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Results for "

(BRG1)/SMARCA4

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-144835
    FHD-286
    1 Publications Verification

    		 Oxidative Phosphorylation Epigenetic Reader Domain Cancer
    FHD-286 is a selective, oral inhibitor of SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor. FHD-286 has the potential for the research of BAF (BRG1/BRM-associated factor)-related disorders such as acute myeloid leukemia [1].
    FHD-286
  • HY-144896
    FHT-1015
    1 Publications Verification

    		 Epigenetic Reader Domain Cancer
    FHT-1205 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 67) [1].
    FHT-1015
  • HY-144897
    FHT-1204

    		Epigenetic Reader Domain Cancer
    FHT-1204 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 70) [1].
    FHT-1204
  • HY-119374
    BRM/BRG1 ATP Inhibitor-1
    Maximum Cited Publications
    16 Publications Verification

    		 Epigenetic Reader Domain Cancer
    BRM/BRG1 ATP Inhibitor-1 (compound 14) is an orally active allosteric dual brahma homolog (BRM)/SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2 (SMARCA2) and brahma related gene 1 (BRG1)/SMARCA4 ATPase activity inhibitor, both IC50s are below 0.005 µM. BRM/BRG1 ATP Inhibitor-1 has anticancer activity [1].
    BRM/BRG1 ATP Inhibitor-1

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