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Results for "

PUFA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (14) Histone Demethylase (2) Isotope-Labeled Compounds (3) Potassium Channel (1) Prostaglandin Receptor (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (10) Inflammation/Immunology (2) Metabolic Disease (12) Neurological Disease (1)

Inhibitors & Agonists

Peptides

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Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-21268

Methyl linolenate 1 Publications Verification Linolenic acid methyl ester	Others	Metabolic Disease
Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-N7140

Gamma-Linolenic acid 2 Publications Verification γ-Linolenic acid	Endogenous Metabolite	Metabolic Disease
Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-121520

Docosahexaenoyl glycine	Potassium Channel Endogenous Metabolite	Cardiovascular Disease
Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs?channels?and restore the function of IKs?channels with LQT1 mutation .

HY-113120

Stearidonic acid 6Z,9Z,12Z,15Z-Octadecatetraenoic acid	Endogenous Metabolite	Others
Stearidonic acid (6Z,9Z,12Z,15Z-Octadecatetraenoic acid) is an intermediate fatty acid in the biosynthetic pathway from α-linolenic acid to VLC ω-3 PUFA. The conversion efficiency of stearidonic acid is higher than that of alpha-linolenic acid. Increasing the intake of stearidonic acid can increase the content of eicosapentaenoic acid (EPA) in red blood cells. Stearidonic acid can also be isolated from methanolic extracts of the brown alga Brachyphyllum gracilis .

HY-147335

6,9,12,15-Hexadecatetraenoic acid-ethyl ester	Others	Cardiovascular Disease
6,9,12,15-Hexadecatetraenoic acid-ethyl ester is an orally active n-1PUFA. 6,9,12,15-Hexadecatetraenoic acid-ethyl ester intake can reduce plasma triglyceride content in mice .

HY-N7140R

Gamma-Linolenic acid (Standard) γ-Linolenic acid (Standard)	Endogenous Metabolite	Metabolic Disease
Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-125770

5(S)-HPETE	Endogenous Metabolite	Inflammation/Immunology
5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs.

HY-134511

15(S)-HpEPE	Prostaglandin Receptor	Inflammation/Immunology Cancer
15(S)-HpEPE is a product of lipoxygenase hydrolysis of unsaturated fatty acids (PUFA) and is a potential inhibitor of prostaglandin H synthase 2 (PGHS-2). 15(S)-HpEPE can downregulate the expression of PGHS-2 .

HY-21268S

Methyl linolenate-13C18	Isotope-Labeled Compounds	Others
Methyl linolenate- ¹³C₁₈ is the ¹³C labeled Methyl linolenate[1]. Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids[2][3]. The IC50 is 60 uM[4].

HY-N0729

Linoleic acid 5+ Cited Publications	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S1

Linoleic acid-d11	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Linoleic acid-d₁₁ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

HY-N0729S

Linoleic acid-d4	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Linoleic Acid-d₄ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

HY-N0729S2

Linoleic acid-13C18	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Linoleic acid- ¹³C₁₈ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

HY-N0729S3

Linoleic acid-13C1	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Linoleic acid- ¹³C₁ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

HY-N0729S5

Linoleic acid-d2 Deulinoleic acid	Endogenous Metabolite	Metabolic Disease
Linoleic Acid-d₂ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S4

Linoleic acid-d5	Isotope-Labeled Compounds	Cardiovascular Disease Metabolic Disease
Linoleic Acid-d₅ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729R

Linoleic acid (Standard)	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
Linoleic acid (Standard) is the analytical standard of Linoleic acid. This product is intended for research and analytical applications. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-B0660

Eicosapentaenoic Acid Maximum Cited Publications 10 Publications Verification EPA; Timnodonic acid	Endogenous Metabolite Histone Demethylase	Neurological Disease Cancer
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-W011269

Eicosapentaenoic Acid sodium EPA sodium; Timnodonic acid sodium	Endogenous Metabolite Histone Demethylase	Cardiovascular Disease Metabolic Disease
Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation .

Docosahexaenoyl glycine	Potassium Channel Endogenous Metabolite	Cardiovascular Disease
Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs?channels?and restore the function of IKs?channels with LQT1 mutation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-21268

Methyl linolenate 1 Publications Verification Linolenic acid methyl ester	Structural Classification Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-N7140

Gamma-Linolenic acid 2 Publications Verification γ-Linolenic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Labiatae Source classification Disease markers Metabolic Disease Espeletia schultzii Wedd. Endocrine diseases Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-121520

Docosahexaenoyl glycine	Cardiovascular Disease Structural Classification Alkaloids Classification of Application Fields Ketones, Aldehydes, Acids Other Alkaloids Source classification Endogenous metabolite Disease Research Fields	Potassium Channel Endogenous Metabolite
Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs?channels?and restore the function of IKs?channels with LQT1 mutation .

HY-113120

Stearidonic acid 6Z,9Z,12Z,15Z-Octadecatetraenoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Stearidonic acid (6Z,9Z,12Z,15Z-Octadecatetraenoic acid) is an intermediate fatty acid in the biosynthetic pathway from α-linolenic acid to VLC ω-3 PUFA. The conversion efficiency of stearidonic acid is higher than that of alpha-linolenic acid. Increasing the intake of stearidonic acid can increase the content of eicosapentaenoic acid (EPA) in red blood cells. Stearidonic acid can also be isolated from methanolic extracts of the brown alga Brachyphyllum gracilis .

HY-N7140R

Gamma-Linolenic acid (Standard) γ-Linolenic acid (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Labiatae Source classification Disease markers Metabolic Disease Espeletia schultzii Wedd. Endocrine diseases Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-125770

5(S)-HPETE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs.

HY-N0729

Linoleic acid 5+ Cited Publications	Cardiovascular Disease Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Biological Pesticide Research Agricultural Research	Endogenous Metabolite
Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729R

Linoleic acid (Standard)	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Biological Pesticide Research Agricultural Research	Endogenous Metabolite
Linoleic acid (Standard) is the analytical standard of Linoleic acid. This product is intended for research and analytical applications. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-B0660

Eicosapentaenoic Acid Maximum Cited Publications 10 Publications Verification EPA; Timnodonic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Histone Demethylase
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-W011269

Eicosapentaenoic Acid sodium EPA sodium; Timnodonic acid sodium	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Histone Demethylase
Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation .

Cat. No.	Product Name	Chemical Structure

HY-N0729S

Linoleic acid-d4
Linoleic Acid-d₄ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Linoleic acid-d4

Linoleic Acid-d₄ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

HY-N0729S2

Linoleic acid-13C18
Linoleic acid- ¹³C₁₈ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Linoleic acid-13C18

Linoleic acid- ¹³C₁₈ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

HY-21268S

Methyl linolenate-13C18
Methyl linolenate- ¹³C₁₈ is the ¹³C labeled Methyl linolenate[1]. Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids[2][3]. The IC50 is 60 uM[4].

HY-N0729S1

Linoleic acid-d11
Linoleic acid-d₁₁ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Linoleic acid-d11

Linoleic acid-d₁₁ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

HY-N0729S3

Linoleic acid-13C1
Linoleic acid- ¹³C₁ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Linoleic acid-13C1

Linoleic acid- ¹³C₁ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

HY-N0729S5

Linoleic acid-d2
Linoleic Acid-d₂ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

Linoleic acid-d2

Linoleic Acid-d₂ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S4

Linoleic acid-d5
Linoleic Acid-d₅ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

Linoleic acid-d5

Linoleic Acid-d₅ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

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