MuRF1-IN-2

Cat. No.: HY-W184800 Purity: 95.23%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor. MuRF1-IN-2 can be used for research of muscle wasting conditions, of skeletal or cardial muscle atrophy.

For research use only. We do not sell to patients.

MuRF1-IN-2 Chemical Structure

CAS No. : 937891-74-2

Size	Price	Stock	Quantity
10 mg	USD 40	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 78	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 125	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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References
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Description

MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor. MuRF1-IN-2 can be used for research of muscle wasting conditions, of skeletal or cardial muscle atrophy^[1].

IC₅₀ & Target

MuRF1^[1]

Molecular Weight

438.43

Formula

C₂₃H₂₂N₂O₇

CAS No.

937891-74-2

Appearance

Solid

Color

Off-white to light brown

SMILES

O=C(OC(C)C(NC(NC)=O)=O)C1=CC=C(COC2=CC(O3)=C(C=C2)C(C)=CC3=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (114.04 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2809 mL	11.4043 mL	22.8087 mL
5 mM	0.4562 mL	2.2809 mL	4.5617 mL
10 mM	0.2281 mL	1.1404 mL	2.2809 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.23%

Select Batch:

Data Sheet (267 KB) SDS (393 KB)

COA (244 KB) HNMR (282 KB) LCMS (268 KB)

Handling Instructions (2659 KB)

References

[1]. Adams, Volker, et al. Preparation of chromen-2-one compounds suitable for the treatment and prophylaxis of muscle wasting and other conditions. Patent. WO2021032643.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2809 mL	11.4043 mL	22.8087 mL	57.0216 mL
	5 mM	0.4562 mL	2.2809 mL	4.5617 mL	11.4043 mL
	10 mM	0.2281 mL	1.1404 mL	2.2809 mL	5.7022 mL
	15 mM	0.1521 mL	0.7603 mL	1.5206 mL	3.8014 mL
	20 mM	0.1140 mL	0.5702 mL	1.1404 mL	2.8511 mL
	25 mM	0.0912 mL	0.4562 mL	0.9123 mL	2.2809 mL
	30 mM	0.0760 mL	0.3801 mL	0.7603 mL	1.9007 mL
	40 mM	0.0570 mL	0.2851 mL	0.5702 mL	1.4255 mL
	50 mM	0.0456 mL	0.2281 mL	0.4562 mL	1.1404 mL
	60 mM	0.0380 mL	0.1901 mL	0.3801 mL	0.9504 mL
	80 mM	0.0285 mL	0.1426 mL	0.2851 mL	0.7128 mL
	100 mM	0.0228 mL	0.1140 mL	0.2281 mL	0.5702 mL

MuRF1-IN-2 Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MuRF1-IN-2937891-74-2Othersmuscle wasting conditionsskeletal atrophycardial muscle atrophyInhibitorinhibitorinhibit

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