DON

By Targets:	Antibiotic (1) Bacterial (1) Drug Metabolite (1) Endogenous Metabolite (2) Fungal (1) Glutaminase (2) Influenza Virus (1) Isotope-Labeled Compounds (1) Liposome (1) NF-κB (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Infection (2) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108357

6-Diazo-5-oxo-L-nor-Leucine 5+ Cited Publications L-6-Diazo-5-oxonorleucine; DON	Glutaminase Bacterial Influenza Virus Antibiotic	Infection Cancer
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .

HY-122218

JHU-083 4 Publications Verification	Glutaminase	Neurological Disease
JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b ⁺ cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .

HY-N11678

Deoxynivalenol-3-β-D-glucoside DON-3-β-D-glucoside; Deoxynivalenol 3-glucoside	Drug Metabolite	Metabolic Disease
Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .

HY-153151

*Fmoc-DON-Boc*	Others	Cancer
Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist .

HY-N1057

Plantarenaloside

Yuheinoside

Plantarenaloside is an iridoid glucoside that can be isolated from Leucocarpus perfoliatus G. DON .
HY-N3371

Longikaurin E

(-)-Longikaurin E
Others Others

Longikaurin E is a diterpenoids compound isolated from the leaves of Rabdosia ternifolia (D. Don) .
HY-N7521

Procyanidin C2

Procyanidine C2
Others Others

Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .

Plantarenaloside Yuheinoside
Plantarenaloside is an iridoid glucoside that can be isolated from Leucocarpus perfoliatus G. DON .

Longikaurin E (-)-Longikaurin E	Others	Others
Longikaurin E is a diterpenoids compound isolated from the leaves of Rabdosia ternifolia (D. Don) .

Procyanidin C2 Procyanidine C2	Others	Others
Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .

HY-N6685

3-Acetyldeoxynivalenol	Others	Cardiovascular Disease
3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-N1623

1-Hydroxy-2,3,4,7-tetramethoxyxanthone	Endogenous Metabolite	Metabolic Disease
1-Hydroxy-2,3,4,7-tetramethoxyxanthone is a metabolite of xanthone that can be found in Halenia elliptica D. Don .

HY-N11484

5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside	Others	Others
5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside is a natural product that can be isolated from the root of Scutellaria repens Buch.-Ham. ex D. Don .

HY-N3706

Dehydro-α-lapachone	Fungal	Infection
Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC₅₀ value 0.41 mg/L .

HY-N6685S1

3-Acetyldeoxynivalenol-13C17	Isotope-Labeled Compounds	Cardiovascular Disease
3-Acetyldeoxynivalenol- ¹³C₁₇ is the ¹³C labeled 3-Acetyldeoxynivalenol (HY-N6685) . 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-N3552

Catalposide	NF-κB	Inflammation/Immunology
Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages .

HY-128775

JHU395	Others	Cancer
JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST .

HY-W099547

Dihexadecyl hydrogen phosphate	Liposome	Others
Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids. It's often used as an emulsifier, which means it helps mix two substances together that don't usually mix well, such as oil and water. Dihexadecyl hydrogen phosphateIt has several applications in the food industry, especially in the production of processed foods where it improves texture and stability. Additionally, it has applications in the pharmaceutical industry where it can be used ain the generation of micelles, liposomes, and other types of artificial membranes.

HY-155535

17β-HSD10-IN-2	Endogenous Metabolite	Neurological Disease
17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor，targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)，a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer .

Cat. No.	Product Name	Type

HY-W099547

Dihexadecyl hydrogen phosphate	Biochemical Assay Reagents
Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids. It's often used as an emulsifier, which means it helps mix two substances together that don't usually mix well, such as oil and water. Dihexadecyl hydrogen phosphateIt has several applications in the food industry, especially in the production of processed foods where it improves texture and stability. Additionally, it has applications in the pharmaceutical industry where it can be used ain the generation of micelles, liposomes, and other types of artificial membranes.

Dihexadecyl hydrogen phosphate

Biochemical Assay Reagents

Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids. It's often used as an emulsifier, which means it helps mix two substances together that don't usually mix well, such as oil and water. Dihexadecyl hydrogen phosphateIt has several applications in the food industry, especially in the production of processed foods where it improves texture and stability. Additionally, it has applications in the pharmaceutical industry where it can be used ain the generation of micelles, liposomes, and other types of artificial membranes.

Cat. No.	Product Name	Target	Research Area

HY-P99176

ATG-031 1 Publications Verification	Inhibitory Antibodies	Cancer
ATG-031 is a humanised anti-CD24 monoclonal antibody. ATG-031 effectively stimulates macrophage-mediated phagocytosis and induces cancer cell destruction by blocking the "don't eat me" signals that characterize the growth of many cancers. ATG-031 can be used in the study of haematological malignancies as well as solid tumours.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N11678

Deoxynivalenol-3-β-D-glucoside DON-3-β-D-glucoside; Deoxynivalenol 3-glucoside	Structural Classification Natural Products Microorganisms Source classification	Drug Metabolite
Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .

HY-N3371

Longikaurin E (-)-Longikaurin E	Artemisia selengensis Turcz. ex Bess. Classification of Application Fields Terpenoids Labiatae Source classification Other Diseases Diterpenoids Plants Disease Research Fields	Others
Longikaurin E is a diterpenoids compound isolated from the leaves of Rabdosia ternifolia (D. Don) .

HY-N7521

Procyanidin C2 Procyanidine C2	Structural Classification Polygonaceae Source classification Phenols Polyphenols Fagopyrum dibotrys (D. Don) Hara Plants	Others
Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .

HY-N6685

3-Acetyldeoxynivalenol	Cardiovascular Disease Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Others
3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-N1623

1-Hydroxy-2,3,4,7-tetramethoxyxanthone	Structural Classification Halenia elliptica D. Don Flavonoids Xanthones Source classification Gentianaceae Phenols Plants	Endogenous Metabolite
1-Hydroxy-2,3,4,7-tetramethoxyxanthone is a metabolite of xanthone that can be found in Halenia elliptica D. Don .

HY-N11484

5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside	Structural Classification Flavonoids Scutellaria baicalensis Georgi Flavones Labiatae Source classification Plants	Others
5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside is a natural product that can be isolated from the root of Scutellaria repens Buch.-Ham. ex D. Don .

HY-N3706

Dehydro-α-lapachone	Structural Classification Natural Products Catalpa ovata G. Don Source classification Plants Bignoniaceae	Fungal
Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC₅₀ value 0.41 mg/L .

HY-N3552

Catalposide	Other Terpenoids Catalpa ovata G. Don Monophenols Classification of Application Fields Terpenoids Source classification Phenols Plants Bignoniaceae Disease Research Fields Inflammation/Immunology	NF-κB
Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages .

HY-155535

17β-HSD10-IN-2	Structural Classification Monophenols Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor，targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)，a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer .

Cat. No.	Compare	Product Name	Species	Source

HY-P74682

	Neuregulin-2/NRG2 Protein, Human (HEK293, His) Pro-neuregulin-2; Pro-NRG2; Neuregulin-2; DON-1; NTAK; NRG-2	Human	HEK293
	Neuregulin-2/NRG2 protein serves as a direct ligand for the ERBB3 and ERBB4 tyrosine kinase receptors, initiating ligand-stimulated tyrosine phosphorylation and activation of these receptors. At the same time, NRG2 simultaneously recruits ERBB1 and ERBB2 coreceptors, possibly promoting heterodimerization with the EGF receptor. Neuregulin-2/NRG2 Protein, Human (HEK293, His) is the recombinant human-derived Neuregulin-2/NRG2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Neuregulin-2/NRG2 Protein, Human (HEK293, His) is 293 a.a., with molecular weight of ~34 kDa.


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-N6685S1

3-Acetyldeoxynivalenol-13C17
3-Acetyldeoxynivalenol- ¹³C₁₇ is the ¹³C labeled 3-Acetyldeoxynivalenol (HY-N6685) . 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

DON

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Natural
Products