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Results for "

20E

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

3

Natural
Products

2

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115365
    (3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol

    		Others Others
    (3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol is a steroid-based allylic alcohol.
    (3β,<em>20E</em>)-24-Norchola-5,<em>20</em>(22)-diene-3,23-diol
  • HY-N0179
    Ecdysone

    α-Ecdysone

    		 Endogenous Metabolite Apoptosis Metabolic Disease
    Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979) .
    Ecdysone
  • HY-N6979
    Crustecdysone
    4 Publications Verification

    20-Hydroxyecdysone

    		 Caspase Autophagy Endogenous Metabolite Cardiovascular Disease
    Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
    Crustecdysone
  • HY-146977
    LDHA/PDKs-IN-1

    		PDK-1 Cancer
    LDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 0.8 and 0.15 μM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with an EC50 of 13.2 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research of cancer diseases .
    LDHA/PDKs-IN-1
  • HY-N1611
    19,20-(E)-Vallesamine

    (E)-Vallesamine

    		 Others Others
    19,20-(E)-Vallesamine is an indole alkaloid compound isolated from the stems of Ervatamia yunnanensis .
    19,<em>20-(E</em>)-Vallesamine
  • HY-N0959
    (16R)-E-Isositsirikine

    16(R)-19,20-E-Isositsirikine
    (16R)-E-Isositsirikine is an indole alkaloid compound from Catharanthus roseus Tissue Cultures IV1 .
    (16R)-E-Isositsirikine
  • HY-110287
    Apcin
    3 Publications Verification

    		 APC Cancer
    Apcin, a ligand of Cdc20, is a potent and competitive anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity inhibitor. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. Apcin occupes the D-box-binding pocket on the side face of the WD40-domain and can prolong mitosis .
    Apcin
  • HY-125883
    Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc

    Cereblon Ligand-Linker Conjugates 20; E3 Ligase Ligand-Linker Conjugates 53

    		 E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
    Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc

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