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Results for "

β-Amyloid (1-8)

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

4

Peptides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1047
    β-Sheet Breaker Peptide iAβ5

    [Pro18, Asp21] β-Amyloid (17-21)

    		 Amyloid-β Neurological Disease
    β-Sheet Breaker Peptide iAβ5 is a potent degrader of cerebral amyloid-beta (Abeta). Abeta deposition is associatied with the Alzheimer disease (AD), due to its related toxicity linked to its beta-sheet conformation and/or aggregation. β-Sheet Breaker Peptide iAβ5 reproducibly induces in vivo disassembly of fibrillar amyloid deposits. Thus, β-Sheet Breaker Peptide iAβ5 prevents and/or reverses neuronal shrinkage caused by Abeta, and reduces the extent of interleukin-1beta positive microglia-like cells that surround the Abeta deposits. β-Sheet Breaker Peptide iAβ5 reduces the size and/or number of cerebral amyloid plaques in AD. β-Sheet Breaker Peptide iAβ5 labeled by hydrophobic benzyl alcohol (HBA) tag, can be used for quantitative assay by showing vivid blue color under acidic conditions .
    β-Sheet Breaker Peptide iAβ5
  • HY-P5946
    β-Amyloid (1-8)

    		Amyloid-β Others
    β-Amyloid (1-8) is aAβ Fragment.
    <em>β-Amyloid</em> (<em>1-8</em>)
  • HY-P5945
    β-Amyloid (1-8, A2V)

    		Amyloid-β Neurological Disease
    β-Amyloid (1-8, A2V) is amutantion of β-Amyloid (1-8) (HY-P5946).
    <em>β-Amyloid</em> (<em>1-8</em>, A2V)
  • HY-P1879
    β-Amyloid (18-28)

    		Amyloid-β Neurological Disease
    β-Amyloid (18-28) is a peptide fragment of β-Amyloid.
    <em>β-Amyloid</em> (<em>18</em>-28)
  • HY-151554
    SQ-3

    		Amyloid-β Others
    SQ-3 is a quinoline analogue, displays moderate selectivity for α-syn aggregates (Ki=39.3 nM) over β-amyloid (Aβ) aggregates (Ki=230 nM). [ 18F]SQ3 has basic properties as a lead compound for the development of a useful α-syn imaging probe .
    SQ-3
  • HY-157441
    AChE/Aβ-IN-4

    		Cholinesterase (ChE) Amyloid-β Neurological Disease
    AChE/Aβ-IN-4 is a dual inhibitor of acetylcholinesterase (AChE) and β-amyloid (Aβ) aggregation, with the IC50 values of 1.72 ± 0.18 μM and 1.42 ± 0.3 μM, respectively. AChE/Aβ-IN-4 plays an impotant role in neurological disorders, such as Alzheimer’s disease .
    AChE/Aβ-IN-4

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