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RFC-1

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2

Inhibitors & Agonists

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10446
    Pralatrexate
    4 Publications Verification

    Antifolate Apoptosis Cancer
    Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor with a Ki of 13.4 pM. Pralatrexate is a substrate for folylpolyglutamate synthetase with improved cellular uptake and retention. Pralatrexate has antitumor activities and has the potential for relapsed/refractory T-cell lymphoma treatment [1] . Pralatrexate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Pralatrexate
  • HY-RS11865

    Small Interfering RNA (siRNA) Others

    RFC1 Human Pre-designed siRNA Set A contains three designed siRNAs for RFC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RFC1 Human Pre-designed siRNA Set A
    RFC1 Human Pre-designed siRNA Set A

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