1. GPCR/G Protein Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE) Adenylate Cyclase
  3. MDL12330A

MDL12330A  (Synonyms: RMI12330A)

Cat. No.: HY-103192 Purity: ≥99.0%
COA Handling Instructions

MDL12330A (RMI12330A) is an adenyl cyclase inhibitor. MDL12330A inhibits the vasopressin action on the short-circuit current (SCC). MDL12330A is also an inhibitor of cAMP phosphodiesterase.

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MDL12330A Chemical Structure

MDL12330A Chemical Structure

CAS No. : 40297-09-4

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Description

MDL12330A (RMI12330A) is an adenyl cyclase inhibitor. MDL12330A inhibits the vasopressin action on the short-circuit current (SCC). MDL12330A is also an inhibitor of cAMP phosphodiesterase[1].

Molecular Weight

377.01

Formula

C23H37ClN2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[H]Cl.C1(/N[C@@H]2[C@H](C3=CC=CC=C3)CCC2)=N/CCCCCCCCCCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (66.31 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6524 mL 13.2622 mL 26.5245 mL
5 mM 0.5305 mL 2.6524 mL 5.3049 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6524 mL 13.2622 mL 26.5245 mL 66.3112 mL
5 mM 0.5305 mL 2.6524 mL 5.3049 mL 13.2622 mL
10 mM 0.2652 mL 1.3262 mL 2.6524 mL 6.6311 mL
15 mM 0.1768 mL 0.8841 mL 1.7683 mL 4.4207 mL
20 mM 0.1326 mL 0.6631 mL 1.3262 mL 3.3156 mL
25 mM 0.1061 mL 0.5305 mL 1.0610 mL 2.6524 mL
30 mM 0.0884 mL 0.4421 mL 0.8841 mL 2.2104 mL
40 mM 0.0663 mL 0.3316 mL 0.6631 mL 1.6578 mL
50 mM 0.0530 mL 0.2652 mL 0.5305 mL 1.3262 mL
60 mM 0.0442 mL 0.2210 mL 0.4421 mL 1.1052 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MDL12330A
Cat. No.:
HY-103192
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