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Glycidamide  (Synonyms: Oxiranecarboxamide; 2,3-Epoxypropanamide)

Cat. No.: HY-119329 Purity: ≥97.0%
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Glycidamide is the genotoxic metabolite of Acrylamide. Glycidamide can react with proteins, such as hemoglobin, or with DNA, and induces genotoxic effects.

For research use only. We do not sell to patients.

Glycidamide Chemical Structure

Glycidamide Chemical Structure

CAS No. : 5694-00-8

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5 mg USD 110 In-stock
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Based on 1 publication(s) in Google Scholar

Glycidamide Related Antibodies

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Description

Glycidamide is the genotoxic metabolite of Acrylamide. Glycidamide can react with proteins, such as hemoglobin, or with DNA, and induces genotoxic effects[1].

Molecular Weight

87.08

Formula

C3H5NO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N)C1OC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (1435.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 11.4837 mL 57.4185 mL 114.8369 mL
5 mM 2.2967 mL 11.4837 mL 22.9674 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 11.4837 mL 57.4185 mL 114.8369 mL 287.0923 mL
5 mM 2.2967 mL 11.4837 mL 22.9674 mL 57.4185 mL
10 mM 1.1484 mL 5.7418 mL 11.4837 mL 28.7092 mL
15 mM 0.7656 mL 3.8279 mL 7.6558 mL 19.1395 mL
20 mM 0.5742 mL 2.8709 mL 5.7418 mL 14.3546 mL
25 mM 0.4593 mL 2.2967 mL 4.5935 mL 11.4837 mL
30 mM 0.3828 mL 1.9139 mL 3.8279 mL 9.5697 mL
40 mM 0.2871 mL 1.4355 mL 2.8709 mL 7.1773 mL
50 mM 0.2297 mL 1.1484 mL 2.2967 mL 5.7418 mL
60 mM 0.1914 mL 0.9570 mL 1.9139 mL 4.7849 mL
80 mM 0.1435 mL 0.7177 mL 1.4355 mL 3.5887 mL
100 mM 0.1148 mL 0.5742 mL 1.1484 mL 2.8709 mL
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Glycidamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glycidamide5694-00-8Oxiranecarboxamide 2,3-EpoxypropanamideOthersmetabolitegenotoxicInhibitorinhibitorinhibit

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