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Results for "

Phaseic acid

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (412) Cardiovascular Disease (19) Infection (29) Inflammation/Immunology (36) Metabolic Disease (10) Neurological Disease (17)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Alkynes (5)

524

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: Amino Acid Derivatives Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-111973

Phaseic acid	Others	Metabolic Disease
Phaseic acid is a Abscisic acid terpenoid catabolite that can able to activate a subset of Abscisic acid repectors. Phaseic acid is a plant hormone associated with photosynthesis arrest and abscission .

HY-77817

Pyrrole-2-carboxaldehyde	Others	Others
Pyrrole-2-carboxaldehyde has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase .

HY-111973S3

Phaseic acid-d4

Isotope-Labeled Compounds Others

Phaseic acid-d₄ is the deuterium labeled Phaseic acid[1].

Phaseic acid-d4	Isotope-Labeled Compounds	Others
Phaseic acid-d₄ is the deuterium labeled Phaseic acid[1].

HY-147913

PI3K/Akt/mTOR-IN-3	PI3K Akt mTOR Apoptosis	Cancer
PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC₅₀ values of 0.77, 1.23, and 4.57μM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the concentration of 4 μM. PI3K/Akt/mTOR-IN-3 induces cell apoptosis and S phase arrest .

HY-155055

Antiproliferative agent-26	Others	Cancer
Antiproliferative agent-26 (compound 4g) is an antiproliferative agent with much broad range of activity targeting Leukemia, CNS, Melanoma, Renal and Breast (at the concentration of 10 μM). Antiproliferative agent-26 inhibits colony forming and arrests cell cycle at G1 phase/S phase at 5 μM and 25 μM, respectively .

HY-D0080

Laurdan 2 Publications Verification	Fluorescent Dye	Others
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase.

HY-160956

Nitto Phase HL UnyLinker 300

Biochemical Assay Reagents Others

Nitto Phase HL UnyLinker 300 is a link support.
HY-D2190

Ag2S Oil phase (1200 nm)

Fluorescent Dye Others

Ag2S Oil phase (1200 nm) is a fluorescent dyes.

*Nitto Phase* HL UnyLinker 300**	Biochemical Assay Reagents	Others
Nitto Phase HL UnyLinker 300 is a link support.

*Ag2S Oil phase* (1200 nm)**	Fluorescent Dye	Others
Ag2S Oil phase (1200 nm) is a fluorescent dyes.

HY-B0615A

Moricizine Hydrochloride EN 313; Ethmozin; Moracizine	Others	Cardiovascular Disease
Moricizine Hydrochloride (EN 313) is an orally active Class I antiarrhythmic agent. Moricizine Hydrochloride decreases the maximum rate of phase 0 depolarization; increases rates of phase 2 and 3 repolarization, decreases action potential duration, and decreases effective refractory period .

HY-131092

H-Asn-Arg-OH

Others Others

H-Asn-Arg-OH is used for the solid-phase peptide synthesis.
HY-W042216

Sodium Sulphanilate

Sodium 4-aminobenzenesulfonate
Others Inflammation/Immunology

Sodium Sulphanilate is a biochemical indice of inflammation-associated acute-phase response .
HY-131094

H-Gly-D-Tyr-OH

Others Others

H-Gly-D-Tyr-OH is used for the the solid-phase peptide synthesis.

H-Asn-Arg-OH	Others	Others
H-Asn-Arg-OH is used for the solid-phase peptide synthesis.

Sodium Sulphanilate Sodium 4-aminobenzenesulfonate	Others	Inflammation/Immunology
Sodium Sulphanilate is a biochemical indice of inflammation-associated acute-phase response .

H-Gly-D-Tyr-OH	Others	Others
H-Gly-D-Tyr-OH is used for the the solid-phase peptide synthesis.

HY-W011052

Tetrapentylammonium bromide	Biochemical Assay Reagents	Others
Tetrapentylammonium bromide is a quaternary ammonium salt consisting of a positively charged tetrapentylammonium cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic synthesis reactions to facilitate the transfer of reactants between immiscible phases. It is also used in the production of surfactants, detergents and the synthesis of pharmaceuticals.

HY-100052

6-Hydroxybentazon

6-Hydroxybentazone
Drug Metabolite Others

6-Hydroxybentazon is a phase I metabolite of bentazone, and bentazone is a chemical for use in herbicides.
HY-115683

NUN82647

QBS
Apoptosis Cancer

NUN82647 inhibits cell cycle at G2 phase and induces apoptosis .

6-Hydroxybentazon 6-Hydroxybentazone	Drug Metabolite	Others
6-Hydroxybentazon is a phase I metabolite of bentazone, and bentazone is a chemical for use in herbicides.

NUN82647 QBS	Apoptosis	Cancer
NUN82647 inhibits cell cycle at G2 phase and induces apoptosis .

HY-N8487

7-Methoxyflavone	Others	Neurological Disease Inflammation/Immunology
7-Methoxyflavone is a compound isolated from Zornia brasiliensis. 7-Methoxyflavone has peripheral antinociceptive activity. 7-Methoxyflavone inhibits paw-licking time in the neurogenic phase of the formalin pain response (65.6%) and did not decrease the nociceptive response in the inflammatory phase .

HY-N6600

Octadecane

Others Others

Octadecane is an alkane that is used to store thermal energy at ambient temperature as a phase change material .
HY-D2196

AgAuSe Oil phase (1120 nm)

Fluorescent Dye Others

AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window.

Octadecane	Others	Others
Octadecane is an alkane that is used to store thermal energy at ambient temperature as a phase change material .

*AgAuSe Oil phase* (1120 nm)**	Fluorescent Dye	Others
AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window.

HY-N1428A

Citric acid monohydrate 2 Publications Verification	Endogenous Metabolite Apoptosis Antibiotic	Metabolic Disease Inflammation/Immunology
Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate causes renal toxicity in mice .

HY-Y1045

Tetrabutylammonium hydrogensulfate TBAHS-MB	Biochemical Assay Reagents	Others
Tetrabutylammonium hydrosulfate is a quaternary ammonium salt that is commonly used as a phase transfer catalyst, acid catalyst and reagent in various chemical reactions, especially in organic synthesis. Tetrabutylammonium hydrosulfate has unique chemical properties that allow it to facilitate the transfer of ions or molecules from one phase to another, making it an important ingredient in a variety of industrial processes.

HY-Y0080

Methyl trioctyl ammonium chloride	Biochemical Assay Reagents	Others
Methyl trioctyl ammonium chloride is a quaternary ammonium salt commonly used as a surfactant, stabilizer and phase transfer catalyst in various chemical reactions, especially in organic synthesis. Methyl trioctyl ammonium chloride has unique chemical properties that facilitate the transfer of ions or molecules from one phase to another, making it an important ingredient in a variety of industrial processes.

HY-115772

4′-Bromoflavone

Others Cancer

4′-Bromoflavone, a cancer chemopreventive agent, is a potent phase II detoxification enzymes inducer .
HY-D2193

AgAuSe Oil phase (1000 nm)

Fluorescent Dye Others

AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .

4′-Bromoflavone	Others	Cancer
4′-Bromoflavone, a cancer chemopreventive agent, is a potent phase II detoxification enzymes inducer .

*AgAuSe Oil phase* (1000 nm)**	Fluorescent Dye	Others
AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .

HY-N0421

Cinobufagin 3 Publications Verification Cinobufagine	Apoptosis	Neurological Disease Cancer
Cinobufagin is an anticancer agent that can be secreted by the Asiatic toad Bufo gargarizans. Cinobufagin induces the cell cycle arrests in the G1 phase or G2/M phase, leading to apoptosis in cancer cells. Cinobufagin inhibits tumor growth in melanoma and glioblastoma multiforme xenograft mouse models .

HY-N1428

Citric acid 3 Publications Verification	Apoptosis Endogenous Metabolite Antibiotic	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

HY-155552

GSPT1 degrader-1	Apoptosis	Cancer
GSPT1 degrader-1 (compound 9q) is a potent degrader of G1 to S phase transition 1 (GSPT1) via ubiquitin-proteasome system. GSPT1 degrader-1 also induces cell G0/G1 phase arrest and apoptosis .

HY-131091

Boc-Glu(OBzl)-OSu

Amino Acid Derivatives Others

Boc-Glu(OBzl)-OSu can be used for the solid-phase peptide synthesis containing glutamate benzyl ester residues.

Boc-Glu(OBzl)-OSu	Amino Acid Derivatives	Others
Boc-Glu(OBzl)-OSu can be used for the solid-phase peptide synthesis containing glutamate benzyl ester residues.

HY-131960

Sucrose-epichlorohydrin copolymer 2 Publications Verification Polysucrose 400	Biochemical Assay Reagents	Others
Sucrose-epichlorohydrin copolymer acts as a macromolecular crowder and promotes protein liquid-liquid phase separation (LLPS) .

HY-B0615AS

Moricizine-d8(Hydrochloride) EN 313-d₈; Ethmozin-d₈; Moracizine-d₈	Isotope-Labeled Compounds	Cardiovascular Disease
Moricizine-d₈ (Hydrochloride) is the deuterium labeled Moricizine Hydrochloride (HY-B0615A). Moricizine Hydrochloride is an orally active Class I antiarrhythmic agent. Moricizine Hydrochloride decreases the maximum rate of phase 0 depolarization; increases rates of phase 2 and 3 repolarization, decreases action potential duration, and decreases effective refractory period[1][2].

HY-B2201

Citric acid trisodium 3 Publications Verification Sodium citrate; Trisodium citrate anhydrous	Apoptosis Endogenous Metabolite	Metabolic Disease
Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice .

HY-W016413

4-(Hydroxymethyl)phenoxyacetic acid

Others Others

4-(Hydroxymethyl)phenoxyacetic acid is an acid-labile resin linkage agent for use in solid phase peptide synthesis .
HY-160198

Vaccine adjuvant-1

Others Infection

Vaccine adjuvant-1 is an vaccine adjuvant is a vaccine adjuvant containing an oil phase, emulsifying agent and water .

4-(Hydroxymethyl)phenoxyacetic acid	Others	Others
4-(Hydroxymethyl)phenoxyacetic acid is an acid-labile resin linkage agent for use in solid phase peptide synthesis .

Vaccine adjuvant-1	Others	Infection
Vaccine adjuvant-1 is an vaccine adjuvant is a vaccine adjuvant containing an oil phase, emulsifying agent and water .

HY-147748

COX-2-IN-17	COX	Inflammation/Immunology
COX-2-IN-17 (compound 10) is a potent and BBB-penetrated COX-2 (cyclooxygenase-2) inhibitor, with an IC₅₀ of 0.02 μM. COX-2-IN-17 shows anti-inflammatory and analgesic activities. COX-2-IN-17 attenuates hyperalgesia in the neurogenic phase as well as the inflammatory phase .

HY-W014408

Tetraethylammonium bromide TEA bromide	Biochemical Assay Reagents	Others
Tetraethylammonium bromide is a quaternary ammonium salt consisting of a positively charged tetraethylammonium cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a reagent for the synthesis of various organic compounds, an electrolyte in electrochemical experiments, and a source of tetraethylammonium ions in biochemical and pharmacological research.

HY-W100404

Tetramethylammonium 4-methylbenzenesulfonate	Biochemical Assay Reagents	Others
Tetramethylammonium p-toluenesulfonate is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is widely used as a phase transfer catalyst in organic synthesis to facilitate the transfer of reactants between immiscible phases. Furthermore, it can be used as a surfactant, emulsifier or stabilizer in various industrial applications. Its unique chemical properties make it an important ingredient in the production of pharmaceuticals, agrochemicals and materials science products.

HY-W105516

N-Benzyl-N,N-dimethylbenzenaminium chloride Phenylbenzyldimethylammonium chloride	Biochemical Assay Reagents	Others
N-Benzyl-N,N-dimethylbenzeneminium chloride is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is widely used as a phase transfer catalyst in organic synthesis to facilitate the transfer of reactants between immiscible phases. In addition, it is used as an emulsifier, surfactant or disinfectant in various industrial applications. Its unique chemical properties make it an important ingredient in the production of pharmaceuticals, agrochemicals and polymer materials.

HY-161067

EGFR-IN-96	EGFR Apoptosis	Cancer
EGFR-IN-96 (compound 7a) is a thieno[2,3-d]pyrimidine EGFR inhibitor that can induce apoptosis. EGFR-IN-96 arrests the growth of HepG2 cells in the S phase and G2/M phase, and inhibits the growth of cancer cells bearing EGFR wild-type and EGFR ^T790M .

HY-Y0801

2,6-Dihydroxybenzoic acid	Endogenous Metabolite	Others
2,6-Dihydroxybenzoic acid is a secondary metabolite of salicylic acid which has been hydrolyzed by liver enzymes during phase I metabolism.

HY-P99954

Rivabazumab pegol

Bacterial Infection

Rivabazumab pegol is a PcrV protein antibody that can be used to study the phase II pegylated Fab of chronic Pseudomonas aeruginosa infection .

Rivabazumab pegol	Bacterial	Infection
Rivabazumab pegol is a PcrV protein antibody that can be used to study the phase II pegylated Fab of chronic Pseudomonas aeruginosa infection .

HY-W017224

Sodium butane-1-sulfonate Sodium 1-butanesulfonate	Biochemical Assay Reagents	Others
Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) can be used as a mobile phase to separate arsenic or selenium compounds .

HY-W011972

Bromocholine bromide	Biochemical Assay Reagents	Others
2-Bromo-N,N,N-trimethylethanaminium bromide is a quaternary ammonium salt consisting of a positively charged 2-bromo-N,N,N-trimethylethylamine cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a halogenating agent, for example in the bromination of olefins.

HY-Y0407A

Tetrapropylammonium hydroxide (40% w/w in water) TPAOH (40% w/w in water)	Biochemical Assay Reagents	Others
Tetrapropylammonium hydroxide (40% w/w in water)It is a compound belonging to the class of quaternary ammonium compounds and is a strong base with cationic properties. Tetrapropylammonium hydroxide (40% w/w in water)It is usually used as a phase transfer catalyst to promote the transfer of reactants between immiscible phases in various organic synthesis reactions. It is also used in the production of semiconductors, especially the manufacture of thin-film transistors and other electronic devices.

HY-N1428S4

Citric acid-18O	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Antibiotic	Cancer
Citric acid- ¹⁸O is ¹⁸O-labeled Citric acid (HY-N1428) Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice.

HY-16997A

Itacitinib adipate 5+ Cited Publications	JAK	Cancer
Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor which has been tested for efficacy and safety in a phase II trial in myelofibrosis.

HY-135453

(-)-Pinocembrin	Bacterial	Infection
(-)-Pinocembrin exhibits anti-mycobacterium activity against mycobacteriuum tuberculosis H37Ra with an IC₅₀ value of 1.11 mg/mL in dormant phase and 1.21 mg/mL in active phase, respectively. (-)-Pinocembrin has potent antiproliferative activity with IC₅₀ values of 1.88-11.00 mg/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines .

HY-W013231

N-Benzyl-N,N-diethylethanaminium iodide Benzyltriethylammonium iodide	Biochemical Assay Reagents	Others
N-Benzyl-N,N-diethylethanaminium iodide is a quaternary ammonium salt consisting of a positively charged N-benzyl-N,N-diethylethylamine cation and a negatively charged iodide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a reagent for the synthesis of various organic compounds, and as a surfactant or emulsifier in industrial and personal care products.

HY-W101256

N,N-Diethyl-N-methylethanaminium tetrafluoroborate Triethylmethylammonium tetrafluoroborate	Biochemical Assay Reagents	Others
N,N-Diethyl-N-methylethanaminium tetrafluoroborate is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is commonly used as a phase transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. Additionally, it is used as an electrolyte in electrochemical devices and as a surfactant in detergent formulations. Its unique chemical properties make it an important ingredient in a variety of industrial applications, including pharmaceuticals, agrochemicals, and materials science.

HY-N1428S6

Citric acid-d4-1	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Antibiotic	Cancer
Citric acid-d₄-1 is deuterated labeled Citric acid (HY-N1428) Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice.

HY-122099

Riddelline	DNA/RNA Synthesis	Others
Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver .

HY-N1428S3

Citric acid-13C3	Apoptosis Endogenous Metabolite Antibiotic
Citric acid- ¹³C₃ is the ¹³C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].

Cat. No.	Product Name

HY-L035

Drug Repurposing Compound Library

4,844 compounds

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved and clinical drugs, especially after phase I drugs, have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.

MCE Drug Repurposing Compound Library contains 4,844 approved drugs and passed phase Ⅰclinical drugs, which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties.

HY-L035P

Drug Repurposing Compound Library Plus

5,643 compounds

MCE Drug Repurposing Compound Library plus contains 5,643 approved and passed phase I clinical drugs, which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties.

MCE Drug Repurposing Compound Library plus, with more powerful screening capability, further complement MCE Drug Repurposing Compound Library (HY-L035) by adding some compounds with low solubility or stability (Part B) to this library. All those supplementary compounds are supplied in powder form.

HY-L112

Chemotherapy Drug Library

99 compounds

Chemotherapy is one of the most common treatments for cancer. It can be used alone for some types of cancer or in combination with other treatments such as radiation or surgery. Chemotherapy drugs usually target cells at different phases of the cell cycle and inhibit tumor proliferation and avoid cancer cell invasion and metastasis. It is a cancer treatment method that kills cancer cells with drugs.

Chemotherapeutic agents can be classified into alkylating agents, antimetabolites, antimicrotubular agents, antibiotics, etc. according to the mechanism of action. MCE offers a unique collection of 99 chemotherapy drugs, which is a useful tool for cancer treatment research.

HY-L004

Cell Cycle/DNA Damage Compound Library

2,037 compounds

DNA is prone to numerous forms of damage that can injure cells and impair fitness. Cells have developed an array of mechanisms to repair these injuries. Proliferating cells are especially vulnerable to DNA damage due to the added demands of cellular growth and division. Cell cycle checkpoints represent integral components of DNA repair that coordinate cooperation between the machinery of the cell cycle and several biochemical pathways that respond to damage and restore DNA structure. By delaying progression through the cell cycle, checkpoints provide more time for repair before the critical phases of DNA replication, when the genome is replicated, and of mitosis, when the genome is segregated. Loss or attenuation of checkpoint function may increase spontaneous and induced gene mutations and chromosomal aberrations by reducing the efficiency of DNA repair.

MCE owns a unique collection of 2,037 cell cycle/DNA damage-related compounds which can be used in the research of the same.

HY-L076

Drug-Induced Liver Injury (DILI) Compound Library

1,392 compounds

Drug-induced liver injury (DILI; also known as drug-induced hepatotoxicity) is caused by medications (prescription or OTC), herbal and dietary supplements (HDS), or other xenobiotics that result in abnormalities in liver tests or in hepatic dysfunction that cannot be explained by other causes. Drugs are an important cause of liver injury. Drug-induced hepatic injury is the most common reason cited for withdrawal of an approved drug.

DILI is thought to occur via several different mechanisms. Among these are direct impairment of the structural (e.g., mitochondrial dysfunction) and functional integrity of the liver; production of a metabolite that alters hepatocellular structure and function; production of a reactive drug metabolite that binds to hepatic proteins to produce new antigenic drug-protein adducts, which are targeted by hosts’ defenses (the hapten hypothesis); and initiation of a systemic hypersensitivity response (i.e., drug allergy) that damages the liver.

MCE Drug-induced Liver Injury (DILI) Compound Library contains a unique collection of 1,392 hepatotoxicity causing compounds and is a powerful tool to research DILI and other drug toxicities. This library can be used to understand the mechanisms of DILI, identify biomarkers for early DILI prediction, and allow timely recognition during drug development, thus finally achieving successful DILI prevention and assessment in the pre-marketing phase.

Cat. No.	Product Name	Type

HY-D0080

Laurdan 2 Publications Verification	Fluorescent Dyes/Probes
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase.

HY-D2190

Ag2S Oil phase (1200 nm)

Fluorescent Dyes/Probes

Ag2S Oil phase (1200 nm) is a fluorescent dyes.
HY-D2196

AgAuSe Oil phase (1120 nm)

Fluorescent Dyes/Probes

AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window.
HY-D2193

AgAuSe Oil phase (1000 nm)

Fluorescent Dyes/Probes

AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .

HY-151756

diSulfo-Cy3 alkyne	Fluorescent Dyes/Probes
diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an alkyne group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase .

HY-129811

Bis-ANS dipotassium	Fluorescent Dyes/Probes
Bis-ANS dipotassium is a fluorescent probe of hydrophobic protein. Bis-ANS binds to tubulin with a K_d of 2 μM . Bis-ANS dipotassium is a potent biphasic modulator of protein liquid-liquid phase separation (LLPS). Bis-ANS dipotassium promotes LLPS at low concentrations but suppresses LLPS at high concentrations .

HY-160198G

Vaccine adjuvant-1 (GMP)	Fluorescent Dye
Vaccine adjuvant-1 GMP is Vaccine adjuvant-1 produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Vaccine adjuvant-1 is an vaccine adjuvant is a vaccine adjuvant containing an oil phase, emulsifying agent and water .

HY-W127705

Quinacrine mustard dihydrochloride	Fluorescent Dyes/Probes
Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes .

HY-D2264

Caffeine orange

Fluorescent Dyes/Probes

Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices 。

HY-D0948

Celestine Blue

Dyes

Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO₂ nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .

Cat. No.	Product Name	Type

HY-W011052

Tetrapentylammonium bromide

Biochemical Assay Reagents

Tetrapentylammonium bromide is a quaternary ammonium salt consisting of a positively charged tetrapentylammonium cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic synthesis reactions to facilitate the transfer of reactants between immiscible phases. It is also used in the production of surfactants, detergents and the synthesis of pharmaceuticals.

HY-N1428A

Citric acid monohydrate 2 Publications Verification	Biochemical Assay Reagents
Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate causes renal toxicity in mice .

HY-Y1045

Tetrabutylammonium hydrogensulfate

TBAHS-MB

Biochemical Assay Reagents

Tetrabutylammonium hydrosulfate is a quaternary ammonium salt that is commonly used as a phase transfer catalyst, acid catalyst and reagent in various chemical reactions, especially in organic synthesis. Tetrabutylammonium hydrosulfate has unique chemical properties that allow it to facilitate the transfer of ions or molecules from one phase to another, making it an important ingredient in a variety of industrial processes.

HY-B2201

Citric acid trisodium 3 Publications Verification Sodium citrate; Trisodium citrate anhydrous	Biochemical Assay Reagents
Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice .

HY-Y0080

Methyl trioctyl ammonium chloride

Biochemical Assay Reagents

Methyl trioctyl ammonium chloride is a quaternary ammonium salt commonly used as a surfactant, stabilizer and phase transfer catalyst in various chemical reactions, especially in organic synthesis. Methyl trioctyl ammonium chloride has unique chemical properties that facilitate the transfer of ions or molecules from one phase to another, making it an important ingredient in a variety of industrial processes.

HY-W014408

Tetraethylammonium bromide

TEA bromide

Biochemical Assay Reagents

Tetraethylammonium bromide is a quaternary ammonium salt consisting of a positively charged tetraethylammonium cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a reagent for the synthesis of various organic compounds, an electrolyte in electrochemical experiments, and a source of tetraethylammonium ions in biochemical and pharmacological research.

HY-W100404

Tetramethylammonium 4-methylbenzenesulfonate

Biochemical Assay Reagents

Tetramethylammonium p-toluenesulfonate is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is widely used as a phase transfer catalyst in organic synthesis to facilitate the transfer of reactants between immiscible phases. Furthermore, it can be used as a surfactant, emulsifier or stabilizer in various industrial applications. Its unique chemical properties make it an important ingredient in the production of pharmaceuticals, agrochemicals and materials science products.

HY-W105516

N-Benzyl-N,N-dimethylbenzenaminium chloride

Phenylbenzyldimethylammonium chloride

Biochemical Assay Reagents

N-Benzyl-N,N-dimethylbenzeneminium chloride is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is widely used as a phase transfer catalyst in organic synthesis to facilitate the transfer of reactants between immiscible phases. In addition, it is used as an emulsifier, surfactant or disinfectant in various industrial applications. Its unique chemical properties make it an important ingredient in the production of pharmaceuticals, agrochemicals and polymer materials.

HY-W017224

Sodium butane-1-sulfonate Sodium 1-butanesulfonate	Biochemical Assay Reagents
Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) can be used as a mobile phase to separate arsenic or selenium compounds .

HY-W011972

Bromocholine bromide

Biochemical Assay Reagents

2-Bromo-N,N,N-trimethylethanaminium bromide is a quaternary ammonium salt consisting of a positively charged 2-bromo-N,N,N-trimethylethylamine cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a halogenating agent, for example in the bromination of olefins.

HY-Y0407A

Tetrapropylammonium hydroxide (40% w/w in water)

TPAOH (40% w/w in water)

Biochemical Assay Reagents

Tetrapropylammonium hydroxide (40% w/w in water)It is a compound belonging to the class of quaternary ammonium compounds and is a strong base with cationic properties. Tetrapropylammonium hydroxide (40% w/w in water)It is usually used as a phase transfer catalyst to promote the transfer of reactants between immiscible phases in various organic synthesis reactions. It is also used in the production of semiconductors, especially the manufacture of thin-film transistors and other electronic devices.

HY-W013231

N-Benzyl-N,N-diethylethanaminium iodide

Benzyltriethylammonium iodide

Biochemical Assay Reagents

N-Benzyl-N,N-diethylethanaminium iodide is a quaternary ammonium salt consisting of a positively charged N-benzyl-N,N-diethylethylamine cation and a negatively charged iodide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a reagent for the synthesis of various organic compounds, and as a surfactant or emulsifier in industrial and personal care products.

HY-W101256

N,N-Diethyl-N-methylethanaminium tetrafluoroborate

Triethylmethylammonium tetrafluoroborate

Biochemical Assay Reagents

N,N-Diethyl-N-methylethanaminium tetrafluoroborate is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is commonly used as a phase transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. Additionally, it is used as an electrolyte in electrochemical devices and as a surfactant in detergent formulations. Its unique chemical properties make it an important ingredient in a variety of industrial applications, including pharmaceuticals, agrochemicals, and materials science.

HY-W018574

Tetraoctylammonium bromide

Biochemical Assay Reagents

Tetraoctylammonium bromide (TOAB) is a quaternary ammonium salt consisting of a positively charged tetraoctylammonium cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It is also used as a surfactant and dispersant in various industrial applications, for example in the production of coatings, adhesives and polymers. Additionally, Tetraoctylammonium bromide has been investigated for potential applications in energy storage devices and as an antimicrobial agent.

HY-W099790

N-butyl-N-methyl-piperidinium bromide

1-Butyl-1-methylpiperidinium Bromide

Biochemical Assay Reagents

N-butyl-N-methyl-piperidinium bromide is a quaternary ammonium compound belonging to the class of piperidinium salts. N-butyl-N-methyl-piperidinium bromide is commonly used as a phase transfer catalyst in organic synthesis to transfer reactants between immiscible phases. It can also be used as a surfactant, corrosion inhibitor and antibacterial agent. Its unique chemical properties make it an important reagent in many different industries, including pharmaceuticals, agrochemicals, and materials science.

HY-W099930

N,N,N-Trimethylpropan-1-aminium bromide

Trimethylpropylammonium bromide

Biochemical Assay Reagents

N,N,N-Trimethylpropan-1-aminium bromide is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is widely used as a phase transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. It can also be used as a surfactant, corrosion inhibitor or antimicrobial. Due to its unique chemical properties, N,N,N-Trimethylpropan-1-aminium bromide has applications in various industries such as pharmaceuticals, agrochemicals, and materials science.

HY-W099682

Hexyltrimethylammonium bromide n-Hexyl trimethylammonium bromide	Biochemical Assay Reagents
Hexyltrimethylammonium bromide is a cationic surfactant, quaternary ammonium compound, detergent, emulsifier, phase transfer catalyst, antibacterial agent, electrochemical device, corrosion inhibitor, micelle former, industrial chemical.

HY-W099929

N-Ethyl-N,N-dipropylpropan-1-aminium iodide

Biochemical Assay Reagents

N-Ethyl-N,N-dipropylpropan-1-aminium iodide is a quaternary ammonium compound belonging to the class of alkylammonium salts. N-Ethyl-N,N-dipropylpropan-1-aminium (iodide) is commonly used as a phase transfer catalyst in organic synthesis to transfer reactants between immiscible phases. It can also be used as a surfactant, antimicrobial or corrosion inhibitor. Its unique chemical properties make it an essential reagent in many different industrial applications, including pharmaceuticals, agrochemicals, and materials science.

HY-W010795

Tetraheptylammonium bromide (>98%,BC)

Biochemical Assay Reagents

Tetraheptylammonium bromide (>98%,BC) (THAB) is a quaternary ammonium compound commonly used as a phase transfer catalyst in organic synthesis reactions, especially those involving charged species or polar reagents. It can facilitate the transfer of reactants between two immiscible phases, such as water and organic solvents, by forming stable ion pairs. In addition, THAB is used as a surfactant, and as an additive in various products such as cosmetics, pharmaceuticals, and detergents. Due to THAB's ability to form complexes with these ions, its potential use in the removal of heavy metal ions from wastewater was also investigated.

HY-W002327

Fmoc-Asn(Trt)-OH	Biochemical Assay Reagents
Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis .

HY-126437H

Poly-L-lysine hydrobromide (MW 4000-15000)	Cell Assay Reagents
Poly-L-lysine (hydrobromide) (MW 4000-15000) can promote cell adhesion to solid-phase substrates. Poly-L-lysine (hydrobromide) (MW 4000-15000) is a kind of biological materials or organic compounds that are widely used in life science research .

HY-126437I

Poly-L-lysine hydrobromide (MW 1000-5000)	Cell Assay Reagents
Poly-L-lysine (hydrobromide) (MW 1000-5000) can promote cell adhesion to solid-phase substrates. Poly-L-lysine (hydrobromide) (MW 1000-5000) is a kind of biological materials or organic compounds that are widely used in life science research .

HY-126437E

Poly-L-lysine hydrobromide (MW 15000-30000)	Cell Assay Reagents
Poly-L-lysine (hydrobromide) (MW 15000-30000) can promote cell adhesion to solid-phase substrates. Poly-L-lysine (hydrobromide) (MW 15000-30000) is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W127423

Methyl 2-hydroxyoctadecanoate	Biochemical Assay Reagents
Methyl (+/-)-2-hydroxystearateis a hydroxylated fatty acid methyl ester that broadens phase transitions in dimyristoylphosphatidylcholine (DMPC) lipid membranes. It has been used in the synthesis of lipid-nucleotide conjugated anti-HIV agents to increase the cleavage of phosphodiester bonds and the number of released intracellular nucleotides.

HY-W010361

Tetramethylammonium acetate

Biochemical Assay Reagents

Tetramethylammonium acetate is an organic compound commonly used as a phase transfer catalyst in organic synthesis reactions, especially those involving charged species or polar reagents. It can facilitate the transfer of reactants between two immiscible phases, such as water and organic solvents, by forming stable ion pairs. Additionally, Tetramethylammonium acetate has been used to prepare a variety of organic compounds, including esters, amides, and carboxylic acids. Due to its unique physicochemical properties, it has also been investigated for its potential use in developing new materials such as ionic liquids and liquid crystals. "x" in the formula represents the number of water molecules in the crystal structure, which can vary depending on the preparation method.

HY-W127671

Tetramethylammonium perchlorate	Biochemical Assay Reagents
Tetramethylammonium perchlorate is used as an intermediate in organic and chemical synthesis. It is used as mobile phase in HPLC analysis and quantification of olanzapine, clozapine and N-desmethylclozapine. It acts as a supporting electrolyte in the electrochemical reduction of 1-bromodecane, 1-iodododecane, 2-iodooctane, and 2-bromooctane on a mercury cathode.

HY-W017054

2-Amino-2-methyl-1,3-propanediol	Biochemical Assay Reagents
2-Amino-2-methyl-1,3-propanediol is a solid-solid phase change materials (PCMs). Amino-2-methyl-1,3-propanediol can be used to make surfactants, vulcanization accelerators and as a biological buffer .

HY-160198G

Vaccine adjuvant-1 (GMP)	Biochemical Assay Reagents
Vaccine adjuvant-1 GMP is Vaccine adjuvant-1 produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Vaccine adjuvant-1 is an vaccine adjuvant is a vaccine adjuvant containing an oil phase, emulsifying agent and water .

HY-W040184

Tetramethylammonium hydrogensulfate

TMAHS

Biochemical Assay Reagents

Tetramethylammonium hydrogensulfate, sometimes abbreviated as TMAHS, is a quaternary ammonium salt commonly used as a catalyst and phase transfer agent in chemical reactions, especially in organic synthesis. In addition, it is used as an electrolyte additive in electrochemical and rechargeable batteries. TMAHSs have also been investigated for their potential use in various applications such as wastewater treatment, gas separation, and fuel cells.

HY-W099642

Trimethyloctylammonium bromide

Trimethyl-n-octylammonium bromide

Biochemical Assay Reagents

Trimethyloctylammonium bromide (TOAB) is used as a surfactant and phase transfer catalyst in various chemical reactions. TOAB can be used in the synthesis of nanomaterials due to its ability to selectively transfer ions across interfaces and as a surfactant in the production of emulsions and foams. It is valued for its amphiphilic properties, which allow it to interact with water and oils, stabilizing and dispersing mixtures.

HY-W073183

Dibenzo-24-crown-8-ether	Biochemical Assay Reagents
Dibenzo-24-crown-8-ether is a phase transfer catalyst that can reduce H ²PtCl ⁶·6H ²O and FeCl ²·4H ²O in a thermal system to synthesize 17 nm monodispersed iron-platinum (FePt) alloy nanoparticles .

HY-126437A

Poly-L-lysine hydrochloride

Drug Delivery

Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .

HY-P2969

Complement factor I	Biochemical Assay Reagents
Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) .

Cat. No.	Product Name	Target	Research Area

HY-Y1636

Fmoc-Arg(Pbf)-OH	Amino Acid Derivatives	Others
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .

HY-113638

CVT-11127 GS-456332	Stearoyl-CoA Desaturase (SCD) Apoptosis	Cancer
CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer .

HY-P1032S1

Angiotensin I-13C5,15N (human, mouse, rat)	Isotope-Labeled Compounds Endogenous Metabolite	Others
Angiotensin I- ¹³C₅, ¹⁵N (human, mouse, rat) is the ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

HY-16375

Ozarelix D-63153	GnRH Receptor Apoptosis	Cancer
Ozarelix (D-63153) is a GnRH antagonist. Ozarelix induces cell apoptosis and arrests cell in G2/M phase. Ozarelix can be used in the research of prostate cancer .

HY-P2219

CGGRGD	Peptides	Cancer
CGGRGD, a RGD derivative with cysteine as its N-terminal, CGGRGD is synthesized via solid-phase peptide synthesis technique and the surface of PCL fibers is aminolysised by amino 2-cyanobenzothiazole followed by the addition of 2-cyanobenzothiazole (CBT) .

HY-P2219A

CGGRGD TFA	Peptides	Cancer
CGGRGD TFA, a RGD derivative with cysteine as its N-terminal, CGGRGD TFA is synthesized via solid-phase peptide synthesis technique and the surface of PCL fibers is aminolysised by amino 2-cyanobenzothiazole followed by the addition of 2-cyanobenzothiazole (CBT) .

HY-P10324

TAT-p16 p16^INK4a peptide	Peptides	Cancer
TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .

HY-P5997

XQ2B	Peptides	Inflammation/Immunology
XQ2B is a cGAS inhibitor targeting protein-DNA interactions and phase separation. XQ2B inhibits herpes simplex virus 1 (HSV-1)-induced antiviral immune responses and enhances HSV-1 infection in vitro and in vivo .

HY-P3630

Stick Insect Hypertrehalosaemic Factor II	Peptides	Others
Stick Insect Hypertrehalosaemic Factor II is a synthetic peptide. Stick Insect Hypertrehalosaemic Factor II has the same FAB spectra, reversed-phase high-performance liquid chromatographic behavior, and biological behavior as the natural material. Stick Insect Hypertrehalosaemic Factor II can be used for the research of hypertrehalosaemic effect .

HY-W010712

Fmoc-His(Trt)-OH	Amino Acid Derivatives	Others
Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH₂. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation .

HY-P2969

Complement factor I	Endogenous Metabolite	Metabolic Disease
Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) .

HY-P10376

Lucicebtide	Peptides	Cancer
Lucicebtide (Compound ST101) is a selective antagonist for CCAAT/enhancer binding protein β (C/EBPβ). Lucicebtide binds to the leucine zipper domain of C/EBPβ, prevents its dimerization, and ubiquitin-dependently degrades C/EBPβ. Lucicebtide arrests cell cycle at G0/G1 phase. Lucicebtide exhibits cytotoxicity in cancer cells. Lucicebtide exhibits good pharmacokinetic characters and inhibits tumor growth in mouse model .

HY-P6020

HBpep-SA	Peptides	Others
HBpep-SA is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines .

HY-P6020A

HBpep-SA TFA	Peptides	Others
HBpep-SA is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-77817

Pyrrole-2-carboxaldehyde	Alkaloids other families Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
Pyrrole-2-carboxaldehyde has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase .

HY-N8487

7-Methoxyflavone	Flavonoids Classification of Application Fields Neurological Disease Flavones Leguminosae Zornia brasiliensis Source classification Plants Disease Research Fields Inflammation/Immunology	Others
7-Methoxyflavone is a compound isolated from Zornia brasiliensis. 7-Methoxyflavone has peripheral antinociceptive activity. 7-Methoxyflavone inhibits paw-licking time in the neurogenic phase of the formalin pain response (65.6%) and did not decrease the nociceptive response in the inflammatory phase .

HY-N1428A

Citric acid monohydrate 2 Publications Verification	Preservatives Classification of Application Fields Source classification Rosaceae Metabolic Disease Plants Endogenous metabolite Food Research Microorganisms Ketones, Aldehydes, Acids Malus pumila Mill. Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Apoptosis Antibiotic
Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate causes renal toxicity in mice .

HY-N0421

Cinobufagin 3 Publications Verification Cinobufagine	Structural Classification Classification of Application Fields Animals Source classification Disease Research Fields Steroids Cancer	Apoptosis
Cinobufagin is an anticancer agent that can be secreted by the Asiatic toad Bufo gargarizans. Cinobufagin induces the cell cycle arrests in the G1 phase or G2/M phase, leading to apoptosis in cancer cells. Cinobufagin inhibits tumor growth in melanoma and glioblastoma multiforme xenograft mouse models .

HY-N1428

Citric acid 3 Publications Verification	Cardiovascular Disease Structural Classification Preservatives Classification of Application Fields Anti-aging Source classification Endocrine diseases Metabolic Disease Endogenous metabolite Food Research Infection Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Inflammation/Immunology Disease Research Fields Cancer	Apoptosis Endogenous Metabolite Antibiotic
Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

HY-B2201

Citric acid trisodium 3 Publications Verification Sodium citrate; Trisodium citrate anhydrous	Structural Classification Preservatives Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Food Research	Apoptosis Endogenous Metabolite
Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice .

HY-Y0801

2,6-Dihydroxybenzoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2,6-Dihydroxybenzoic acid is a secondary metabolite of salicylic acid which has been hydrolyzed by liver enzymes during phase I metabolism.

HY-135453

(-)-Pinocembrin	Structural Classification Flavonoids Flavones Polygonaceae Source classification Persicaria glabra (Willd.) M. Gomez Plants	Bacterial
(-)-Pinocembrin exhibits anti-mycobacterium activity against mycobacteriuum tuberculosis H37Ra with an IC₅₀ value of 1.11 mg/mL in dormant phase and 1.21 mg/mL in active phase, respectively. (-)-Pinocembrin has potent antiproliferative activity with IC₅₀ values of 1.88-11.00 mg/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines .

HY-122099

Riddelline	Alkaloids Erythrina lysistemon Hutch. Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Plants Compositae Disease Research Fields	DNA/RNA Synthesis
Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver .

HY-N8287

Oxaline	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Microtubule/Tubulin
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase .

HY-N10394

Metachromins X	Quinones Structural Classification Classification of Application Fields Animals Terpenoids Sesquiterpenes Marine natural products Benzene Quinones Sponge Disease Research Fields Cancer	Others
Metachromins X is a sesquiterpene quinone that arrests the cell cycle progression of HeLa/Fucci2 cells at S/G2/M phase .

HY-W041895

DL-Glutamic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability .

HY-152245

Physachenolide C	Structural Classification Source classification Physalis chenopodifolia Lam Plants Solanaceae Steroids	Epigenetic Reader Domain
Physachenolide C is a potent and selective BET inhibitor that induces apoptosis and arrests the cell cycle in the G0-G1 phase, with antitumor activity .

HY-N10670

Bursehernin Methylpluviatolide	Structural Classification Hernandia sonora Linn. other families Source classification Lignans Phenylpropanoids Plants	Apoptosis
Bursehernin (Methylpluviatolide) is an antitumor agent. Bursehernin induces Apoptosis and cell cycle arrest at G2/M phase. Bursehernin shows anti-proliferative activity .

HY-N1039A

Manool	Natural Products Classification of Application Fields Labiatae Source classification Plants Pteris semipinnata L. Sp. Disease Research Fields Cancer Vachellia nilotica (L.) P. J. H. Hurter & Mabb.	Others
Manool is a diterpene from Salvia officinalis. Manool induces selective cytotoxicity in cancer cells. Manool arrests the cancer cells at the G(2)/M phase of the cell cycle .

HY-N10798

Kusunokinin (-)-Kusunokinin	Structural Classification Source classification Lignans Piperaceae Phenylpropanoids Plants Piper nigrum Linn.	Apoptosis
Kusunokinin ((-)-Kusunokinin) is a nature product that could be isolated form P. nigrum. Kusunokinin has anticancer activity. Kusunokinin arrests cell cycle at G2/M phase and induce apoptosis .

HY-N4171

Dihydrocucurbitacin B	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	Apoptosis
Dihydrocucurbitacin B, a triterpene isolated from Cayaponia tayuya roots, inhibits nuclear factor of activated T cells (NFAT), induces cell cycle arrested in the G0 phase, and inhibits delayed type hypersensitivity .

HY-N6868

Dimethyl lithospermate B dmLSB	Cardiovascular Disease Classification of Application Fields Labiatae Source classification Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields	Sodium Channel
Dimethyl lithospermate B (dmLSB) is a selective Na ⁺ channel agonist. Dimethyl lithospermate B slows inactivation of sodium current (INa), leading to increased inward current during the early phases of the action potential (AP) .

HY-122496

Malvidin chloride Syringidin	Structural Classification Classification of Application Fields Source classification Vitis vinifera cv. Zalema Plants Vitaceae Anthocyans Flavonoids other families Microorganisms Phenols Polyphenols Disease Research Fields Cancer	Apoptosis
Malvidin (chloride) is a bioactive compound isolated from grape. Malvidin shows cytotoxicity through the arrest of the G₂/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer .

HY-N7335

Dehydroglyasperin C	Flavonoids Classification of Application Fields Neurological Disease Leguminosae Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Glycyrrhiza uralensis Fisch. Isoflavones	Others
Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities .

HY-126423

Isorhamnetin 3-glucuronide Isorhamnetin 3-O-glucuronide	Structural Classification Flavonoids Flavones Source classification Endogenous metabolite	Others
Isorhamnetin 3-glucuronide is a potent anticancer agent. Isorhamnetin 3-glucuronide shows anti-proliferative activity. Isorhamnetin 3-glucuronide induces Apoptosis and cell cycle arrest at S-phase .

HY-13605

Cytarabine 35+ Cited Publications Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Marine natural products Sponge Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog HSV Autophagy Apoptosis Endogenous Metabolite Orthopoxvirus
Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC₅₀ of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity.

HY-N6688

Verruculogen	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Potassium Channel Bacterial Antibiotic
Verruculogen is a toxin produced mainly by Penicillium and Aspergillus spp. and causes severe tremors in affected animals. Verruculogen inhibits Ca ²⁺-activated K ⁺ channels. Verruculogen is an M phase inhibitor of the mammalian cell cycle .

HY-N11645

Ganoderic acid Mf GA-Mf	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Apoptosis
Ganoderic acid Mf is an antitumor triterpenoid. Ganoderic acid Mf causes cell cycle arrest in the G1 phase. Ganoderic acid Mf shows high selectivity between normal and cancer cells and induces cell apoptosis via mitochondria mediated pathway .

HY-N6722

Swainsonine Tridolgosir	Infection Alkaloids Piperidine Alkaloids Structural Classification Pyrrole Alkaloids Classification of Application Fields Leguminosae Source classification Plants Disease Research Fields Sphaerophysa salsula	Apoptosis Antibiotic
Swainsonine (Tridolgosir) is an natural indolizidine alkaloid, a potent and reversible α-mannosidase inhibitor. Swainsonine induces apoptosis and cell cycle arrest at G2/M phase. Swainsonine shows anti-tumor activity .

HY-N7045

Isosilybin B 1 Publications Verification	Flavanonols Flavonoids Glycine soya Classification of Application Fields Source classification Phenols Polyphenols Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Disease Research Fields Cancer	Androgen Receptor Apoptosis
Isosilybin B, a flavonolignan isolated from Silybum marianum, has anti-prostate cancer (PCA) activity via inhibiting proliferation and inducing G1 phase arrest and apoptosis. Isosilybin B causes androgen receptor (AR) degradation .

HY-N10344

Glucoarabin	Structural Classification Natural Products Classification of Application Fields Source classification Camelina sativa (L.) Crantz Glucosinolates Plants Brassicaceae Disease Research Fields Cancer	Others
Glucoarabin is a bioactive glucosinolate. In Hepa1c1c7 cells, hydrolyzed Glucoarabin (hGSL 9) upregulates the phase II detoxification enzyme quinone reductase (NQO1), with no effect on cytochrome P450 (CYP) 1A1 activity .

HY-N6725

Sterigmatocystine	Infection Structural Classification Monophenols Microorganisms Xanthones Classification of Application Fields Source classification Phenols Disease Research Fields	DNA/RNA Synthesis Bacterial Apoptosis Antibiotic Endogenous Metabolite
Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor . Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals .

HY-N2374

Eupatorin	Structural Classification Flavonoids Classification of Application Fields Flavones Cruciferae Source classification Phenols Polyphenols Isatis tinctoria L. Plants Disease Research Fields Cancer	Apoptosis
Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly(ADP-ribose) polymerase cleavage .

HY-13680

Meisoindigo Dian III; N-Methylisoindigotin; Natura-α	Alkaloids Structural Classification other families Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids Cancer	Apoptosis
Meisoindigo (Dian III), a derivative of Indirubin (HY-N0117), halts the cell cycle at the G0/G1 phase and induces apoptosis in primary acute myeloid leukemia (AML) cells. Meisoindigo exhibits high antitumor activity .

HY-N1196

Suberosin	Structural Classification Classification of Application Fields Source classification Coumarins Phenylpropanoids Umbelliferae Plants Pluchea indica (L.) Less. Inflammation/Immunology Disease Research Fields	NF-κB
Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation of the transcription factors NF-AT and NF-κB .

HY-125098

Illudin S	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	DNA Alkylator/Crosslinker Apoptosis
Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells .

HY-B1508

Vitamin K4 Acetomenaphthone	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .

HY-N9507

Picrasidine Q	Alkaloids other families Classification of Application Fields Source classification Quinoline Alkaloids Plants Disease Research Fields Indole Alkaloids Cancer	Apoptosis FGFR
Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase activity .

HY-N9968

Cucurbitacin C	Triterpenes Structural Classification Terpenoids Source classification Cucurbitaceae Plants Cucumis sativus L.	Akt Apoptosis
Cucurbitacin C is a triterpenoid calabinoid that can be isolated from Cucurbitaceae plants. Cucurbitacin C has anti-cancer activity in vivo and in vitro. Cucurbitacin C can induce cell cycle arrest in G1 or G2/M phase and apoptosis by inhibiting Akt signaling .

HY-N7043

Isosilybin A 1 Publications Verification	Flavanonols Flavonoids Glycine soya Classification of Application Fields Source classification Phenols Polyphenols Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Disease Research Fields Cancer	Apoptosis
Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis .

HY-N0636

Eriocitrin 1 Publications Verification	Structural Classification Flavonoids Classification of Application Fields Citrus limon (L.) Burm. F. Flavonones Source classification Rutaceae Phenols Polyphenols Plants Disease Research Fields Cancer	Apoptosis
Eriocitrin is a flavonoid isolated from lemons that is a powerful antioxidant. Eriocitrin inhibits the proliferation of liver cancer cells by arresting the cell cycle in the S phase by upregulating p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating intrinsic signaling pathways involving mitochondria .

HY-13605R

Cytarabine (Standard)	Structural Classification Natural Products Microorganisms Marine natural products Source classification Sponge Endogenous metabolite	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog HSV Autophagy Apoptosis Endogenous Metabolite Orthopoxvirus
Cytarabine (Standard) is the analytical standard of Cytarabine. This product is intended for research and analytical applications. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC₅₀ of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity.

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Disease Research Fields Selaginella tamariscina (P. Beauv.) Spring Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N6663

3-Carene	Other Monoterpenes other families Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	COX
3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation .

HY-N3446

IVHD-valtrate	Natural Products Classification of Application Fields Source classification Valeriana officinalis Linn. Plants Valerianaceae Disease Research Fields Cancer	Apoptosis
IVHD-valtrate, an active Valeriana jatamansi derivative, is against human ovarian cancer cells in vitro and in vivo. IVHD-valtrate induces cancer cells apoptosis and arrests the ovarian cancer cells in the G2/M phase. IVHD-valtrate has the potential to be a novel chemotherapeutic agent for the human ovarian cancer research .

HY-133537

Hygrolidin	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields	Antibiotic Fungal ADC Cytotoxin
Hygrolidin is a 16-membered macrolide antibiotic produced by Streptomyces hygroscopicus D-1166. Hygrolidin has anti-fungus activity against Valsa ceratosperma. Hygrolidin induces p21 expression and abrogates cell cycle progression at G1 and S phases. Hygrolidin has antitumor activity .

HY-126566

Trichostatin C	Structural Classification Natural Products Microorganisms Source classification	Fungal HDAC Apoptosis
Trichostatin C is an inhibitor for histone deacetylase (HDAC), induces apoptosis and arrests cell cycle at G2/M phase, and exhibits anticancer activity against lung cancer and urothelial bladder cancer . Trichostatin C induces differentation of Friend leukemic cells . Trichostatin C exhibits antifungal activity .

HY-N0047

Polyphyllin I 1 Publications Verification	Structural Classification Liliaceae Classification of Application Fields Paris polyphylla Smith Plants Disease Research Fields Saccharides Steroids Cancer	JNK mTOR Akt PDK-1 Autophagy Apoptosis
Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis .

HY-N2374R

Eupatorin (Standard)	Structural Classification Flavonoids Classification of Application Fields Cruciferae Source classification Phenols Isatis tinctoria L. Plants Disease Research Fields Cancer	Apoptosis
Eupatorin (Standard) is the analytical standard of Eupatorin. This product is intended for research and analytical applications. Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly(ADP-ribose) polymerase cleavage .

HY-N6725R

Sterigmatocystine (Standard)	Infection Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Disease Research Fields	DNA/RNA Synthesis Bacterial Apoptosis Antibiotic Endogenous Metabolite
Sterigmatocystine (Standard) is the analytical standard of Sterigmatocystine. This product is intended for research and analytical applications. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor . Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals .

HY-B1357

Digitoxin 3 Publications Verification	Cardiovascular Disease Digitalis purpurea Linn. Structural Classification Microorganisms Classification of Application Fields Source classification Scrophulariaceae Plants Disease Research Fields Steroids	Bcl-2 Family Caspase Apoptosis HSV Na+/K+ ATPase Calcium Channel
Digitoxin is an anti-cancer agent. Digitoxin induces apoptosis, inhibits influenza cytokine storm, causes DNA double-stranded breaks (DSBs) and blocks the cell cycle at the G2/M phase. Digitoxin induces calcium uptake into cells by forming transmembrane calcium channels and can be used for research of heart failure .

HY-N10268

3-Hydroxyterphenyllin NSC 299113	Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields Cancer	Apoptosis
3-Hydroxyterphenyllin is a metabolite of Aspergillus candidus.3-Hydroxyterphenyllin suppresses proliferation and causes cytotoxicity against A2780/CP70 and OVCAR-3 cells. 3-Hydroxyterphenyllin induces S phase arrest and apoptosis. 3-Hydroxyterphenyllin has the potential for the research of ovarian cancer .

HY-N10018

Cimiside E 25-Anhydrocimigenol xyloside	Triterpenes Structural Classification Terpenoids Source classification Ranunculaceae Plants Cimicifuga racemosa (L.) Nutt.	Caspase
Cimiside E (25-Anhydrocimigenol xyloside) is a triterpene xyloside, Cimiside E possesses apoptotic action on gastric cancer cells, with an IC₅₀ value of 14.58 μM. Cimiside E induces cell cycle arrest at G2/M phase, and mediates apoptosis through the induction of the caspase cascade for both the extrinsic and intrinsic pathways .

HY-125527

Resolvin D1 RvD1	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	Endogenous Metabolite
Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .

Cat. No.	Product Name	Chemical Structure

HY-N1428S6

Citric acid-d4-1
Citric acid-d₄-1 is deuterated labeled Citric acid (HY-N1428) Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice.

HY-111973S3

Phaseic acid-d4

Phaseic acid-d₄ is the deuterium labeled Phaseic acid[1].

HY-B0615AS

Moricizine-d8(Hydrochloride)
Moricizine-d₈ (Hydrochloride) is the deuterium labeled Moricizine Hydrochloride (HY-B0615A). Moricizine Hydrochloride is an orally active Class I antiarrhythmic agent. Moricizine Hydrochloride decreases the maximum rate of phase 0 depolarization; increases rates of phase 2 and 3 repolarization, decreases action potential duration, and decreases effective refractory period[1][2].

HY-N1428S4

Citric acid-18O
Citric acid- ¹⁸O is ¹⁸O-labeled Citric acid (HY-N1428) Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice.

HY-N1428S3

Citric acid-13C3
Citric acid- ¹³C₃ is the ¹³C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].

HY-N0273S

Brassinolide-d5

Brassinolide-d₅ (Brassin lactone-d₅) is the deuterated labeled Brassinolide (HY-N0273). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

HY-N6600S

Octadecane-d38

Octadecane-d₃₈ is the deuterium labeled Octadecane[1]. Octadecane is an alkane that is used to store thermal energy at ambient temperature as a phase change material[2].

HY-P1032S1

Angiotensin I-13C5,15N (human, mouse, rat)

Angiotensin I- ¹³C₅, ¹⁵N (human, mouse, rat) is the ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice .

HY-W041895S

DL-Glutamic acid-d5
DL-Glutamic acid-d₅ is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

HY-W041895S1

DL-Glutamic acid-d3
DL-Glutamic acid-d₃ is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

HY-P10324

TAT-p16

TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .

HY-13605S

Cytarabine-d2
Cytarabine-d₂ is the deuterium labeled Cytarabine. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV[1][2].

HY-N1952S

Isoeugenol-d3
Isoeugenol-d₃ is deuterated labeled Sterigmatocystine (HY-N6725). Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor . Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals .

HY-Y1636S1

L-Arginine-N-FMOC PBF-OH-13C6
L-Arginine-N-FMOC PBF-OH- ¹³C₆ is the ¹³C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].

HY-17401S

Ranolazine-d8 dihydrochloride

Ranolazine-d₈ (dihydrochloride) is the deuterium labeled Ranolazine dihydrochloride. Ranolazine dihydrochloride (CVT 303 dihydrochloride) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine dihydrochloride is also a partial fatty acid oxidation inhibitor[3].

HY-W016099S

3-Methyl-2-quinoxalinecarboxylic acid-d4
3-Methyl-2-quinoxalinecarboxylic acid-d₄ is the deuterium labeled 3-Methyl-2-quinoxalinecarboxylic acid. 3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1].

HY-B0280S2

Ranolazine-d3
Ranolazine-d₃ is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor[3]. Antianginal agent.

HY-B0280S1

Ranolazine-d8
Ranolazine-d₈ is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor[3]. Antianginal agent.

HY-B0280S

Ranolazine-d5
Ranolazine-d₅ is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor[3]. Antianginal agent.

HY-B1658S

Frovatriptan-d3 hydrochloride
Frovatriptan-d₃ (hydrochloride) is the deuterium labeled Frovatriptan[1]. Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura[2].

HY-W010712S1

Fmoc-His(Trt)-OH-15N3
Fmoc-His(Trt)-OH- ¹⁵N₃ is the ¹⁵N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].

HY-125527S

Resolvin D1-d5

Resolvin D1-d₅ is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages[1][2].

HY-114041S1

Resolvin E1-d4-1

Resolvin E1-d₄-1 is the deuterium labeled Resolvin E1. Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production[1][2].

Cat. No.	Product Name		Classification

HY-151825

Fmoc-L-Phe(4-NH-Poc)-OH		Alkynes
Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry .

HY-151756

diSulfo-Cy3 alkyne		Labeling and Fluorescence Imaging Alkynes
diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an alkyne group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase .

HY-155541

Antitumor agent-110		Alkynes
Antitumor agent-110 (compound 13) is an anticancer imidazotetrazine with good permeability properties. Antitumor agent-110 arrests cell cycel at G2/M phase, and induces apoptosis . Antitumor agent-110 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151637

Fmoc-N-propargyl-MPBA		Alkynes
Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures . Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147858

PROTAC EGFR degrader 7		Alkynes
PROTAC EGFR degrader 7 (compound 13b) is a potent and selective CRBN-recruiting PROTAC EGFR ^L858R/T790M degrader, with a DC₅₀ of 13.2 nM. PROTAC EGFR degrader 7 inhibits NCI–H1975 cells proliferation, with an IC₅₀ of 46.82 nM. PROTAC EGFR degrader 7 significantly induces apoptosis and G2/M phase arrest in NCI–H1975 cell. PROTAC EGFR degrader 7 shows antitumor activity, and can be used for non-small cell lung cancer (NSCLC) research . PROTAC EGFR degrader 7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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