2. Induced Disease Models Products
  3. Immunology and Inflammatory Disease Models
  4. Gastrointestinal Inflammation and Ulcer Models

Gastrointestinal Inflammation and Ulcer Models

 

Gastrointestinal Inflammation and Ulcer Models (13):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-14397
    Indomethacin 53-86-1 99.94%
    Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research.
    Indomethacin
  • HY-14654
    Aspirin 50-78-2 99.66%
    Aspirin (Acetylsalicylic Acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis.
    Aspirin
  • HY-B1204
    Histamine 51-45-6 99.99%
    Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
    Histamine
  • HY-N0480
    Reserpine 50-55-5 99.83%
    Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
    Reserpine
  • HY-77591
    Cysteamine hydrochloride 156-57-0 ≥98.0%
    Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.
    Cysteamine hydrochloride
  • HY-116282C
    Dextran sulfate sodium salt (MW 35000-45000) 9011-18-1
    Dextran sulfate sodium salt (MW 35000-45000) is a polymer of anhydroglucose with the molecular weight range of 35000-45000. Dextran sulfate sodium salt can be used to induce colitis. Dextran sulfate sodium salt also can inhibit the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells.
    Dextran sulfate sodium salt (MW 35000-45000)
  • HY-A0129
    Histamine phosphate 51-74-1 99.99%
    Histamine (phosphate) is a strong histamine receptor activator and vasodilator neuroagent, capable of activating nitric oxide synthase.
    Histamine phosphate
  • HY-14397A
    Indomethacin sodium hydrate 74252-25-8 99.80%
    Indomethacin (Indometacin) sodium hydrateis a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium hydrateis has anticancer activity and anti-infective activity. Indomethacin sodium hydrateis can be used for cancer, inflammation and viral infection research.
    Indomethacin sodium hydrate
  • HY-B0722
    Histamine dihydrochloride 56-92-8 99.51%
    Histamine dihydrochloride is an endogenous metabolite.
    Histamine dihydrochloride
  • HY-126360
    Oxazolone 15646-46-5 ≥98.0%
    Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins.
    Oxazolone
  • HY-N0480A
    Reserpine hydrochloride 16994-56-2 99.90%
    Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
    Reserpine hydrochloride
  • HY-15034
    Indomethacin sodium 7681-54-1
    Indomethacin (Indometacin) sodium is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium has anticancer activity and anti-infective activity. Indomethacin sodium can be used for cancer, inflammation and viral infection research..
    Indomethacin sodium
  • HY-14654A
    Aspirin lithium 552-98-7
    Aspirin (Acetylsalicylic Acid) lithium is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin lithium induces apoptosis. Aspirin lithium inhibits the activation of NF-κB. Aspirin lithium also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis.
    Aspirin lithium