1. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  2. LXR
  3. LXR agonist 1

LXR (Liver X receptor) agonist 1 is potent LXR agonist with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively. LXR agonist 1 has the potential for the research of atherosclerosis.

For research use only. We do not sell to patients.

LXR agonist 1 Chemical Structure

LXR agonist 1 Chemical Structure

CAS No. : 1779524-90-1

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Description

LXR (Liver X receptor) agonist 1 is potent LXR agonist with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively. LXR agonist 1 has the potential for the research of atherosclerosis[1].

IC50 & Target

AC50: 1.5 nM (LXR-α); 12 nM (LXR-β)[1]

In Vitro

LXR agonist 1 (compound 3) shows binding affinities with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

529.57

Formula

C27H26F3N3O3S

CAS No.
SMILES

CCC1=C(C2=CC=CC(OC3=CC(S(N(C)CCN)(=O)=O)=CC=C3)=C2)C4=CC=CC(C(F)(F)F)=C4N=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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LXR agonist 1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
LXR agonist 1
Cat. No.:
HY-144549
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