SLC25A46 Protein, Human (Sf9, His, MBP, FLAG)

SLC25A46 is a mitochondrial outer membrane transmembrane protein that critically regulates mitochondrial organization by affecting the MICOS complex and participating in mitochondrial cristae biogenesis. Its association with EMC suggests involvement in mitochondrial lipid homeostasis and fission. SLC25A46 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC25A46 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC25A46 Protein, Human (Sf9, His, MBP, FLAG) is 417 a.a., .

SLC25A46, a transmembrane protein located in the mitochondrial outer membrane, plays a crucial role in governing mitochondrial organization. It is implicated in the regulation of the MICOS complex, essential for the biogenesis and dynamics of mitochondrial cristae—invaginations of the inner mitochondrial membrane. Additionally, SLC25A46 is associated with the EMC, indicating its potential involvement in modulating mitochondrial lipid homeostasis and influencing mitochondrial fission. The intricate interplay of SLC25A46 with these molecular complexes underscores its significance in orchestrating key aspects of mitochondrial structure and function.

Human

Sf9 insect cells

N-MBP;C-Flag;N-8*His

Q96AG3 (H2-I418)

91137

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.