2. Isotope-Labeled Compounds
  3. Internal Standard for Food

Internal Standard for Food

Food safety issues have become a global topic, and vicious food safety incidents continue to occur internationally, causing huge economic losses. Food safety testing has now become one of the hot topics of concern in various countries. Currently, the most advanced method for food safety testing in the world is isotope dilution mass spectrometry. This method uses stable isotope-labeled compounds (13C, 15N, 2H, etc.) which with the same molecular structure as the analytes as internal standards. Through quantitative mold detection with high-end instruments such as LC-MS and LC-MS/MS, the content of harmful substances in food can be accurately quantified to ensure the safety of food on the market[1].

 

References:

Internal Standard for Food (1042):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0390S1
    L-Glutamine-13C5 184161-19-1 ≥98.0%
    L-Glutamine-13C5 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
    L-Glutamine-<sup>13</sup>C<sub>5</sub>
  • HY-18569S
    3-Indoleacetic acid-d5 76937-78-5 99.84%
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].
    3-Indoleacetic acid-d<sub>5</sub>
  • HY-100807S
    Quinolinic acid-d3 138946-42-6 99.85%
    Quinolinic acid-d3 is the deuterium labeled Quinolinic acid. Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction[1][2].
    Quinolinic acid-d<sub>3</sub>
  • HY-108872S
    Water-18O 14314-42-2 99.99%
    Water-18O is the 18O-labeled Water[1].
    Water-<sup>18</sup>O
  • HY-N0623S
    L-Tryptophan-d5 62595-11-3 99.85%
    L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
    L-Tryptophan-d<sub>5</sub>
  • HY-B1342S2
    Retinol-d4 118063-12-0 ≥98.0%
    Retinol-d4 (Vitamin A1-d4; all-trans-Retinol-d4) is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite.
    Retinol-d4
  • HY-15025S2
    Sildenafil-d3N-1 1126745-87-6 99.47%
    Sildenafil-d3-1 (UK-92480-d3-1) is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.
    Sildenafil-d<sub>3</sub>N<sub>-1
  • HY-B1342S3
    Retinol-13C3
    Retinol-13C3 (Vitamin A1-13C3; all-trans-Retinol-13C3) is a 13C-labeled Vitamin A/Retinol (HY-B1342). Retinol is an endogenous metabolite.
    Retinol-<sup>13</sup>C<sub>3</sub>
  • HY-B0413S
    Fenbendazole-d3 1228182-47-5 99.46%
    Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].
    Fenbendazole-d<sub>3</sub>
  • HY-10219S
    Rapamycin-d3 392711-19-2
    Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1[1]. Rapamycin is an autophagy activator, an immunosuppressant[2].
    Rapamycin-d<sub>3</sub>
  • HY-N0390S
    L-Glutamine-15N 80143-57-3 ≥98.0%
    L-Glutamine-15N is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
    L-Glutamine-<sup>15</sup>N
  • HY-66005S
    Acetaminophen-d4 64315-36-2 99.38%
    Acetaminophen-d4 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].
    Acetaminophen-d<sub>4</sub>
  • HY-N1428S1
    Citric acid-13C6 287389-42-8 ≥99.0%
    Citric acid-13C6 is the 13C-labeled Citric acid. Citric acid is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a natural preservative and food tartness enhancer.
    Citric acid-<sup>13</sup>C<sub>6</sub>
  • HY-N0229S3
    L-Alanine-d4 18806-29-6 99.97%
    L-Alanine-d4 is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
    L-Alanine-d<sub>4</sub>
  • HY-N0771S3
    L-Isoleucine-d10 35045-71-7 ≥98.0%
    L-Isoleucine-d10 is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
    L-Isoleucine-d<sub>10</sub>
  • HY-Y0252S
    L-Proline-13C5 201740-83-2 99.00%
    L-Proline-13C5 is the 13C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
    L-Proline-<sup>13</sup>C<sub>5</sub>
  • HY-B0322S
    Sulfamethoxazole-d4 1020719-86-1 99.56%
    Sulfamethoxazole-d4 is a deuterium labeled Sulfamethoxazole (Ro 4-2130). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic[1].
    Sulfamethoxazole-d<sub>4</sub>
  • HY-N0390S2
    L-Glutamine-d5 14341-78-7 ≥98.0%
    L-Glutamine-d5 is the deuterium labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
    L-Glutamine-d<sub>5</sub>
  • HY-B1337S1
    Choline-d9 chloride 61037-86-3 ≥98.0%
    Choline-d9 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
    Choline-d<sub>9</sub> chloride
  • HY-N1446S1
    Oleic acid-d2 5711-29-5 ≥98.0%
    Oleic acid-d2) is the deuterium labeled Oleic acid. Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid[1]. Oleic acid is a Na+/K+ ATPase activator[2].
    Oleic acid-d<sub>2</sub>