Search Result
Results for "
Ginsenoside
" in MedChemExpress (MCE) Product Catalog:
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N4262
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Others
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Others
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Ginsenoside Rh7 is a minor saponin isolated from the leaves of Panax ginseng .
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- HY-N6580
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Bacterial
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Infection
Metabolic Disease
Inflammation/Immunology
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Ginsenoside Rg4 is a major protopanaxatriol type ginsenoside isolated from the leaves of Panax ginseng C. A. Meyer. The protopanaxatriol type ginsenosides (such as Ginsenoside Rg4) exhibits various biological activities including anti-septic, anti-diabetic, wound healing, immune-stimulatory, and anti-antioxidant activity .
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- HY-N12015
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Ginsenoside IV
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Others
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Others
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Ginsenoside Ra6 (Ginsenoside IV) is a panaxadiol-type ginsenoside that can be isolated from the roots of ginseng .
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- HY-N12365
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Others
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Others
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Ginsenoside Rs2 is extracted from Panax ginseng root .
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- HY-N12366
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Others
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Others
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Ginsenoside Rs1 is extracted from Panax ginseng root .
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- HY-N0044
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- HY-N12516
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Others
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Cancer
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Ginsenoside Mc is a natural product, that can be prepared by removal of two glucose molecules at 3-C of ginsenoside Rc (HY-N0042). Ginsenoside Mc has anti-tumor activity .
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- HY-N0606
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Keap1-Nrf2
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Inflammation/Immunology
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Ginsenoside Rh3 is a bacterial metabolite of Ginsenoside Rg5. Ginsenoside Rh3 treatment in human retinal cells induces Nrf2 activation.
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- HY-N0040
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- HY-N0044R
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Ginsenoside B2(Standard); Panaxoside Re(Standard); Sanchinoside Re (Standard)
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Amyloid-β
NF-κB
JNK
Endogenous Metabolite
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Neurological Disease
Inflammation/Immunology
Cancer
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Ginsenoside Re (Standard) is the analytical standard of Ginsenoside Re. This product is intended for research and analytical applications. Ginsenoside Re (Ginsenoside B2) is an extract from Panax notoginseng. Ginsenoside Re decreases the β-amyloid protein (Aβ). Ginsenoside Re plays a role in antiinflammation through inhibition of JNK and NF-κB.
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- HY-N0904R
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Ginsenoside compound K(Standard); Ginsenoside K (Standard)
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COX
NO Synthase
Cytochrome P450
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Inflammation/Immunology
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Ginsenoside C-K (Standard) is the analytical standard of Ginsenoside C-K. This product is intended for research and analytical applications. Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
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- HY-N0605R
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20(S)-Ginsenoside Rh2(Standard); 20(S)-Rh2(Standard); Ginsenoside-Rh2 (Standard)
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Caspase
Apoptosis
Endogenous Metabolite
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Cancer
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Ginsenoside Rh2 (Standard) is the analytical standard of Ginsenoside Rh2. This product is intended for research and analytical applications. Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner.
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- HY-N0598
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20(S)-Ginsenoside F1
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Cytochrome P450
Endogenous Metabolite
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Cancer
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Ginsenoside F1, an enzymatically modified derivative of Ginsenoside Rg1, demonstrates competitive inhibition of CYP3A4 activity and weaker inhibition of CYP2D6 activity.
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- HY-N0605
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20(S)-Ginsenoside Rh2; 20(S)-Rh2; Ginsenoside-Rh2
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Caspase
Apoptosis
Endogenous Metabolite
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Cancer
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Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner.
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- HY-125848
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- HY-N0601
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- HY-N0042
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- HY-N0904
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Ginsenoside compound K; Ginsenoside K
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COX
NO Synthase
Cytochrome P450
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Inflammation/Immunology
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Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
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- HY-N0907
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- HY-N0906
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- HY-N4260
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- HY-125570
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Apoptosis
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Cancer
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Ginsenoside Rs3 is a natural diol-type ginseng saponin with anticancer effects. Ginsenoside Rs3 selectively elevates protein levels of p53 and p21WAF1 leading to induction of apoptosis in SK-HEP-1 cells .
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- HY-N0908
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IGF-1R
NF-κB
COX
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Cardiovascular Disease
Inflammation/Immunology
Endocrinology
Cancer
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Ginsenoside Rg5 is the main component of Red ginseng and IGF-1R agonist. Ginsenoside Rg5 compets for the binding site of IGF-1R and blocks the binding of IGF-1 to IGF-1R (IC50 about 90 nM). Ginsenoside Rg5 also inhibits the mRNA expression of COX-2 via suppression of the DNA binding activities of NF-κB p65.
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- HY-N0041R
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Gypenoside IV (Standard)
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NF-κB
COX
NO Synthase
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Inflammation/Immunology
Cancer
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Ginsenoside Rb3 (Standard) is the analytical standard of Ginsenoside Rb3. This product is intended for research and analytical applications. Ginsenoside Rb3 is extracted from steamed Panax ginseng C. A. Meyer. Ginsenoside Rb3 exhibits inhibitory effect on TNFα-induced NF-κB transcriptional activity with an IC50 of 8.2 μM in 293T cell lines. Ginsenoside Rb3 also inhibits the induction of COX-2 and iNOS mRNA.
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- HY-N2516
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- HY-N0041
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Gypenoside IV
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NF-κB
COX
NO Synthase
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Inflammation/Immunology
Cancer
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Ginsenoside Rb3 is extracted from steamed Panax ginseng C. A. Meyer. Ginsenoside Rb3 exhibits inhibitory effect on TNFα-induced NF-κB transcriptional activity with an IC50 of 8.2 μM in 293T cell lines. Ginsenoside Rb3 also inhibits the induction of COX-2 and iNOS mRNA.
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- HY-N2515
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NF-κB
PI3K
JAK
Apoptosis
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Inflammation/Immunology
Cancer
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Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures .
Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB .
Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis .
Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking PI3K/Akt pathway .
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- HY-N0039R
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Gypenoside III (Standard)
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Na+/K+ ATPase
IRAK
NF-κB
Autophagy
Mitophagy
HSV
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Inflammation/Immunology
Cancer
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Ginsenoside Rb1 (Standard) is the analytical standard of Ginsenoside Rb1. This product is intended for research and analytical applications. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na +, K +-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .
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- HY-N0043R
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Gypenoside VIII (Standard)
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NF-κB
COX
Calcium Channel
Cytochrome P450
Endogenous Metabolite
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Cardiovascular Disease
Inflammation/Immunology
Cancer
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Ginsenoside Rd (Standard) is the analytical standard of Ginsenoside Rd. This product is intended for research and analytical applications. Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca 2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.
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- HY-N4259
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- HY-N0043
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- HY-N2503
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Apoptosis
MMP
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Inflammation/Immunology
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Ginsenoside F4 (GF4), ginseng saponinis, isolated from notoginseng or red ginseng. Ginsenoside F4 (GF4) has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis .
Ginsenoside F4 (GF4) inhibits matrix metalloproteinase 13 (MMP 13) expression in IL-1β-treated chondrocytes and blocks cartilage breakdown in rabbit cartilage tissue culture, shows therapeutic potential for preventing cartilage collagen matrix breakdown in diseased tissues .
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- HY-N2504
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- HY-N0045
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- HY-N0039
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- HY-N2506
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Others
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Cardiovascular Disease
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Ginsenoside Ra1 is a component from ginseng, inhibits protein tyrosine kinase (PTK) activation induced by hypoxia/reoxygenation .
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- HY-N0045R
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Panaxoside A (Standard); Panaxoside Rg1 (Standard)
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Amyloid-β
NF-κB
Apoptosis
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Neurological Disease
Inflammation/Immunology
Cancer
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Ginsenoside Rg1 (Standard) is the analytical standard of Ginsenoside Rg1. This product is intended for research and analytical applications. Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.
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- HY-108277
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Apoptosis
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Cancer
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Ginsenoside F5, from crude extracts of flower buds of Panax ginseng, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway .
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- HY-N0602
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Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2
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NF-κB
Amyloid-β
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Cardiovascular Disease
Neurological Disease
Cancer
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Ginsenoside Rg2 is one of the major active components of ginseng. Ginsenoside Rg2 inhibits VCAM-1 and ICAM-1 expressions stimulated with lipopolysaccharide (LPS). Ginsenoside Rg2 also reduces Aβ1-42 accumulation.
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- HY-N0602R
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Chikusetsusaponin I(Standard); Panaxoside Rg2(Standard); Prosapogenin C2 (Standard)
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NF-κB
Amyloid-β
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Cardiovascular Disease
Neurological Disease
Cancer
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Ginsenoside Rg2 (Standard) is the analytical standard of Ginsenoside Rg2. This product is intended for research and analytical applications. Ginsenoside Rg2 is one of the major active components of ginseng. Ginsenoside Rg2 inhibits VCAM-1 and ICAM-1 expressions stimulated with lipopolysaccharide (LPS). Ginsenoside Rg2 also reduces Aβ1-42 accumulation.
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- HY-N0167
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- HY-N0600
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Interleukin Related
IFNAR
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Inflammation/Immunology
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Ginsenoside F3, a component of PPTGs (an minor saponin in the leaves of Panax ginseng), has immunoenhancing activity by regulating production and gene expression of type 1 cytokines (IL-2, IFN-gamma) and type 2 cytokines (IL-4 and IL-10) .
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- HY-N0604R
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Prosapogenin A2 (Standard); Sanchinoside B2 (Standard); Sanchinoside Rh1 (Standard)
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PPAR
TNF Receptor
Interleukin Related
Endogenous Metabolite
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Inflammation/Immunology
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Ginsenoside Rh1 (Standard) is the analytical standard of Ginsenoside Rh1. This product is intended for research and analytical applications. Ginsenoside Rh1 (Prosapogenin A2) inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.
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- HY-N0607
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Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V
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Calcium Channel
Prostaglandin Receptor
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Cardiovascular Disease
Endocrinology
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Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) exhibits a Ca 2+-antagonistic antiplatelet effect with an IC50 of 155 μM. Ginsenoside Ro reduces the production of TXA2 more than it reduces the activities of COX-1 and TXAS.
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- HY-N0541
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Ginsenoside A1
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Endogenous Metabolite
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Others
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Pseudoginsenoside F11 (Ginsenoside A1), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice.
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- HY-N0604
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- HY-N0046
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Notoginseng triterpenes; Ginsenoside Mb
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Others
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Others
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Notoginsenoside Fe is a natural compound isolated from Panax pseudo-ginseng.
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- HY-N0909
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20(S)-NotoGinsenoside R2; Ginsenoside Ng-R2
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Apoptosis
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Neurological Disease
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Notoginsenoside R2 is a newly isolated notoginsenoside from Panax notoginseng, showed neuroprotective effects against 6-OHDA-induced oxidative stress and apoptosis.
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- HY-N1400
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Others
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Cancer
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(20R)-Ginsenoside Rh1, the R isomer of Ginsenoside Rh1 isolated from Panax Ginseng, inhibits the thrombin-induced conversion of fibrinogen to fibrin .
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- HY-N0603R
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20(S)-Propanaxadiol(Standard); S-Ginsenoside Rg3 (Standard)
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Sodium Channel
Potassium Channel
NF-κB
COX
Amyloid-β
Endogenous Metabolite
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Neurological Disease
Inflammation/Immunology
Cancer
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20(S)-Ginsenoside Rg3 (Standard) is the analytical standard of 20(S)-Ginsenoside Rg3. This product is intended for research and analytical applications. 20(S)-Ginsenoside Rg3 is the main component of Panax ginseng C. A. Meyer. Ginsenoside Rg3 inhibits Na + and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. 20(S)-Ginsenoside Rg3 also inhibits Aβ levels, NF-κB activity, and COX-2 expression.
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- HY-N0603
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- HY-N1401
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MMP
Apoptosis
HSV
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Infection
Inflammation/Immunology
Cancer
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20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis, and has anti-inflammatory and antioxidative activity . 20(R)-Ginsenoside Rh2 inhibits the replication and proliferation of mouse and human gammaherpesvirus 68 (MHV-68) with an IC50 of 2.77 μM for murine MHV-68 .
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- HY-N8901
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- HY-N8030
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Others
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Others
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Pseudoginsenoside Rg3 (compound 8) is the product of ginsenoside Rb1 fermentation with Acremonium strictum AS 3.2058 .
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- HY-N10336
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Others
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Others
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Notoginsenoside R4 is a ginsenoside that can be isolated from ginseng roots .
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- HY-N1376
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(20R)-Propanaxadiol; R-Ginsenoside Rg3
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Others
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Cancer
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(20R)-ginsenoside Rg3 ((20R)-Propanaxadiol), one of the active compounds present in ginseng root, inhibits angiogenesis, and has anti-carcinogenic and antimetastatic effects .
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- HY-N2039
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Others
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Cancer
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20(R)-Ginsenoside Rg2 shows inhibitory effects on lung cancer NCI-H1650 cells. Anti-cancer activities .
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- HY-N7678
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Others
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Cancer
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Gypenoside LXXV, isolated from Gynostemma pentaphyllum, is one of the deglycosylated shapes of ginsenoside Rb1. Gypenoside LXXV significantly reduces cancer cell viability and displays an anti-cancer effect .
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- HY-N7954
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Others
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Neurological Disease
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Neopanaxadiol, an aglycone of protopanaxadiol type ginsenosides, has the potential for Alzheimer's disease research .
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- HY-125825
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Others
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Cancer
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Pseudoginsenoside Rh2, synthesized from Ginsenoside Rh2, possesses anti-cancer activitied .
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- HY-N0798
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20(R)-APPT
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Others
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Others
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20(R)-Protopanaxatriol is a natural aglycone of ginsenosides Re, Rf, Rg1, Rg2 and Rh.
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- HY-125825A
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Others
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Cancer
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(Z)-Pseudoginsenoside Rh2 is the (Z) isoform of Pseudoginsenoside Rh2 (HY-125825), which is synthesized from Ginsenoside Rh2, possesses anti-cancer activitied .
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- HY-N2040
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Bacterial
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Infection
Cancer
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(20R)-Protopanaxadiol is a triterpenoid saponin metabolite of 20(R)-ginsenoside Rg3 in black ginseng. (20R)-Protopanaxadiol exhibits anti-tumor activity and cytotoxicity, and potently inhibits the growth of Helicobacter pylori .
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- HY-N0835
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- HY-146105
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Apoptosis
MDM-2/p53
MMP
Bcl-2 Family
Reactive Oxygen Species
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Cancer
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Anticancer agent 65 (compound 4c) shows excellent activity in cancer cell lines, especially A549 cells, with an IC50 of 1.07 μM. Anticancer agent 65 induces S-phase arrest in A549 cells and increases the expression level of p53 and p21. Anticancer agent 65 causes apoptosis, ROS generation and collapse of MMP in A549 cells .
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- HY-146419
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NF-κB
COX
TNF Receptor
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Inflammation/Immunology
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Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation .
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