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Results for "

Diosgenin

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Biochemical Assay Reagents

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0177
    Diosgenin
    4 Publications Verification

    		 STAT MicroRNA Metabolic Disease
    Diosgenin, a steroidal saponin, can inhibit STAT3 signaling pathway . Diosgenin is an exogenous activator of Pdia3/ERp57 . Diosgenin inhibits aortic atherosclerosis progression by suppressing macrophage miR-19b expression .
    <em>Diosgenin</em>
  • HY-N0730
    Diosgenin glucoside

    		Autophagy Apoptosis Neurological Disease Inflammation/Immunology
    Diosgenin glucoside, a saponin compound extracted from Trillium tschonoskii, provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis .
    <em>Diosgenin</em> glucoside
  • HY-137179
    Glyco-diosgenin

    		Biochemical Assay Reagents Others
    Glyco-diosgenin is a synthetic surfactant and detergent for extracting proteins from membranes for structure and function studies, and single-particle cryo-electron microscopy (cryoEM) studies of membrane proteins .
    Glyco-<em>diosgenin</em>
  • HY-W145687
    Diosgenin-3-O-β-D-sodium glucuronide

    Diosgenin-3-O-Β-D-glucuronide

    		 Biochemical Assay Reagents Others
    Diosgenin-3-O-β-D-sodium glucuronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    <em>Diosgenin</em>-3-O-β-D-sodium glucuronide
  • HY-N12002
    Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside

    		Others Others
    Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside (compound 9) is a steroidal saponin, which can be obtained from Paris polyphylla var., Yunnan pine (yunnanensis) Isolated .
    <em>Diosgenin</em>-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside
  • HY-151286
    Antitumor agent-73

    		STAT Cancer
    Antitumor agent-73 is a Diosgenin (HY-N0177) derivative, which inhibits STAT3 signaling and activates Pdia3/ERp57 exogenously. Antitumor agent-73 shows potent anti-tumor activity against various cancer cell lines, 7.9-341.7-fold stronger than Diosgenin .
    Antitumor agent-73
  • HY-147538
    Antitumor agent-64

    		Apoptosis Cancer
    Antitumor agent-64 (Compound 8d) is a diosgenin derivative. Antitumor agent-64 exhibits potent cytotoxic activity against A549 cell line. Antitumor agent-64 induces A549 cells apoptosis via the mitochondria-related pathway .
    Antitumor agent-64
  • HY-N2389
    Formosanin C
    1 Publications Verification

    		 Apoptosis Cancer
    Formosanin C is a diosgenin saponin isolated from Paris polyphylla and an immunomodulator with antitumor activity. Formosanin C induces apoptosis .
    Formosanin C
  • HY-N2078
    Yamogenin

    NeoDiosgenin

    		 LXR Metabolic Disease
    Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes .
    Yamogenin

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