1. Peptides
  2. Oxytocin parallel dimer

Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin.

For research use only. We do not sell to patients.

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Oxytocin parallel dimer Chemical Structure

Oxytocin parallel dimer Chemical Structure

CAS No. : 19645-28-4

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5 mg USD 1080 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin[1][2].

In Vitro

The parallel and antiparallel homo/hetero bis-cystine dimers of oxytocin and deamino-oxytocin show biological activities ranged from 0.2% to 6% that of oxytocin[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Oxytocin dimer (iv; single dose) shows acute toxicity (LD50=43 mg/kg) is less than that of oxytocin (LD50=25 mg/kg) in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2014.37

Formula

C86H132N24O24S4

CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

Sequence 1:CYIQNCPLG-NH2;Sequence 2:CYIQNCPLG-NH2 (Disulfide bridge:Chain1 Cys1 to Chain2 Cys1;Chain1 Cys6 to Chain2 Cys6)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (12.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4964 mL 2.4822 mL 4.9643 mL
5 mM 0.0993 mL 0.4964 mL 0.9929 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4964 mL 2.4822 mL 4.9643 mL 12.4108 mL
5 mM 0.0993 mL 0.4964 mL 0.9929 mL 2.4822 mL
10 mM 0.0496 mL 0.2482 mL 0.4964 mL 1.2411 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Oxytocin parallel dimer
Cat. No.:
HY-P3215
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