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Results for "

CABS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) Bacterial (3) Biochemical Assay Reagents (1) Potassium Channel (3) Proton Pump (4) Small Interfering RNA (siRNA) (3) TAM Receptor (1)
By Research Areas:	Cancer (1) Endocrinology (5) Infection (1) Metabolic Disease (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*P-CAB* agent 2**	Potassium Channel	Endocrinology
P-CAB agent 2 is a potent and orally active potassium-competitive acid blocker and a gastric acid secretion inhibitor. P-CAB agent 2 inhibits H ⁺/K ⁺-ATPase activity with an IC₅₀ value of <100 nM. P-CAB agent 2 inhibits the hERG potassium channel with an IC₅₀ value of 18.69 M. P-CAB agent 2 shows no acute toxicity and inhibits histamine (HY-B1204)-induced gastric acid secretion .

*P-CAB* agent 2 hydrochloride**	Potassium Channel	Endocrinology
P-CAB agent 2 hydrochloride is a potent and orally active potassium-competitive acid blocker and a gastric acid secretion inhibitor. P-CAB agent 2 hydrochloride inhibits H ⁺/K ⁺-ATPase activity with an IC₅₀ value of <100 nM. P-CAB agent 2 hydrochloride inhibits the hERG potassium channel with an IC₅₀ value of 18.69 M. P-CAB agent 2 hydrochloride shows no acute toxicity and inhibits histamine (HY-B1204)-induced gastric acid secretion .

*CABS*	Biochemical Assay Reagents	Others
CABS is a zwitterionic piperazine buffer reagent, which can be used as a buffer reagent for wetting agents, pesticide emulsifiers, and dispersants, and has been used in fluorescent dyeing applications .

CABS1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CABS1 Human Pre-designed siRNA Set A contains three designed siRNAs for CABS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CABS1 Human Pre-designed siRNA Set A CABS1 Human Pre-designed siRNA Set A

*P-CAB* agent 1**	Potassium Channel	Others
P-CAB agent 1 (compound B19) is a highly potent potassium-competitive acid blocker agent with an IC₅₀ value of 60.50 nM for H ⁺/K ⁺-ATPase. P-CAB agent 1 has acceptable oral absorption in rats. P-CAB agent 1 can be used for researching acid-related disorders (ARDs) .

CAB39 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CAB39 Human Pre-designed siRNA Set A contains three designed siRNAs for CAB39 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CAB39 Human Pre-designed siRNA Set A CAB39 Human Pre-designed siRNA Set A

CAB39L Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CAB39L Human Pre-designed siRNA Set A contains three designed siRNAs for CAB39L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CAB39L Human Pre-designed siRNA Set A CAB39L Human Pre-designed siRNA Set A

Mecbotamab BA301	ADC Antibody TAM Receptor	Cancer
Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011) .

Vonoprazan Fumarate 4 Publications Verification TAK-438	Proton Pump	Metabolic Disease
Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H ⁺,K ⁺-ATPase activity in porcine gastric microsomes with an IC₅₀ of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease .

Vonoprazan hydrochloride TAK-438 hydrochloride	Proton Pump Bacterial	Infection Endocrinology
Vonoprazan hydrochloride, a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan hydrochloride inhibits H ⁺,K ⁺-ATPase activity in porcine gastric microsomes with an IC₅₀ of 19 nM at pH 6.5. Vonoprazan hydrochloride is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan hydrochloride can be used for eradication of Helicobacter pylori .

Vonoprazan 4 Publications Verification TAK-438 free base	Proton Pump Bacterial	Endocrinology
Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan inhibits H ⁺,K ⁺-ATPase activity in porcine gastric microsomes with an IC₅₀ of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori .

Vonoprazan (Standard)	Proton Pump Bacterial	Endocrinology
Vonoprazan (Standard) is the analytical standard of Vonoprazan. This product is intended for research and analytical applications. Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan inhibits H ⁺,K ⁺-ATPase activity in porcine gastric microsomes with an IC₅₀ of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori .

*CABS*	Buffer Reagents
CABS is a zwitterionic piperazine buffer reagent, which can be used as a buffer reagent for wetting agents, pesticide emulsifiers, and dispersants, and has been used in fluorescent dyeing applications .

Mecbotamab BA301	ADC Antibody TAM Receptor	Cancer
Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011) .

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