Mgat2 - alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Gene

Rattus norvegicus

Also known as Gnt2

Gene ID: 94273 | Gene type: protein coding

About Mgat2

Primary_assembly 6: 87,656,349-87,658,177 forward strand.mRatBN7.2:CM026979.1

This gene has 1 transcript (splice variant), 178 orthologues and is associated with 10 phenotypes.

Summary

Enables alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity and carbohydrate binding activity. Involved in protein N-linked glycosylation. Predicted to be located in Golgi apparatus and cytoplasmic side of rough endoplasmic reticulum membrane. Predicted to be part of large ribosomal subunit. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIa. Orthologous to human MGAT2 (alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mgat2 Products(1)

mRNA	Protein	Name
NM_053604.2	NP_446056.1	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

Mgat2 Protein Structure

MGAT2

0
100
200
300
400
442 a.a.

Protein Preferred Names

Protein Names

alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

GNT-II	N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II
beta-1,2-N-acetylglucosaminyltransferase II	beta-12-N-acetylglucosaminyltransferase II
glcNAc-T II	mannoside acetylglucosaminyltransferase 2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-U00430	MGAT2-IN-2	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mgat2	NCBI	NCBI:4247