2. Academic Validation
  3. Microbial transformation of fraxinellone by Aspergillus niger

Microbial transformation of fraxinellone by Aspergillus niger

  • J Asian Nat Prod Res. 2005 Dec;7(6):843-5. doi: 10.1080/10286020310001653318.
R-L Yang 1,  T-L Jia,  R-Q Zhang
Affiliations

Affiliation

  • 1 Institute of Marine Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China.
PMID: 16308202 DOI: 10.1080/10286020310001653318
Abstract

Microbial transformation of fraxinellone (1) by Aspergillus niger (AS 3.421) has been carried out. Two converted products, dasycarpol (2) and a new compound fraxinigerllone (3) were obtained. Their structures have been identified on the basis of spectroscopic methods. Dasycarpol shows moderate inhibitory activity on lung Cancer cell line A549.

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