2. PI3K/Akt/mTOR Anti-infection
  3. PI4K HCV
  4. MI 14

MI 14 is a selective PI4KIIIβ inhibitor with IC50s of 54 nM, >100 μM, >100 μM for PI4KIIIβ, PI4KIIIα, PI4KIIα, respectively. MI 14 has antiviral activity against HCV 1b, CVB3, HRVM, HVC 2a.

For research use only. We do not sell to patients.

MI 14 Chemical Structure

MI 14 Chemical Structure

CAS No. : 1715934-43-2

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Based on 1 publication(s) in Google Scholar

MI 14 Related Antibodies

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Description

MI 14 is a selective PI4KIIIβ inhibitor with IC50s of 54 nM, >100 μM, >100 μM for PI4KIIIβ, PI4KIIIα, PI4KIIα, respectively. MI 14 has antiviral activity against HCV 1b, CVB3, HRVM, HVC 2a[1].

IC50 & Target[1]

PI4KIIIβ

54 nM (IC50)

PI4KIIIα

>100 μM (IC50)

PI4KIIα

>100 μM (IC50)

In Vitro

MI 14 (compound 36t) has antiviral activity against HCV 1b (EC50=0.087 µM), CVB3 (EC50=0.145 µM), HRVM (EC50=1.03 µM), HVC 2a (EC50=10.6 µM) in HeLa cells[1].
MI 14 has no inhibition on phosphatidylinositol 3-kinases (PI3Ka, PI3Kb, PI3Kd and PI3Kg) with IC50s up to 10 µM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MI 14 Related Antibodies
Molecular Weight

450.94

Formula

C19H23ClN6O3S
CAS No.
SMILES

O=C(C)NCCNC1=CC(Cl)=NN2C1=NC(C)=C2C3=CC(S(=O)(N(C)C)=O)=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MI 14 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MI 141715934-43-2MI14MI-14PI4KHCVPhosphatidylinositol 4 kinasesPI4 kinasesHepatitis C virusAntiviralHCV 1bCVB3HRVMHVC 2aInhibitorinhibitorinhibit

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