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  5. PSG1 Protein, Human (HEK 293, hFc)

PSG1 Protein, Human (HEK 293, hFc)

Cat. No.: HY-P72486A
COA Handling Instructions

Pregnancy-specific beta-1-glycoprotein 1 (PSG1), originating from the syncytiotrophoblast, attains concentrations of 100 to 290 mg/l in the serum of pregnant women at term. As a vital component of the human placenta, PSG1's molecular characteristics, within the immunoglobulin (Ig) superfamily, contribute to its essential role in supporting pregnancy. With a restricted expression primarily localized to the placenta (RPKM 224.3), PSG1 underscores its significance as a major contributor to the hormonal milieu essential for fetal survival and development during pregnancy. PSG1 Protein, Human (HEK 293, hFc) is the recombinant human-derived PSG1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of PSG1 Protein, Human (HEK 293, hFc) is 385 a.a., with molecular weight of ~95 KDa.

For research use only. We do not sell to patients.

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Description

Pregnancy-specific beta-1-glycoprotein 1 (PSG1), originating from the syncytiotrophoblast, attains concentrations of 100 to 290 mg/l in the serum of pregnant women at term. As a vital component of the human placenta, PSG1's molecular characteristics, within the immunoglobulin (Ig) superfamily, contribute to its essential role in supporting pregnancy. With a restricted expression primarily localized to the placenta (RPKM 224.3), PSG1 underscores its significance as a major contributor to the hormonal milieu essential for fetal survival and development during pregnancy. PSG1 Protein, Human (HEK 293, hFc) is the recombinant human-derived PSG1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of PSG1 Protein, Human (HEK 293, hFc) is 385 a.a., with molecular weight of ~95 KDa.

Background

Pregnancy-specific beta-1-glycoprotein 1 (PSG1) is a prominent constituent of the human placenta, a vital endocrine organ crucial for sustaining fetal well-being. Originating from the syncytiotrophoblast, PSG1 attains concentrations of 100 to 290 mg/l in the serum of pregnant women at term. Classified within the immunoglobulin (Ig) superfamily, PSG1's molecular characteristics contribute to its essential role in supporting pregnancy. With a restricted expression primarily localized to the placenta (RPKM 224.3), PSG1 underscores its significance as a major contributor to the hormonal milieu essential for fetal survival and development during pregnancy.

Biological Activity

Data is not available.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

NP_001171754.1 (Q35-P419)

Gene ID

5669

Molecular Construction
N-term
PSG1 (Q35-P419)
Accession # NP_001171754.1
hFc
C-term
Synonyms
PSG1; Pregnancy-specific beta-1-glycoprotein 1
Molecular Weight

Approximately 95 kDa.

Purity
  • Greater than 90% as determined by reducing SDS-PAGE.
Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
PSG1 Protein, Human (HEK 293, hFc)
Cat. No.:
HY-P72486A
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