, Hereditary	He
Elliptocytosis Hereditary	Congenital Ovalocytosis
Elliptocytosis	Hereditary Elliptocytosis With Infantile Poikilocytosis
Hereditary Ovalocytosis	Oval Erythrocytosis
He - [Hereditary Elliptocytosis]	Elliptocytosis Anaemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02258	CD5L Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CD5L	VGNC	VGNC:60634
Rattus norvegicus	CD5L	RGD	RGD:1308526
Mus musculus	CD5L	MGD	MGI:1334419
Canis familiaris	CD5L	VGNC	VGNC:38965
Bos taurus	CD5L	VGNC	VGNC:54903
Macaca mulatta	CD5L	VGNC	VGNC:70774
Others	CD5L	NCBI