2. GPCR/G Protein Neuronal Signaling
  3. Neuropeptide Y Receptor
  4. Pancreatic polypeptide

Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion.

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Pancreatic polypeptide Chemical Structure

Pancreatic polypeptide Chemical Structure

CAS No. : 59763-91-6

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Pancreatic polypeptide Related Antibodies

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Description

Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion[1].

In Vitro

Pancreatic polypeptid (PP) (0.1 μM, 48 h) causes a significant reduction in growth inhibitory hormone secretion in mHippo E18 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Pancreatic polypeptide Related Antibodies
In Vivo

Pancreatic polypeptid (PP)(1 μM, Hippocampal injection, 0.2 μL/min followed by 3 min) stimulates the expression of the neuronal activation marker c-Fos in growth inhibitor-containing cells in the male B6C3F1/J mice brain, indicating that it activates growth inhibitor-containing cells in the mouse hippocampus[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

4182.70

Formula

C185H286N52O55S2
CAS No.
Sequence

Ala-Pro-Leu-Glu-Pro-Val-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Asp-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
Sequence Shortening

APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY-NH2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pancreatic polypeptide Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pancreatic polypeptide59763-91-6Neuropeptide Y ReceptorNPY receptorendocrine PPpancreatic secretoryhepatic glycogenInhibitorinhibitorinhibit

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