Search Result

Results for "

anthelmintic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Amyloid-β (1) Antibiotic (14) Apoptosis (11) Autophagy (4) Bacterial (12) BCRP (2) Caspase (1) CDK (1) Endogenous Metabolite (2) Ferroptosis (2) Fungal (5) GABA Receptor (1) Glucosidase (2) HIF/HIF Prolyl-Hydroxylase (3) HSV (2) Influenza Virus (1) Interleukin Related (1) Isotope-Labeled Compounds (4) MDM-2/p53 (3) Microtubule/Tubulin (9) Mitochondrial Metabolism (2) nAChR (11) Notch (1) Oxidative Phosphorylation (2) P-glycoprotein (2) Parasite (71) Reactive Oxygen Species (3) STAT (3) VEGFR (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (1) Infection (75) Inflammation/Immunology (9) Metabolic Disease (2) Neurological Disease (8)

By Targets:

5-HT Receptor (1)

Amyloid-β (1)

Antibiotic (14)

Apoptosis (11)

Autophagy (4)

Bacterial (12)

BCRP (2)

Caspase (1)

CDK (1)

Endogenous Metabolite (2)

Ferroptosis (2)

Fungal (5)

GABA Receptor (1)

Glucosidase (2)

HIF/HIF Prolyl-Hydroxylase (3)

HSV (2)

Influenza Virus (1)

Interleukin Related (1)

Isotope-Labeled Compounds (4)

MDM-2/p53 (3)

Microtubule/Tubulin (9)

Mitochondrial Metabolism (2)

nAChR (11)

Notch (1)

Oxidative Phosphorylation (2)

P-glycoprotein (2)

Parasite (71)

Reactive Oxygen Species (3)

STAT (3)

VEGFR (1)

By Research Areas:

Cancer (20)

Cardiovascular Disease (1)

Infection (75)

Inflammation/Immunology (9)

Metabolic Disease (2)

Neurological Disease (8)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-123305

5-Hydroxymebendazole	Parasite	Others
5-Hydroxymebendazole is the one metabolite of Benzimidazoles. Benzimidazoles are safe, broad-spectrum anthelmintic agents and are widely used for prevention and treatment of parasitic infections in food-producing animals .

HY-137141

16-Keto Aspergillimide

SB202327
Parasite Infection

16-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664 .
HY-138194

Destomycin B

A-16316-C
Antibiotic Fungal Infection

Destomycin B (A-16316-C) is an antibiotic, and is active against fungi. Destomycin B also has anthelmintic activity .
HY-122765

Luxabendazole

HOE 216V
Parasite Infection

Luxabendazole (HOE 216V) is an effective anthelmintic against trematodes, cestodes and nematodes .

16-Keto Aspergillimide SB202327	Parasite	Infection
16-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664 .

Destomycin B A-16316-C	Antibiotic Fungal	Infection
Destomycin B (A-16316-C) is an antibiotic, and is active against fungi. Destomycin B also has anthelmintic activity .

Luxabendazole HOE 216V	Parasite	Infection
Luxabendazole (HOE 216V) is an effective anthelmintic against trematodes, cestodes and nematodes .

HY-112542

Nemadectin CL-287088; LL-F28249 α	Parasite Antibiotic	Infection
Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity .

HY-124498

Oxantel CP-14445	nAChR Parasite	Infection
Oxantel (CP-14445), a m-oxyphenol derivative of Pyrantel (HY-12641), is a N-subtype AChR agonist. Oxantel is an anthelmintic, with excellent trichuricidal properties .

HY-Y0055

Phenothiazine 1 Publications Verification Thiodiphenylamine	Antibiotic Fungal Bacterial Parasite	Infection Neurological Disease
Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases .

HY-N8378

Clonostachydiol

Others Infection

Clonostachydiol is an anthelmintic macrodiolide from the fungus Clonostachys cylindrospora (strain FH-A 6607) .

Clonostachydiol	Others	Infection
Clonostachydiol is an anthelmintic macrodiolide from the fungus Clonostachys cylindrospora (strain FH-A 6607) .

HY-12361

PF 1022A 1 Publications Verification	Parasite	Infection
PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against *Ascaridia galli* in chickens. PF 1022A also can be used for angiostrongyliasis research .

HY-W049875

Nitroxynil	Parasite	Infection
Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica .

HY-113715

Niclofolan BAY 9015; Menichlopholan; Menichlofolan; Bilevon	Parasite	Infection
Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection .

HY-W011239

Fenbendazole sulfone Oxfendazole sulfone; FBZ-SO2	Parasite	Infection
Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent .

HY-19054

CGP-20376	Parasite	Infection
CGP-20376, a 5-methoxyl-6-dithiocarbamic-S- (2-carboxy-ethyl) ester derivative of Benzothiazole (HY-W012634), is an orally active and potent antifilarial drug. CGP-20376 has anthelmintic activity .

HY-B1636

Dithiazanine iodide	Parasite	Infection
Dithiazanine iodide is an effective broad-spectrum *anthelmintic*. Dithiazanine iodide can be used for the research of trichuriasis, strongyloidiasis, enterobiasis, ascariasis, and hookworm infection. Dithiazanine iodide is also a cyanine dye .

HY-124874

(rel)-Asperparaline A (rel)-Aspergillimide; (rel)-VM55598	nAChR	Neurological Disease
(rel)-Asperparaline A ((rel)-Aspergillimide), an anthelmintic metabolite, is isolated from okara that has been fermented with Aspergillus japonicas JV-23. (rel)-Asperparaline A is also a potent and selective antagonist of nAChR. (rel)-Asperparaline A exhibits paralytic activity in silk worms .

HY-W158234

N-Methylbenzo[d]oxazol-2-amine	Parasite	Infection
N-Methylbenzo[d]oxazol-2-amine (compound 1) is an anthelmintic activity and lower cytotoxicity against T. spiralis adult worm. N-Methylbenzo[d]oxazol-2-amine up-regulates the metabolism of purine, pyrimidine and down-regulates sphingolipid metabolism .

HY-N10368

Shinjulactone M	Parasite	Infection Neurological Disease Inflammation/Immunology
Shinjulactone M is a quassinoid isolated from various parts of Ailanthus species. Ailanthus, an important genus of the Simaroubaceae family, can be used as an febrifuge (antimalarial) and anthelmintic, and is given for the research of chronic bronchitis, epilepsy and asthma .

HY-W265961

Squoxin ST1859; 1,1′-Methylenedi-2-naphthol	Amyloid-β	Neurological Disease Inflammation/Immunology
Squoxin (ST1859) is an antiamyloid agent that specifically binds to Aβ1-42 and prevents the aggregation and fibril formation of Aβ. Squoxin crosses the blood-brain barrier (BBB) and has anthelmintic activity and anti-inflammatory properties .

HY-B0986

Hexylresorcinol 4-Hexylresorcinol	Parasite Bacterial Apoptosis Glucosidase Endogenous Metabolite	Infection Metabolic Disease Cancer
Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage .

HY-B0217

Nitazoxanide Maximum Cited Publications 8 Publications Verification NTZ; NSC 697855	Parasite Influenza Virus Autophagy	Infection Cancer
Nitazoxanide (NTZ), an *anthelmintic* agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC₅₀ of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .

HY-121618

α-Thujone	GABA Receptor Reactive Oxygen Species Parasite Apoptosis Autophagy	Infection Neurological Disease Cancer
α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC₅₀ for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier .

HY-B0294

Flubendazole 5+ Cited Publications	Parasite Microtubule/Tubulin STAT MDM-2/p53 Apoptosis Autophagy	Infection Cancer
Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites .

HY-B0986R

Hexylresorcinol (Standard)	Parasite Bacterial Apoptosis Glucosidase Endogenous Metabolite	Infection Metabolic Disease Cancer
Hexylresorcinol (Standard) is the analytical standard of Hexylresorcinol. This product is intended for research and analytical applications. Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage .

HY-B0217R

Nitazoxanide (Standard)		Infection Cancer
Nitazoxanide (Standard) is the analytical standard of Nitazoxanide. This product is intended for research and analytical applications. Nitazoxanide (NTZ), an *anthelmintic* agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC₅₀ of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .

HY-127156

Hikizimycin

Anthelmycin
Bacterial Infection

Hikizimycin is a potent anthelmintic and antibacterial natural product.

Hikizimycin Anthelmycin	Bacterial	Infection
Hikizimycin is a potent anthelmintic and antibacterial natural product.

HY-B0294R

Flubendazole (Standard)	Parasite Microtubule/Tubulin STAT MDM-2/p53 Apoptosis Autophagy	Infection Cancer
Flubendazole (Standard) is the analytical standard of Flubendazole. This product is intended for research and analytical applications. Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites .

HY-118494

Ascaridole

Parasite Infection

Ascaridole is an anthelmintic and also has antimalarial activity .

Ascaridole	Parasite	Infection
Ascaridole is an anthelmintic and also has antimalarial activity .

HY-B0413

Fenbendazole 5 Publications Verification	Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic	Infection
Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .

HY-B1073

Morantel tartrate

Parasite Infection

Morantel tartrate is a broad spectrum anthelmintic, effective and low toxicity.
HY-B0244S

Praziquantel-d11

Isotope-Labeled Compounds Parasite Infection

Praziquantel-d₁₁ is the deuterium labeled Praziquantel, which is an anthelmintic.
HY-101476

Emodepside

Bay 44-4400
Parasite Infection

Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
HY-U00295

Melarsonyl

Melarsonic acid
Parasite Infection

Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.
HY-B1313

Lobendazole

Parasite Infection

Lobendazole is a potent anthelmintic. Lobendazole inhibits Giardia intestinalis strains .

Morantel tartrate	Parasite	Infection
Morantel tartrate is a broad spectrum anthelmintic, effective and low toxicity.

Praziquantel-d11	Isotope-Labeled Compounds Parasite	Infection
Praziquantel-d₁₁ is the deuterium labeled Praziquantel, which is an anthelmintic.

Emodepside Bay 44-4400	Parasite	Infection
Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.

Melarsonyl Melarsonic acid	Parasite	Infection
Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.

Lobendazole	Parasite	Infection
Lobendazole is a potent anthelmintic. Lobendazole inhibits Giardia intestinalis strains .

HY-B0413S

Fenbendazole-d3 2 Publications Verification	HIF/HIF Prolyl-Hydroxylase Parasite Microtubule/Tubulin Antibiotic	Infection
Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].

HY-125159

Derquantel

PF-00520904
Parasite Infection

Derquantel is a potent anthelmintic. Derquantel causes flaccid paralysis and expulsion of nematodes .

Derquantel PF-00520904	Parasite	Infection
Derquantel is a potent anthelmintic. Derquantel causes flaccid paralysis and expulsion of nematodes .

HY-B0413R

Fenbendazole (Standard)	Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic	Infection
Fenbendazole (Standard) is the analytical standard of Fenbendazole. This product is intended for research and analytical applications. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .

HY-B2186

Piperazine adipate

Parasite Infection

Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.

Piperazine adipate	Parasite	Infection
Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.

HY-U00295A

Melarsonyl dipotassium Melarsonic acid dipotassium	Parasite	Infection
Melarsonyl dipotassium (Melarsonic acid dipotassium) is an anthelmintic agent which can inhibit parasite potently .

HY-123693

ML358	Others	Inflammation/Immunology
ML358 is a first in class, potent, and selective inhibitor of the SKN-1 pathway (IC₅₀=0.24 μM). ML358 sensitizes the model nematode C. elegans to oxidants and anthelmintic. ML358 potentially used as adjuvants to increase the efficacy and useful life of current anthelmintics .

HY-12639

Bephenium

Parasite Infection

Bephenium is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.

Bephenium	Parasite	Infection
Bephenium is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.

HY-12785S

Albendazole sulfoxide D3 Ricobendazole d₃; Albendazole oxide d₃	Parasite	Inflammation/Immunology
Albendazole sulfoxide-d₃ is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.

HY-12643

Eprinomectin MK-397	Parasite Bacterial	Infection
Eprinomectin(MK-397) is an avermectin selected for development as a topical endectocide; has anthelmintic, insecticidal and miticidal activity.

HY-12639A

Bephenium (hydroxynaphthoate)	Parasite	Infection
Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.

HY-17597

Febantel

Parasite Infection

Febantel is an anthelmintic for veterinary use on dogs, cats, cattle, sheep, goats, pig and poultry against roundworms and tapeworms.

Febantel	Parasite	Infection
Febantel is an anthelmintic for veterinary use on dogs, cats, cattle, sheep, goats, pig and poultry against roundworms and tapeworms.

HY-N0337

Eugenol 4 Publications Verification	Bacterial Parasite Reactive Oxygen Species Apoptosis Ferroptosis	Infection Inflammation/Immunology Cancer
Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.

HY-115364

Parbendazole 5+ Cited Publications SKF 29044	Microtubule/Tubulin Parasite	Infection
Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC₅₀ of 530 nM, and exhibits a broad-spectrum anthelmintic activity.

HY-13666

Levamisole hydrochloride 3 Publications Verification (-)-Tetramisole hydrochloride	Parasite HSV	Infection Neurological Disease
Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV.

HY-14774

Monepantel AAD1566	nAChR	Cancer
Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.

HY-B0294S

Flubendazole-d3	Parasite Microtubule/Tubulin Apoptosis	Infection Cancer
Flubendazole-d₃ is the deuterium labeled Flubendazole. Flubendazole is a safe and efficacious anthelmintic agent, which is widely used for anthelmintic to human, rodents and ruminants. Flubendazole exerts anticancer activities by mechanisms including inhibition of microtubule function. Flubendazole induces p53-mediated apoptosis and arrests G2/M cell cycle[1][2].

HY-121477

Resorantel	Parasite	Infection
Resorantel is an anthelmintic . Resorantel is used in the research of paramphistomiasis in cattle and sheep and has also been used for the research of G. aegypticus .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-12361

PF 1022A 1 Publications Verification	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against *Ascaridia galli* in chickens. PF 1022A also can be used for angiostrongyliasis research .

HY-137141

16-Keto Aspergillimide SB202327	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
16-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664 .

HY-138194

Destomycin B A-16316-C	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Fungal
Destomycin B (A-16316-C) is an antibiotic, and is active against fungi. Destomycin B also has anthelmintic activity .

HY-112542

Nemadectin CL-287088; LL-F28249 α	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Anti-parasitic Disease Research Disease Research Fields	Parasite Antibiotic
Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity .

HY-N8378

Clonostachydiol	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Others
Clonostachydiol is an anthelmintic macrodiolide from the fungus Clonostachys cylindrospora (strain FH-A 6607) .

HY-124874

(rel)-Asperparaline A (rel)-Aspergillimide; (rel)-VM55598	Alkaloids Microorganisms Pyrrole Alkaloids Source classification	nAChR
(rel)-Asperparaline A ((rel)-Aspergillimide), an anthelmintic metabolite, is isolated from okara that has been fermented with Aspergillus japonicas JV-23. (rel)-Asperparaline A is also a potent and selective antagonist of nAChR. (rel)-Asperparaline A exhibits paralytic activity in silk worms .

HY-N10368

Shinjulactone M	Infection Simaroubaceae Ailanthus altissima (Mill.) Swingle Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Inflammation/Immunology Disease Research Fields	Parasite
Shinjulactone M is a quassinoid isolated from various parts of Ailanthus species. Ailanthus, an important genus of the Simaroubaceae family, can be used as an febrifuge (antimalarial) and anthelmintic, and is given for the research of chronic bronchitis, epilepsy and asthma .

HY-B0986

Hexylresorcinol 4-Hexylresorcinol	Infection Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	Parasite Bacterial Apoptosis Glucosidase Endogenous Metabolite
Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage .

HY-121618

α-Thujone	Infection Other Monoterpenes Platycladus orientalis (Linn.) Franco Cupressaceae Classification of Application Fields Neurological Disease Terpenoids Source classification Plants Disease Research Fields	GABA Receptor Reactive Oxygen Species Parasite Apoptosis Autophagy
α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC₅₀ for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier .

HY-B0986R

Hexylresorcinol (Standard)	Structural Classification Source classification Phenols Polyphenols Endogenous metabolite	Parasite Bacterial Apoptosis Glucosidase Endogenous Metabolite
Hexylresorcinol (Standard) is the analytical standard of Hexylresorcinol. This product is intended for research and analytical applications. Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage .

HY-118494

Ascaridole	Structural Classification Natural Products Source classification Plants Dysphania ambrosioides (Linnaeus) Mosyakin & Clemants Chenopodiaceae	Parasite
Ascaridole is an anthelmintic and also has antimalarial activity .

HY-N0337

Eugenol 4 Publications Verification	Structural Classification Classification of Application Fields Source classification Plants Syzygium aromaticum Monophenols Microorganisms Simple Phenylpropanols Phenols Myrtaceae Phenylpropanoids Inflammation/Immunology Disease Research Fields Cancer	Bacterial Parasite Reactive Oxygen Species Apoptosis Ferroptosis
Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.

HY-N3014

Bruceine D 3 Publications Verification	Infection Simaroubaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr.	Notch Apoptosis Parasite
Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity . Bruceine D has strong *anthelmintic* activity against D. intermedius with an EC₅₀ value of 0.57 mg/L .

Cat. No.	Product Name	Chemical Structure

HY-B0244S

Praziquantel-d11

Praziquantel-d₁₁ is the deuterium labeled Praziquantel, which is an anthelmintic.

HY-B0413S

Fenbendazole-d3

2 Publications Verification

Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].

HY-12785S

Albendazole sulfoxide D3

Albendazole sulfoxide-d₃ is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.

HY-B0294S

Flubendazole-d3
Flubendazole-d₃ is the deuterium labeled Flubendazole. Flubendazole is a safe and efficacious anthelmintic agent, which is widely used for anthelmintic to human, rodents and ruminants. Flubendazole exerts anticancer activities by mechanisms including inhibition of microtubule function. Flubendazole induces p53-mediated apoptosis and arrests G2/M cell cycle[1][2].

HY-N0337S

Eugenol-d3
Eugenol-d₃ is the deuterium labeled Eugenol. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.

HY-115364S

Parbendazole-d3
Parbendazole-d₃ is the deuterium labeled Parbendazole. Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity.

HY-14774S

(Rac)-Monepantel-d5
(Rac)-Monepantel-d₅ is deuterium labeled Monepantel. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.

HY-14774S1

(Rac)-Monepantel sulfone-d5
(Rac)-Monepantel sulfone-d₅ is deuterium labeled Monepantel. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.

HY-13666S

Levamisole-d5 hydrochloride
Levamisole-d₅ (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV[1][2].

HY-Y0055S

Phenothiazine-d8
Phenothiazine-d₈ is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].

HY-123305S

5-Hydroxymebendazole-d3

5-Hydroxymebendazole-d₃ is a deuterium labeled 5-Hydroxymebendazole. 5-Hydroxymebendazole is the one metabolite of Benzimidazoles[1].

HY-126057S

(R)-Praziquantel-d11
(R)-Praziquantel-d₁₁ is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].

HY-B0497S1

Niclosamide-13C6
Niclosamide- ¹³C₆ is the ¹³C₆ labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.

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