2. Gene
  3. ACAP1 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 Gene

ACAP1 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CENTB1

Gene ID: 9744 | Gene type: protein coding

About ACAP1

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,336,529-7,351,477 (from NCBI)

This gene has 12 transcripts (splice variants), 1 gene allele, 187 orthologues and 28 paralogues. Broad expression in lymph node (RPKM 20.4), spleen (RPKM 16.9) and 24 other tissues.

Summary

Predicted to enable GTPase activator activity and metal ion binding activity. Predicted to be involved in protein transport and regulation of catalytic activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

ACAP1 Products(1)

mRNA Protein Name
NM_014716.4 NP_055531.1 arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

ACAP1 Protein Structure

PH

PH: PH domain (267 - 359)

ArfGap

ArfGap: Putative GTPase activating protein for Arf (407 - 521)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (592 - 670)

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  • 600
  • 740 a.a.
Protein Preferred Names Protein Names

arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

Arf GAP with coiled coil, ANK repeat and PH domains 1

Related Diseases

Diseases Alias
Myoclonic Epilepsy, Juvenile 3

Myoclonic Epilepsy, Juvenile, Susceptibility To, 3

EJM3

Epilepsy, Juvenile Myoclonic 3

Juvenile Myoclonic Epilepsy 3
Benign Ileal Neoplasm

Ileal Tumor

Ileal Neoplasms

Ileal Neoplasm
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00133 ACAP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ACAP1 MGD MGI:2388270
Canis familiaris ACAP1 VGNC VGNC:37496
Rattus norvegicus ACAP1 RGD RGD:1305360
Bos taurus ACAP1 VGNC VGNC:25526
Felis catus ACAP1 VGNC VGNC:59497
Macaca mulatta ACAP1 VGNC VGNC:69427