Methyl palmitoleate (Synonyms: (Z)-Methyl hexadec-9-enoate; Methyl cis-9-Hexadecenoate)

Name: Methyl palmitoleate
Brand: MedChemExpress
SKU: HY-W011688
Rating: 4.5 (1 reviews)

Cat. No.: HY-W011688 Purity: 98.08%: FAQs
Data Sheet SDS COA Handling Instructions

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Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties.

For research use only. We do not sell to patients.

Methyl palmitoleate Chemical Structure

CAS No. : 1120-25-8

Size	Price	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 33	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 33	In-stock	Estimated Time of Arrival: December 31
Liquid
100 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
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5 g		Get quote

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Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE Methyl palmitoleate

•Gut Microbes. 2023 Dec;15(2):2265578. [Abstract]

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Description

Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties^[1].

Molecular Weight

268.43

Formula

C₁₇H₃₂O₂

CAS No.

1120-25-8

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(OC)CCCCCCC/C=C\CCCCCC

Structure Classification

Others

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (372.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7254 mL	18.6268 mL	37.2537 mL
5 mM	0.7451 mL	3.7254 mL	7.4507 mL
10 mM	0.3725 mL	1.8627 mL	3.7254 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (9.31 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (9.31 mM); Suspended solution; Need ultrasonic

This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (9.31 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 98.08%

Select Batch:

Data Sheet (266 KB) SDS (0 KB)

COA (238 KB) HNMR (254 KB) MS (69 KB) GC (190 KB)

Handling Instructions (2659 KB)

References

[1]. Eleftheria Diakogiannaki, et al. Mechanisms Involved in the Cytotoxic and Cytoprotective Actions of Saturated Versus Monounsaturated Long-Chain Fatty Acids in Pancreatic Beta-Cells. J Endocrinol. 2007 Aug;194(2):283-91. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7254 mL	18.6268 mL	37.2537 mL	93.1342 mL
	5 mM	0.7451 mL	3.7254 mL	7.4507 mL	18.6268 mL
	10 mM	0.3725 mL	1.8627 mL	3.7254 mL	9.3134 mL
	15 mM	0.2484 mL	1.2418 mL	2.4836 mL	6.2089 mL
	20 mM	0.1863 mL	0.9313 mL	1.8627 mL	4.6567 mL
	25 mM	0.1490 mL	0.7451 mL	1.4901 mL	3.7254 mL
	30 mM	0.1242 mL	0.6209 mL	1.2418 mL	3.1045 mL
	40 mM	0.0931 mL	0.4657 mL	0.9313 mL	2.3284 mL
	50 mM	0.0745 mL	0.3725 mL	0.7451 mL	1.8627 mL
	60 mM	0.0621 mL	0.3104 mL	0.6209 mL	1.5522 mL
	80 mM	0.0466 mL	0.2328 mL	0.4657 mL	1.1642 mL
	100 mM	0.0373 mL	0.1863 mL	0.3725 mL	0.9313 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methyl palmitoleate1120-25-8(Z)-Methyl hexadec-9-enoate Methyl cis-9-HexadecenoateOthersPalmitoleatecytoprotectivefattyacidmethylesterInhibitorinhibitorinhibit

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Methyl palmitoleate (Synonyms: (Z)-Methyl hexadec-9-enoate; Methyl cis-9-Hexadecenoate)

Customer Review

Methyl palmitoleate Related Antibodies

1 Publications Citing Use of MCE Methyl palmitoleate

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

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