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By Targets:	ADC Linker (1) Antibiotic (3) Bacterial (4) CCR (4) Cytochrome P450 (3) Fungal (4) HIV (4) Microtubule/Tubulin (1) NOD-like Receptor (NLR) (1)
By Research Areas:	Cancer (2) Endocrinology (1) Infection (12) Inflammation/Immunology (4)

16

Inhibitors & Agonists

3

Recombinant Proteins

1

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Isavuconazole 3 Publications Verification BaL-4815; RO-0094815	Fungal Cytochrome P450 Antibiotic	Infection
Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.

Isavuconazonium sulfate 1 Publications Verification BaL8557-002	Fungal	Infection
Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis .

Avanbulin BaL27862	Microtubule/Tubulin	Cancer
Avanbulin (BAL27862) is a potent, Colchicine site-binding, tubulin assembly inhibitor. Avanbulin inhibits tubulin assembly at 37 °C with an IC₅₀ of 1.4 μM. Avanbulin binds to tubulin with an apparent K_d value of 244 nM. Avanbulin can be used for the research of cancer and cell division .

BAL-0028	NOD-like Receptor (NLR)	Inflammation/Immunology
BAL-0028 (Compound 3) is a NLRP3 activation inhibitor with a IC₅₀ value of 25 nM. BAL-0028 binds closely to the NACHT domain of the NLRP3 with K_D values of 104-123 nM. BAL-0028 has anti-inflammatory activity .

BAL-30072	Bacterial	Infection
BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC₉₀ values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively .

Isavuconazole-d4 BaL-4815-d₄; RO-0094815-d₄	Fungal Cytochrome P450	Infection
Isavuconazole-d₄ is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi[1].

Ceftobiprole medocaril BaL5788	Bacterial	Infection Inflammation/Immunology
Ceftobiprole medocaril (BAL5788) is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

Ceftobiprole medocaril sodium BaL5788 sodium	Bacterial	Infection Inflammation/Immunology
Ceftobiprole medocaril (BAL5788) sodium is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

Ceftobiprole 2 Publications Verification Ro 63-9141; BaL 9141	Bacterial Antibiotic	Infection Inflammation/Immunology
Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci with a MIC₉₀ value of 2 μg/mL for MRSA. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

HY-160408

Mal-GGG-Bal-NHS ester

ADC Linker Cancer

Mal-GGG-Bal-NHS ester is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Isavuconazole (Standard)	Fungal Cytochrome P450 Antibiotic	Infection
Isavuconazole (Standard) is the analytical standard of Isavuconazole. This product is intended for research and analytical applications. Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.

Aplaviroc AK 602; GSK 873140; GW 873140	CCR HIV	Infection Endocrinology
Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist, with IC₅₀s of 0.1-0.4 nM for HIV-1_Ba-L, HIV-1_JRFL and HIV-1_MOKW.

Aplaviroc hydrochloride AK602 hydrochloride; GSK-873140 hydrochloride; GW-873140 hydrochloride	CCR HIV	Infection
Aplaviroc (AK 602) hydrochloride, a SDP derivative, is a CCR5 antagonist, with IC₅₀s of 0.1-0.4 nM for HIV-1_Ba-L, HIV-1_JRFL and HIV-1_MOKW.

HY-152131

CCR5 antagonist 2

CCR HIV Infection

CCR5 antagonist 2 (Compound 25) is a CCR5 antagonist with an IC₅₀ of 8.34 nM. CCR5 antagonist 2 shows broad-spectrum anti-HIV-1 activities .
HY-152132

CCR5 antagonist 3

CCR HIV Infection

CCR5 antagonist 3 (Compound 26) is a CCR5 antagonist with an IC₅₀ of 15.90 nM. CCR5 antagonist 3 shows broad-spectrum anti-HIV-1 activities .

MFN2 agonist-1	Others	Others
MFN2 agonist-1 (B-A/l) potently stimulates mitochondrial fusion in mitofusin 2 (MFN2)-deficient cells. MFN2 agonist-1 reverses mitochondrial “clumping” (formation of static mitochondrial aggregates) and restores mitochondrial motility in cultured mouse neurons expressing the CMT2A mutant MFN2 T105M.

Species:	Human (2) Mouse (1)
Tag:	His (2) Tag Free (1)
Source:	Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

	Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His) Bile salt-activated lipase; BaL; BSSL; Cel; Lip1	Mouse	Sf9 insect cells
	Carboxyester lipase/CEL protein plays a crucial role in cellular processes as it catalyzes the hydrolysis of a variety of substrates, including cholesterol esters, phospholipids, lysophospholipids, diacylglycerols and triacylglycerols, and lipids of hydroxy fatty acids acid ester. FAHF). Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His) is the recombinant mouse-derived Carboxyl Ester Lipase/CEL protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His) is 534 a.a., with molecular weight of ~133.9 & 59.1 kDa, respectively.

	DTX3L Protein, Human DTX3L; E3 ubiquitin-protein ligase DTX3L; B-lymphoma- and BaL-associated protein; Protein deltex-3-like; RING-type E3 ubiquitin transferase DTX3L; Rhysin-2; Rhysin2	Human	E. coli
	DTX3L protein is an E3 ubiquitin protein ligase that cooperates with PARP9 in DNA damage repair and antiviral responses. It monoubiquitylates histones (H2A, H2B, H3, H4), especially “Lys-91” of H4, possibly signaling additional modifications. DTX3L Protein, Human is the recombinant human-derived DTX3L protein, expressed by E. coli , with tag free. The total length of DTX3L Protein, Human is 739 a.a., .

	DTX3L Protein, Human (His) DTX3L; E3 ubiquitin-protein ligase DTX3L; B-lymphoma- and BaL-associated protein; Protein deltex-3-like; RING-type E3 ubiquitin transferase DTX3L; Rhysin-2; Rhysin2	Human	E. coli
	DTX3L protein is an E3 ubiquitin protein ligase that cooperates with PARP9 in DNA damage repair and antiviral responses. It monoubiquitylates histones (H2A, H2B, H3, H4), especially “Lys-91” of H4, possibly signaling additional modifications. DTX3L Protein, Human (His) is the recombinant human-derived DTX3L protein, expressed by E. coli , with N-6*His labeled tag. The total length of DTX3L Protein, Human (His) is 739 a.a., .

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