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PDCD4-IN-1(compound 20031600) is a PDCD4 inhibitor with a Kd value of 350 nM, which can promote the expression of BDNF in hippocampal neuron cell HT-22.

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PDCD4-IN-1 Chemical Structure

PDCD4-IN-1 Chemical Structure

CAS No. : 494763-64-3

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Based on 1 publication(s) in Google Scholar

PDCD4-IN-1 Related Antibodies

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Description

PDCD4-IN-1(compound 20031600) is a PDCD4 inhibitor with a Kd value of 350 nM, which can promote the expression of BDNF in hippocampal neuron cell HT-22[1].

Molecular Weight

326.58

Formula

C12H9BrClN3O
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(C1=CC(Br)=CN=C1)NNC2=CC=CC(Cl)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (765.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0620 mL 15.3102 mL 30.6204 mL
5 mM 0.6124 mL 3.0620 mL 6.1241 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0620 mL 15.3102 mL 30.6204 mL 76.5509 mL
5 mM 0.6124 mL 3.0620 mL 6.1241 mL 15.3102 mL
10 mM 0.3062 mL 1.5310 mL 3.0620 mL 7.6551 mL
15 mM 0.2041 mL 1.0207 mL 2.0414 mL 5.1034 mL
20 mM 0.1531 mL 0.7655 mL 1.5310 mL 3.8275 mL
25 mM 0.1225 mL 0.6124 mL 1.2248 mL 3.0620 mL
30 mM 0.1021 mL 0.5103 mL 1.0207 mL 2.5517 mL
40 mM 0.0766 mL 0.3828 mL 0.7655 mL 1.9138 mL
50 mM 0.0612 mL 0.3062 mL 0.6124 mL 1.5310 mL
60 mM 0.0510 mL 0.2552 mL 0.5103 mL 1.2758 mL
80 mM 0.0383 mL 0.1914 mL 0.3828 mL 0.9569 mL
100 mM 0.0306 mL 0.1531 mL 0.3062 mL 0.7655 mL
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PDCD4-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PDCD4-IN-1494763-64-3OthersInhibitorinhibitorinhibit

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