V1/S

By Targets:	Akt (1) E3 Ligase Ligand-Linker Conjugates (1) HIV (1) Isotope-Labeled Compounds (2) Parasite (4) PKC (1) Ras (3) STAT (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Infection (5)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128554S

N-Desethyl amodiaquine-d5	Isotope-Labeled Compounds Parasite	Infection
N-Desethyl amodiaquine-d₅ is the deuterium labeled N-Desethyl amodiaquine. N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

HY-128554S1

N-Desethyl amodiaquine-d5 dihydrochloride	Isotope-Labeled Compounds Parasite	Infection
N-Desethyl amodiaquine-d₅ (dihydrochloride) is the deuterium labeled N-Desethyl amodiaquine dihydrochloride. N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

HY-128554

N-Desethyl amodiaquine 1 Publications Verification	Parasite	Infection
N-Desethyl amodiaquine is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine is an antiparasitic agent, has inhibitory for strains V1/S and 3D7 with IC₅₀ values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine can be used for the research of malaria .

HY-128554A

N-Desethyl amodiaquine dihydrochloride 1 Publications Verification	Parasite	Infection
N-Desethyl amodiaquine dihydrochloride is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent, has inhibitory for strains V1/S and 3D7 with IC₅₀ values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine dihydrochloride can be used for the research of malaria .

HY-P5439

Epsilon-V1-2, Cys-conjugated	PKC	Others
Epsilon-V1-2, Cys-conjugated is a biological active peptide. (This peptide is the εPKC specific inhibitor. Its inhibitory activity is based on εPKC translocation and MARCKS phosphorylation. This peptide interferes with εPKC interaction with the anchoring protein εRACK. This peptide contains a cysteine residue added to the C-terminus for potential S-S bond formation with a carrier protein.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

HY-131959

(S,R,S)-AHPC-PEG5-Boc	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG5-Boc is a E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for Cdc20 degrader CP5V .

HY-144212

SOS1-IN-8

Ras Cancer

SOS1-IN-8 is a potent SOS1 inhibitor with IC₅₀s of 11.6 and 40.7 nM for SOS1-G12D and SOS1-G12V, respectively (WO2022017339A1, compound 2) .
HY-144211

SOS1-IN-7

Ras Cancer

SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with IC₅₀s of 20 and 67 nM for SOS1-G12D and SOS1-G12V, respectively .
HY-144210

SOS1-IN-6

Ras Cancer

SOS1-IN-6 (compound 33-P1) is a potent SOS1 inhibitor with IC₅₀s of 14.9 and 73.3 nM for SOS1-G12D and SOS1-G12V, respectively .

SOS1-IN-8	Ras	Cancer
SOS1-IN-8 is a potent SOS1 inhibitor with *IC₅₀s of 11.6 and 40.7 nM for SOS1-G12D and SOS1*-G12V, respectively (WO2022017339A1, compound 2) .

SOS1-IN-7	Ras	Cancer
SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with *IC₅₀s of 20 and 67 nM for SOS1-G12D and SOS1*-G12V, respectively .

SOS1-IN-6	Ras	Cancer
SOS1-IN-6 (compound 33-P1) is a potent SOS1 inhibitor with *IC₅₀s of 14.9 and 73.3 nM for SOS1-G12D and SOS1*-G12V, respectively .

HY-N0751

Scutellarin Maximum Cited Publications 9 Publications Verification	STAT Akt HIV	Infection Cancer
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, *HIV-1(74V)* and HIV-1KM018 with *EC₅₀*s of 26 μM, 253 μM and 136 μM, respectively.

Cat. No.	Product Name	Target	Research Area

HY-P5439

Epsilon-V1-2, Cys-conjugated	PKC	Others
Epsilon-V1-2, Cys-conjugated is a biological active peptide. (This peptide is the εPKC specific inhibitor. Its inhibitory activity is based on εPKC translocation and MARCKS phosphorylation. This peptide interferes with εPKC interaction with the anchoring protein εRACK. This peptide contains a cysteine residue added to the C-terminus for potential S-S bond formation with a carrier protein.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

HY-P1737

Conopressin S

Con-S
Peptides Cardiovascular Disease

Conopressin S, isolated from Conus striatus, shows high affinity with vasopressin V1b receptor (AVPR1B), with a K_i of 8.3 nM .

Conopressin S Con-S	Peptides	Cardiovascular Disease
Conopressin S, isolated from Conus striatus, shows high affinity with vasopressin V1b receptor (AVPR1B), with a K_i of 8.3 nM .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0751

Scutellarin 5+ Cited Publications	Infection Structural Classification Flavonoids Scutellaria baicalensis Georgi Classification of Application Fields Flavones Labiatae Source classification Phenols Polyphenols Plants Disease Research Fields	STAT Akt HIV
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, *HIV-1(74V)* and HIV-1KM018 with *EC₅₀*s of 26 μM, 253 μM and 136 μM, respectively.

Cat. No.	Compare	Product Name	Species	Source

HY-P76159

	ATP6V1F Protein, Human (GST) V-type proton ATPase subunit F; V-ATPase subunit F; V-ATPase 14 kDa subunit; ATP6S14; VATF	Human	E. coli
	ATP6V1F is an important subunit of the vacuolar (H+)-ATPase (V-ATPase) V1 complex and is an important component of this enzyme's role in cellular pH regulation. It forms a catalytic AB heterodimer and peripheral stem that plays a role in ATP hydrolysis. ATP6V1F Protein, Human (GST) is the recombinant human-derived ATP6V1F protein, expressed by E. coli , with N-GST labeled tag. The total length of ATP6V1F Protein, Human (GST) is 119 a.a., with molecular weight of ~40 KDa.


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-128554S

N-Desethyl amodiaquine-d5
N-Desethyl amodiaquine-d₅ is the deuterium labeled N-Desethyl amodiaquine. N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

HY-128554S1

N-Desethyl amodiaquine-d5 dihydrochloride
N-Desethyl amodiaquine-d₅ (dihydrochloride) is the deuterium labeled N-Desethyl amodiaquine dihydrochloride. N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Name
Email *

	Sorry, but the email address you supplied was invalid.

V1/S

Inhibitors & Agonists

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Natural
Products