2. Stem Cell/Wnt TGF-beta/Smad Apoptosis
  3. TGF-beta/Smad Apoptosis
  4. Pentabromophenol

Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-β (TGF-β) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-β signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs).

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Pentabromophenol Chemical Structure

Pentabromophenol Chemical Structure

CAS No. : 608-71-9

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Pentabromophenol Related Antibodies

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Description

Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-β (TGF-β) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-β signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs)[1][2].

Molecular Weight

488.59

Formula

C6HBr5O
CAS No.
SMILES

C1(=C(C(=C(C(=C1Br)Br)O)Br)Br)Br
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Pentabromophenol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pentabromophenol608-71-9PBPTGF-beta/SmadApoptosisTransforming growth factor betaA549NMuMGapoptosisperipheral blood mononuclear cells (PBMCs)Inhibitorinhibitorinhibit

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