1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Endogenous Metabolite
  3. L-Tyrosine-3,5-13C2

L-Tyrosine-3,5-13C2 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

For research use only. We do not sell to patients.

L-Tyrosine-3,5-<sup>13</sup>C<sub>2</sub> Chemical Structure

L-Tyrosine-3,5-13C2 Chemical Structure

CAS No. : 70479-98-0

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1 mg USD 211 In-stock
5 mg USD 465 In-stock
10 mg USD 745 In-stock
25 mg USD 1490 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

L-Tyrosine-3,5-13C2 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

183.17

Formula

C713C2H11NO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CC1=C[13CH]=C([13CH]=C1)O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 4.81 mg/mL (26.26 mM; ultrasonic and warming and adjust pH to 10 with NaOH and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4594 mL 27.2970 mL 54.5941 mL
5 mM 1.0919 mL 5.4594 mL 10.9188 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.4594 mL 27.2970 mL 54.5941 mL 136.4852 mL
5 mM 1.0919 mL 5.4594 mL 10.9188 mL 27.2970 mL
10 mM 0.5459 mL 2.7297 mL 5.4594 mL 13.6485 mL
15 mM 0.3640 mL 1.8198 mL 3.6396 mL 9.0990 mL
20 mM 0.2730 mL 1.3649 mL 2.7297 mL 6.8243 mL
25 mM 0.2184 mL 1.0919 mL 2.1838 mL 5.4594 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-Tyrosine-3,5-13C2
Cat. No.:
HY-N0473S6
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