1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. nAChR iGluR
  3. Meclofenoxate hydrochloride

Meclofenoxate hydrochloride  (Synonyms: Centrophenoxine hydrochloride)

Cat. No.: HY-17555 Purity: 98.80%
COA Handling Instructions

Meclofenoxate hydrochloride is an ester synthesized from DMAE and pCPA, which has the activity of stimulating memory and improving cognition.

For research use only. We do not sell to patients.

Meclofenoxate hydrochloride Chemical Structure

Meclofenoxate hydrochloride Chemical Structure

CAS No. : 3685-84-5

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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 86 In-stock
Solution
10 mM * 1 mL in DMSO USD 86 In-stock
Solid
100 mg USD 78 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Meclofenoxate hydrochloride:

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Meclofenoxate hydrochloride is an ester synthesized from DMAE and pCPA, which has the activity of stimulating memory and improving cognition.

Clinical Trial
Molecular Weight

294.17

Formula

C12H17Cl2NO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(OCC(OCCN(C)C)=O)C=C1.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (169.97 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 33.33 mg/mL (113.30 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3994 mL 16.9970 mL 33.9939 mL
5 mM 0.6799 mL 3.3994 mL 6.7988 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (339.94 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.3994 mL 16.9970 mL 33.9939 mL 84.9849 mL
5 mM 0.6799 mL 3.3994 mL 6.7988 mL 16.9970 mL
10 mM 0.3399 mL 1.6997 mL 3.3994 mL 8.4985 mL
15 mM 0.2266 mL 1.1331 mL 2.2663 mL 5.6657 mL
20 mM 0.1700 mL 0.8498 mL 1.6997 mL 4.2492 mL
25 mM 0.1360 mL 0.6799 mL 1.3598 mL 3.3994 mL
30 mM 0.1133 mL 0.5666 mL 1.1331 mL 2.8328 mL
40 mM 0.0850 mL 0.4249 mL 0.8498 mL 2.1246 mL
50 mM 0.0680 mL 0.3399 mL 0.6799 mL 1.6997 mL
60 mM 0.0567 mL 0.2833 mL 0.5666 mL 1.4164 mL
80 mM 0.0425 mL 0.2125 mL 0.4249 mL 1.0623 mL
100 mM 0.0340 mL 0.1700 mL 0.3399 mL 0.8498 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Meclofenoxate hydrochloride Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Meclofenoxate hydrochloride
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