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SLC25A37 Protein, Human (Sf9, His, MBP, FLAG)

Cat. No.: HY-P702044
Handling Instructions

The SLC25A37 protein is a mitochondrial iron transporter that specifically promotes iron uptake by developing erythrocytes, which is critical for heme biosynthesis. By mediating iron transport into red blood cell mitochondria, SLC25A37 supports heme synthesis, which is critical for various biological processes including hemoglobin formation. SLC25A37 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC25A37 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC25A37 Protein, Human (Sf9, His, MBP, FLAG) is 337 a.a., .

For research use only. We do not sell to patients.

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Description

The SLC25A37 protein is a mitochondrial iron transporter that specifically promotes iron uptake by developing erythrocytes, which is critical for heme biosynthesis. By mediating iron transport into red blood cell mitochondria, SLC25A37 supports heme synthesis, which is critical for various biological processes including hemoglobin formation. SLC25A37 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC25A37 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC25A37 Protein, Human (Sf9, His, MBP, FLAG) is 337 a.a., .

Background

SLC25A37 protein is a mitochondrial iron transporter with a specific function in facilitating iron uptake in developing erythroid cells. This transporter plays a crucial and dedicated role in the process of heme biosynthesis. By mediating the transport of iron into the mitochondria of erythroid cells, SLC25A37 contributes to the synthesis of heme, an essential component involved in various biological processes, particularly in the formation of hemoglobin. The specialized function of SLC25A37 underscores its significance in supporting the maturation of erythroid cells and ensuring the proper production of heme, which is vital for the formation and function of red blood cells.

Species

Human

Source

Sf9 insect cells

Tag

N-MBP;C-Flag;N-8*His

Accession

Q9NYZ2 (E2-Y338)

Gene ID

51312

Molecular Construction
N-term
8*His-MBP
SLC25A37 (E2-Y338)
Accession # Q9NYZ2
Flag
C-term
Synonyms
SLC25A37; Mitoferrin-1; Mitochondrial iron transporter 1; Mitochondrial solute carrier protein; Solute carrier family 25 member 37
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

SLC25A37 Protein, Human (Sf9, His, MBP, FLAG) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SLC25A37 Protein, Human (Sf9, His, MBP, FLAG)
Cat. No.:
HY-P702044
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