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  3. SDZ 220-581 Ammonium salt

SDZ 220-581 Ammonium salt is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7.

For research use only. We do not sell to patients.

SDZ 220-581 Ammonium salt Chemical Structure

SDZ 220-581 Ammonium salt Chemical Structure

CAS No. : 179411-94-0

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5 mg USD 116 In-stock
10 mg USD 180 In-stock
50 mg USD 768 In-stock
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Description

SDZ 220-581 Ammonium salt is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7[1].

IC50 & Target

pKi: 7.7 (NMDA receptor)[1]

In Vivo

SDZ 220-581 (3.2-32 mg/kg; oral administration; for 24 hours; male OF-l mice) treatment dose-dependently protects mice against maximal electroshock seizures (MES). The time-course of protection by SDZ 220-581 is characterized by a rapid onset and long duration of action[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male OF-l mice (18-26 g)[1]
Dosage: 3.2 mg/kg, 10 mg/kg, 32 mg/kg
Administration: Oral administration; for 24 hours
Result: Dose-dependently protected mice against maximal electroshock seizures (MES) upon oral administration.
Molecular Weight

386.77

Formula

C16H20ClN2O5P

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

ClC1=CC=CC=C1C2=CC(C[C@H](N)C(O)=O)=CC(CP(O)(O)=O)=C2.N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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SDZ 220-581 Ammonium salt Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SDZ 220-581 Ammonium salt
Cat. No.:
HY-13059A
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