Propantheline-d₃ bromide

Name: Propantheline-d 3 bromide
Brand: MedChemExpress
SKU: HY-B1188S
Rating: 4.5 (1 reviews)

Cat. No.: HY-B1188S Purity: 99.00%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Propantheline-d₃ (bromide) is the deuterium labeled Propantheline bromide. Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.

For research use only. We do not sell to patients.

Propantheline-d<sub>3</sub> bromide Chemical Structure

Propantheline-d₃ bromide Chemical Structure

CAS No. : 64717-35-7

Size	Price	Stock	Quantity
1 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 450	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 740	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Propantheline-d₃ bromide:

Propantheline bromide In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

451.41

Formula

C₂₃H₂₇D₃BrNO₃

CAS No.

64717-35-7

Appearance

Solid

Color

Off-white to light yellow

SMILES

CC(C)[N+](C(C)C)(C([2H])([2H])[2H])CCOC(C1C2=CC=CC=C2OC3=CC=CC=C31)=O.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (221.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2153 mL	11.0764 mL	22.1528 mL
5 mM	0.4431 mL	2.2153 mL	4.4306 mL
10 mM	0.2215 mL	1.1076 mL	2.2153 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.00%

Select Batch:

Data Sheet (275 KB) SDS (251 KB)

COA (256 KB) HNMR (118 KB) RP-HPLC (164 KB) LCMS (111 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2153 mL	11.0764 mL	22.1528 mL	55.3820 mL
	5 mM	0.4431 mL	2.2153 mL	4.4306 mL	11.0764 mL
	10 mM	0.2215 mL	1.1076 mL	2.2153 mL	5.5382 mL
	15 mM	0.1477 mL	0.7384 mL	1.4769 mL	3.6921 mL
	20 mM	0.1108 mL	0.5538 mL	1.1076 mL	2.7691 mL
	25 mM	0.0886 mL	0.4431 mL	0.8861 mL	2.2153 mL
	30 mM	0.0738 mL	0.3692 mL	0.7384 mL	1.8461 mL
	40 mM	0.0554 mL	0.2769 mL	0.5538 mL	1.3846 mL
	50 mM	0.0443 mL	0.2215 mL	0.4431 mL	1.1076 mL
	60 mM	0.0369 mL	0.1846 mL	0.3692 mL	0.9230 mL
	80 mM	0.0277 mL	0.1385 mL	0.2769 mL	0.6923 mL
	100 mM	0.0222 mL	0.1108 mL	0.2215 mL	0.5538 mL