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OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity.

For research use only. We do not sell to patients.

OU749 Chemical Structure

OU749 Chemical Structure

CAS No. : 519170-13-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 80 In-stock
Solution
10 mM * 1 mL in DMSO USD 80 In-stock
Solid
1 mg USD 35 In-stock
5 mg USD 100 In-stock
10 mg USD 160 In-stock
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Based on 1 publication(s) in Google Scholar

OU749 Related Antibodies

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Description

OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity[1].

IC50 & Target

Ki: 17.6 µM (GGT)[1]
In Vitro

OU749 (compound 3) (3 days) shows cytotoxicity with an LD50 value of 128 µM for 786-O cells[1].
OU749 (0-1000 µM) inhibits GGT (γ-glutamyl transpeptidase) activity in a dose-dependent manner in 786-O and HK-2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

OU749 Related Antibodies
Molecular Weight

361.44

Formula

C16H15N3O3S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=CC=C1)(NC2=NN=C(CC3=CC=C(OC)C=C3)S2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (345.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7667 mL 13.8336 mL 27.6671 mL
5 mM 0.5533 mL 2.7667 mL 5.5334 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7667 mL 13.8336 mL 27.6671 mL 69.1678 mL
5 mM 0.5533 mL 2.7667 mL 5.5334 mL 13.8336 mL
10 mM 0.2767 mL 1.3834 mL 2.7667 mL 6.9168 mL
15 mM 0.1844 mL 0.9222 mL 1.8445 mL 4.6112 mL
20 mM 0.1383 mL 0.6917 mL 1.3834 mL 3.4584 mL
25 mM 0.1107 mL 0.5533 mL 1.1067 mL 2.7667 mL
30 mM 0.0922 mL 0.4611 mL 0.9222 mL 2.3056 mL
40 mM 0.0692 mL 0.3458 mL 0.6917 mL 1.7292 mL
50 mM 0.0553 mL 0.2767 mL 0.5533 mL 1.3834 mL
60 mM 0.0461 mL 0.2306 mL 0.4611 mL 1.1528 mL
80 mM 0.0346 mL 0.1729 mL 0.3458 mL 0.8646 mL
100 mM 0.0277 mL 0.1383 mL 0.2767 mL 0.6917 mL
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OU749 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OU749519170-13-9OU 749OU-749Others786-OHK-2 cellscytotoxicityInhibitorinhibitorinhibit

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