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Results for "

Vonoprazan

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100007
    Vonoprazan
    3 Publications Verification

    TAK-438 free base

    		 Proton Pump Bacterial Endocrinology
    Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan inhibits H +,K +-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori .
    <em>Vonoprazan</em>
  • HY-15295
    Vonoprazan Fumarate
    3 Publications Verification

    TAK-438

    		 Proton Pump Metabolic Disease
    Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H +,K +-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease .
    <em>Vonoprazan</em> Fumarate
  • HY-100007A
    Vonoprazan hydrochloride

    TAK-438 hydrochloride

    		 Proton Pump Bacterial Infection Endocrinology
    Vonoprazan hydrochloride, a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan hydrochloride inhibits H +,K +-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan hydrochloride is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan hydrochloride can be used for eradication of Helicobacter pylori .
    <em>Vonoprazan</em> hydrochloride
  • HY-Z3421S1
    Vonoprazan-d4 fumarate

    		Isotope-Labeled Compounds Others
    Vonoprazan-d4 (fumarate) is deuterium labeled 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate  (Vonoprazan Impurity）.
    <em>Vonoprazan</em>-d4 fumarate
  • HY-Z3421S
    Vonoprazan-d3 fumarate

    		Isotope-Labeled Compounds Others
    Vonoprazan-d3 (fumarate) is the deuterium labeled Fmoc-Cys(Trt)-OH[1].
    <em>Vonoprazan</em>-d3 fumarate
  • HY-Z2106S
    Vonoprazan impurity 11-d5 fumarate

    		Drug Metabolite Isotope-Labeled Compounds Others
    Vonoprazan impurity 11-d5 (fumarate) is deuterium labeled 1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylmethanamine (Vonoprazan Impurity).
    <em>Vonoprazan</em> impurity 11-d5 fumarate
  • HY-W728503S
    N-Nitroso Vonoprazan-13C,d3

    		Isotope-Labeled Compounds Infection
    N-Nitroso Vonoprazan-13C,d3 is the 13C- and deuterium labeled N-Nitroso Vonoprazan. N-Nitroso Vonoprazan is an impurity of Vonoprazan .
    N-Nitroso <em>Vonoprazan</em>-13C,d3
  • HY-Y0607S
    4-Nitrobenzoic acid-d4

    		Isotope-Labeled Compounds Others
    4-Nitrobenzoic acid-d4 is the deuterium labeled 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate  (Vonoprazan Impurity）[1].
    4-Nitrobenzoic acid-d4

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