Search Result
Results for "
air
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
2
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-118282
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PGE synthase
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Endocrinology
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mPGES-1-IN-2 (compound III) is a benzimidazole-based mPGES-1 inhibitor that also inhibits adipophysin PGD synthase (I-PGDS) (5 μM, IR=60 %). mPGES-1-IN-2 reduces PGE2 production and tends to reduce levels of other prostaglandins. mPGES-1-IN-2 effectively inhibits acute inflammation in an air sac model stimulated by Carrageenan (HY-125474) in mice .
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- HY-133154
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Cair; 4-Carboxy-air
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Endogenous Metabolite
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Infection
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Carboxyaminoimidazole ribotide (CAIR) is a metabolite of E. coli. Carboxyaminoimidazole ribotide can be used to detect distinctive features of E. coli PurE active site and synthesis fungal de novo purine .
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- HY-106560
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COX
SARS-CoV
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Inflammation/Immunology
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Proglumetacin is an orally active and potent cyclo-oxygenase inhibitor. Proglumetacin can inhibits SARS-CoV Mpro (main protease of the SARS-CoV-2), with an AC50 of 8.9 μM (activity concentration at half maximal activity). Proglumetacin has anti-inflammatory activity, can be used for inflammation (such as Rheumatoid arthritis, and Allergic air pouch inflammation) research[1][2][3].
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- HY-133155
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Endogenous Metabolite
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Metabolic Disease
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5-Aminoimidazole ribonucleotide (AIR) is an intermediate in the biosynthesis of purines, as AIR is further modified by additional enzymes to eventually produce inosine monophosphate (IMP), which can then be converted into the purine bases adenine (A) and guanine (G) .
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- HY-N9208
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Others
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Others
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Sarmentocymarin can be isolated from the air-dried powd. roots of Cryptolepis buchanani Roem .
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- HY-N1606
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Others
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Others
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17α-Thevebioside is the compound isolated from air-dried leaves of Cerbera manghas and C. odollam .
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- HY-U00087
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Bacterial
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Infection
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Tosylchloramide sodium trihydrate (Chloramine T sodium trihydrate) is a disinfectant agent widely used in laboratories, kitchens and hospitals. It is also used as a biocide in air fresheners and deodorants.
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- HY-N12256
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Others
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Others
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Cis-Emodin bianthrone (compound 4) is a highly condensed oxygen of emodin anthrone. Cis-Emodin bianthrone stable in acetone solution in air .
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- HY-N12840
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Others
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Metabolic Disease
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Logmalicid B is an iridoid glycoside compound that can be isolated from Cornus officinalis and can be used in diabetes research .
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- HY-N10133
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3′-Prenylnaringenin
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Bacterial
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Others
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Licoflavanone (compopund 2) is a flavanone. Licoflavanone can be isolated from the MeOH extract of Air-dried leaves of G. glabra var. typica. Licoflavanone has antibacterial activity .
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- HY-N1646
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2β,16α-dihydroxy-ent-kaurane 2-O-β-D-allopyranoside
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Others
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Others
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2,16-Kauranediol 2-O-β-D-allopyranoside (compound 26) is a natural product that can be isolated from the air-dried fronds of Pteris cretica .
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- HY-109519
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Others
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Others
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Simethicone is an orally active defoamer. Simethicone reduces the surface tension of air bubbles in the gastrointestinal tract, causing them to be expelled by vomiting, exhalation or absorption into the bloodstream. Simethicone has potential applications in flatulence and colic .
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- HY-B1855
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Epoxyheptachlor
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Biochemical Assay Reagents
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Others
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(±)-cis-Heptachlor epoxides, are degradation products of heptachlor that can occur in or on soil and crops when treated with heptachlor, a pesticide. Heptachlor is readily formed upon exposure to air. Everett CJ, Thompson OM. Environmental Health Pastor. 2015;30(2):93-7.
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- HY-W251598C
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Sodium hydrogen carbonate for cell culture; Soda bicarbonate for cell culture
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Biochemical Assay Reagents
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Others
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Sodium bicarbonate, for cell culture, an inorganic salt, is neutral to slightly alkaline. And it is susceptible to moisture and decomposition in the air. Sodium bicarbonate is widely used in food, pharmaceutical, cosmetics and other fields, the main uses include buffer, seasoning, disinfectant, pharmaceutical and proton gradient regulator. Sodium bicarbonate is also commonly used as an antacid to suppress gastrointestinal disorders, neutralize stomach acid and reduce stomach discomfort.
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- HY-N7155
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Reactive Oxygen Species
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Inflammation/Immunology
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2,4,7-Trihydroxy-9,10-dihydrophenanthrene is a dihydrophenanthrene derivative that can be isolated from the air-dried whole plant of Pholidota chinensis Lindl.. 2,4,7-Trihydroxy-9,10-dihydrophenanthrene shows potent activities of IC50 at 16.2 μM in DPPH radical-scavenging assay .
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- HY-N9814
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NO Synthase
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Inflammation/Immunology
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Shanciol B, isolated from the ethyl acetate extract of the air-dried whole plant of Pholidota imbricate Hook, inhibits nitric oxide (NO) production and 1,1-diphenyl-2-picrylhydrazil (DPPH) radical scavenging activity . Shanciol B is a microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor with anti-inflammatory activity .
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- HY-139874
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CXCR
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Inflammation/Immunology
Cancer
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CXCR2 antagonist 3 (compound 11h) is a potent antagonist of CXC chemokine receptor 2 (CXCR2). CXCR2 antagonist 3 demonstrates double-digit nanomolar potencies against CXCR2 and significantly inhibited neutrophil infiltration into the air pouch. CXCR2 antagonist 3 reduces the infiltration of neutrophils and MDSCs and enhance the infiltration of CD3 + T lymphocytes into the Pan02 tumor tissues .
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- HY-W111375
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Biochemical Assay Reagents
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Others
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(E)-Pent-2-enal has a pungent fruity odor. This compound is commonly used in the flavor and fragrance industry because of its strong aroma, often described as fresh and green. Furthermore, (E)-Pent-2-enal can be used as an intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Its unique chemical properties make it an important ingredient in many commercial products, including perfumes, air fresheners and cleaners.
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- HY-Y0756
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Sodium hydrogen carbonate
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Biochemical Assay Reagents
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Others
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Sodium bicarbonate, also known as baking soda, sodium bicarbonate, or sodium bicarbonate, is neutral to slightly alkaline. And it is susceptible to moisture and decomposition in the air. Sodium bicarbonate is widely used in food, pharmaceutical, cosmetics and other fields, the main uses include buffer, seasoning, disinfectant, pharmaceutical and proton gradient regulator. In the food industry, it is often used as a flour starter or leavening agent to make food swell up and become softer. Sodium bicarbonate is also commonly used as an antacid to suppress gastrointestinal disorders, neutralize stomach acid and reduce stomach discomfort.
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- HY-120878
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CXCR
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Inflammation/Immunology
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CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist (IC50=5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and >1900-fold selectivity over all other chemokine receptors. CXCR2-IN-2 inhibits human whole blood Gro-α induced CD11b expression with an IC50 of 0.04 μM .
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- HY-N0709S1
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Bacterial
Fungal
Isotope-Labeled Compounds
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Cancer
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Coumarin-d6 is deuterated labeled trans-2-Undecenal (HY-W127505). Trans-2-UndecenalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2-UndecenalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
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- HY-N2435
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COX
Apoptosis
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Cancer
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[8]-Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC50=5 μM), anti-cancer and anti-inflammatory activity. [8]-Shogaol inhibited COX-2 (IC50=17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC50=5 μM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA).
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- HY-N1369S1
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Calcium Channel
Isotope-Labeled Compounds
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Neurological Disease
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Menthol-d2 is deuterated labeled trans-2,cis-6-Nonadienal (HY-W127515). Trans-2, cis-6-NonadienalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2, cis-6-NonadienalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
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- HY-110112
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Integrin
Apoptosis
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Cardiovascular Disease
Inflammation/Immunology
Cancer
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BTT-3033 is an orally active conformation-selective inhibitor of α2β1 (EC50: 130 nM) by binding to the α2I domain. BTT-3033 inhibits platelet binding to collagen Ⅰ and cell proliferation, and induces cell apoptosis. BTT-3033 can be used in the research of prostate cancer, inflammation and cardiovascular disease .
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- HY-12764
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6-OAU
1 Publications Verification
GTPL5846
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GPR84
ERK
Bacterial
Antibiotic
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Inflammation/Immunology
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6-OAU (GTPL5846) (6-n-octylaminouracil) is an GPR84 (G protein-coupled receptor 84) agonist, with an EC50 value of 105 nM. 6-OAU works as a chemoattractant to both PMNs and macrophages, and amplifies the proinflammatory cytokine IL-8, shows proinflammatory function. 6-OAU also displays anti-bacterial function .
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HY-L100
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130 compounds
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Cancer is a multi-step process which involves initiation, promotion and progression. Chemical carcinogens can alter any of these processes to induce their carcinogenic effects. People are continuously exposed exogenously to varying amounts of chemicals that have been shown to have carcinogenic or mutagenic properties in experimental systems. Exposure can occur exogenously when these agents are present in food, air or water, and also endogenously when they are products of metabolism or pathophysiologic states such as inflammation. The administration of chemical carcinogens is one of the most commonly used methods to induce tumors in several organs in laboratory animals in order to study oncologic diseases of humans.
MCE offers a unique collection of 130 chemical carcinogens which have been identified with carcinogenic activity either in humans or in animal models. MCE Tumorigenesis-Related Compound Library is a powerful tool for studying oncologic diseases of humans. Standard opration based on safety data sheet will not cause harm to the body.
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Cat. No. |
Product Name |
Type |
-
- HY-W251598C
-
Sodium hydrogen carbonate for cell culture; Soda bicarbonate for cell culture
|
Buffer Reagents
|
Sodium bicarbonate, for cell culture, an inorganic salt, is neutral to slightly alkaline. And it is susceptible to moisture and decomposition in the air. Sodium bicarbonate is widely used in food, pharmaceutical, cosmetics and other fields, the main uses include buffer, seasoning, disinfectant, pharmaceutical and proton gradient regulator. Sodium bicarbonate is also commonly used as an antacid to suppress gastrointestinal disorders, neutralize stomach acid and reduce stomach discomfort.
|
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- HY-W111375
-
|
Biochemical Assay Reagents
|
(E)-Pent-2-enal has a pungent fruity odor. This compound is commonly used in the flavor and fragrance industry because of its strong aroma, often described as fresh and green. Furthermore, (E)-Pent-2-enal can be used as an intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Its unique chemical properties make it an important ingredient in many commercial products, including perfumes, air fresheners and cleaners.
|
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- HY-Y0756
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Sodium hydrogen carbonate
|
Biochemical Assay Reagents
|
Sodium bicarbonate, also known as baking soda, sodium bicarbonate, or sodium bicarbonate, is neutral to slightly alkaline. And it is susceptible to moisture and decomposition in the air. Sodium bicarbonate is widely used in food, pharmaceutical, cosmetics and other fields, the main uses include buffer, seasoning, disinfectant, pharmaceutical and proton gradient regulator. In the food industry, it is often used as a flour starter or leavening agent to make food swell up and become softer. Sodium bicarbonate is also commonly used as an antacid to suppress gastrointestinal disorders, neutralize stomach acid and reduce stomach discomfort.
|
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- HY-B1855
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Epoxyheptachlor
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Biochemical Assay Reagents
|
(±)-cis-Heptachlor epoxides, are degradation products of heptachlor that can occur in or on soil and crops when treated with heptachlor, a pesticide. Heptachlor is readily formed upon exposure to air. Everett CJ, Thompson OM. Environmental Health Pastor. 2015;30(2):93-7.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P5519
-
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Peptides
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Others
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[Thr28, Nle31]-Cholecystokinin (25-33) is a biological active peptide. (Cholecystokinin (CCK) acts both as a hormone and a neurotransmitter and is found in the GI system and the central nervous system. It is a satiety peptide that inhibits food intake.This Cholecystokinin (CCK) analog retains all the bioactivities of CCK8, but was found to be remarkably more stable in acidic media and unaffected by air oxidation due to Met replacements (Thr 28 and Nle31 were substituted for Methionine). The predominant conformation contains a gamma-turn centered on Thr4, separated by Gly5 from a helical segment that comprises the C-terminal residues.)
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-N0709S1
-
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Coumarin-d6 is deuterated labeled trans-2-Undecenal (HY-W127505). Trans-2-UndecenalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2-UndecenalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
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- HY-N1369S1
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Menthol-d2 is deuterated labeled trans-2,cis-6-Nonadienal (HY-W127515). Trans-2, cis-6-NonadienalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2, cis-6-NonadienalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
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