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Results for "

PAF-AH

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Phospholipase (4) Small Interfering RNA (siRNA) (4)
By Research Areas:	Cancer (1) Metabolic Disease (4) Neurological Disease (4)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-RS09970

PAFAH2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PAFAH2 Human Pre-designed siRNA Set A contains three designed siRNAs for PAFAH2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PAFAH2 Human Pre-designed siRNA Set A PAFAH2 Human Pre-designed siRNA Set A

HY-RS09968

PAFAH1B2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PAFAH1B2 Human Pre-designed siRNA Set A contains three designed siRNAs for PAFAH1B2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PAFAH1B2 Human Pre-designed siRNA Set A PAFAH1B2 Human Pre-designed siRNA Set A

HY-RS09969

PAFAH1B3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PAFAH1B3 Human Pre-designed siRNA Set A contains three designed siRNAs for PAFAH1B3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PAFAH1B3 Human Pre-designed siRNA Set A PAFAH1B3 Human Pre-designed siRNA Set A

HY-RS09967

PAFAH1B1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PAFAH1B1 Human Pre-designed siRNA Set A contains three designed siRNAs for PAFAH1B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PAFAH1B1 Human Pre-designed siRNA Set A PAFAH1B1 Human Pre-designed siRNA Set A

HY-142669

Lp-PLA2-IN-4	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-4 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-4 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 38) .

HY-142670

Lp-PLA2-IN-5	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-5 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-5 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 32) .

HY-142779

Lp-PLA2-IN-11	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-11 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2014114249A1, compound E145) .

HY-142778

Lp-PLA2-IN-10	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-10 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-10 has the potential for the research of neurodegenerative-related diseases such as Alzheimer's disease (AD), glaucoma, age-related macular degeneration (AMD), or cardiovascular diseases including atherosclerosis (extracted from patent WO2022001881A1, compound 4) .

HY-111053

P11	Others	Cancer
P11 is a selective inhibitor of platelet-activating factor acetylhydrolases (PAFAHs) 1b2 and 1b3 that impairs cancer cell survival. P11 exhibits IC₅₀ values of ~40 and 900 nM for PAFAH1b2 and 1b3, respectively .

Species:	Human (1) Mouse (2)
Tag:	His (3) Myc (2)
Source:	HEK293 (1) Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P71185

	PAFAHB Protein, Human (His) Platelet-Activating Factor Acetylhydrolase IB Subunit Beta; PAF Acetylhydrolase 30 kDa Subunit; PAF-AH 30 kDa Subunit; PAF-AH Subunit Beta; PAFAH Subunit Beta; PAFAH1B2; PAFAHB	Human	E. coli
	PAFAHB Proteinas, incorporating Alpha-2 adrenergic receptors, facilitates catecholamine-induced adenylate cyclase inhibition through G proteins. Notably, oxymetazoline ranks as the most potent agonist, followed by clonidine and antagonists with yohimbine exhibiting the highest inhibitory activity. This insight into agonist and antagonist effectiveness sheds light on the pharmacological modulation of Alpha-2 adrenergic receptors by ADRA2A-VLPs. PAFAHB Protein, Human (His) is the recombinant human-derived PAFAHB protein, expressed by E. coli , with C-6*His labeled tag. The total length of PAFAHB Protein, Human (His) is 228 a.a., with molecular weight of ~31.0 kDa.

HY-P700568

	PLA2G7 Protein, Mouse (HEK293, N-His, C-Myc) PLA2G7; phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma); platelet-activating factor acetylhydrolase; LDL PLA2; PAFAH; LDL-PLA(2); gVIIA-PLA2; PAF 2-acylhydrolase; PAF acetylhydrolase; group-VIIA phospholipase A2; LDL-associated phospholipase A2; lipoprotein-associated phospholipase A2; 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; PAFAD; LP-PLA2; LDL-PLA2	Mouse	HEK293
	The PLA2G7 protein is a lipoprotein-associated calcium-independent phospholipase A2 that plays a key role in phospholipid catabolism during inflammation and oxidative stress responses. It acts at the lipid-water interface and hydrolyzes the ester bond of the fatty acyl group at the sn-2 position, with particular preference for short-chain fatty acyl groups. PLA2G7 Protein, Mouse (HEK293, N-His, C-Myc) is the recombinant mouse-derived PLA2G7 protein, expressed by HEK293 , with C-Myc, N-10*His labeled tag. The total length of PLA2G7 Protein, Mouse (HEK293, N-His, C-Myc) is 419 a.a., with molecular weight of 51.9 kDa.

HY-P700567

	PLA2G7 Protein, Mouse (Baculovirus, N-His, C-Myc) PLA2G7; phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma); platelet-activating factor acetylhydrolase; LDL PLA2; PAFAH; LDL-PLA(2); gVIIA-PLA2; PAF 2-acylhydrolase; PAF acetylhydrolase; group-VIIA phospholipase A2; LDL-associated phospholipase A2; lipoprotein-associated phospholipase A2; 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; PAFAD; LP-PLA2; LDL-PLA2	Mouse	Sf9 insect cells
	The PLA2G7 protein is a lipoprotein-associated calcium-independent phospholipase A2 that plays a key role in phospholipid catabolism during inflammation and oxidative stress responses. It acts at the lipid-water interface and hydrolyzes the ester bond of the fatty acyl group at the sn-2 position, with particular preference for short-chain fatty acyl groups. PLA2G7 Protein, Mouse (Baculovirus, N-His, C-Myc) is the recombinant mouse-derived PLA2G7 protein, expressed by Sf9 insect cells , with C-Myc, N-10*His labeled tag. The total length of PLA2G7 Protein, Mouse (Baculovirus, N-His, C-Myc) is 419 a.a., with molecular weight of 50.7 kDa.


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