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Results for "

antidotal

" in MedChemExpress (MCE) Product Catalog:

29

Inhibitors & Agonists

1

Fluorescent Dye

1

Biochemical Assay Reagents

2

Peptides

5

Natural
Products

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6612
    D-Glucuronic acid
    1 Publications Verification

    		 Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    D-Glucuronic acid is an important intermediate isolated from many gums, which has an anti-inflammatory effect for the skin. D-Glucuronic acid and its derivative glucuronolactone are as a liver antidote in the prophylaxis of human health, and its derivatives have antitumor activity .
    D-Glucuronic acid
  • HY-N6608
    Physostigmine

    Eserine

    		 Cholinesterase (ChE) Neurological Disease
    Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning .
    Physostigmine
  • HY-B1266
    Physostigmine salicylate

    Eserine salicylate

    		 Cholinesterase (ChE) Neurological Disease
    Physostigmine salicylate (Eserine salicylate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine salicylate crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine salicylate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine salicylate is also an antidote for anticholinergic poisoning .
    Physostigmine salicylate
  • HY-B1738A
    Pralidoxime iodide

    		Cholinesterase (ChE) Neurological Disease
    Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning .
    Pralidoxime iodide
  • HY-128370
    Calcium trinatrium diethylenetriaminepentaacetic acid hydrate

    Ca-DTPA trisodium salt hydrate

    		 CMV Infection
    Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic inhibitor of CMV replication .
    Calcium trinatrium diethylenetriaminepentaacetic acid hydrate
  • HY-B0876
    Fomepizole
    3 Publications Verification

    4-Methylpyrazole

    		 Cytochrome P450 Metabolic Disease
    Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole has the potential for an antidote for ethylene glycol or methanol poisoning .
    Fomepizole
  • HY-145909
    BRD4 Inhibitor-17

    		Epigenetic Reader Domain Cancer
    BRD4 Inhibitor-17 (Compound 5i) is a potent inhibitor of BRD4 with an IC50 of 0.33 μM. BRD4 Inhibitor-17 plays crucial role in regulating transcription of inflammatory, proliferation and cell cycle genes. BRD4 Inhibitor-17 serves as potential antidotes for arsenicals .
    BRD4 Inhibitor-17
  • HY-B0568
    Deferiprone
    Maximum Cited Publications
    32 Publications Verification

    		 Ferroptosis HCV Apoptosis COX Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer, cardiovascular disease, infection, inflammation, and neurological disease study .
    Deferiprone
  • HY-146959
    K203

    		Cholinesterase (ChE) Neurological Disease
    K203 is a potent reactivator of tabun-inhibited AChE. K203 is a crucial antidote used for the organophosphate intoxication .
    K203
  • HY-D1387
    Naloxone fluorescein acetate

    		Fluorescent Dye Neurological Disease
    Naloxone fluorescein acetate is the fluorescent-derivative of Naloxone. Naloxone is an opioid antagonist. Naloxone is the antidote for reversing the effects of an opioid overdose .
    Naloxone fluorescein acetate
  • HY-124750
    NecroX-7

    		TNF Receptor Interleukin Related Toll-like Receptor (TLR) Reactive Oxygen Species Cardiovascular Disease Inflammation/Immunology
    NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research .
    NecroX-7
  • HY-B1326
    Bemegride

    3-Ethyl-3-methylglutarimide; Bemegrid

    		 GABA Receptor Neurological Disease
    Bemegride (3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning .
    Bemegride
  • HY-128454S
    Dimethyl trisulfide-d6

    		Endogenous Metabolite Others
    Dimethyl trisulfide-d6 is deuterium labeled Dimethyl trisulfide (HY-128454). Dimethyl trisulfide is a cyanide antidote .
    Dimethyl trisulfide-d6
  • HY-128454
    Dimethyl trisulfide

    		Endogenous Metabolite Others
    Dimethyl trisulfide is an organic chemical compound and the simplest organic trisulfide found in garlic, onion, broccoli, and similar plants. Dimethyl trisulfide is a cyanide antidote .
    Dimethyl trisulfide
  • HY-106594A
    Prussian blue insoluble

    Iron(III) ferrocyanide; Milori blue

    		 Bacterial Infection Others Cancer
    Prussian blue insoluble (Iron(III) ferrocyanide) is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue insoluble (Iron(III) ferrocyanide) has anticancerous and antibacterial properties. Prussian blue insoluble (Iron(III) ferrocyanide) can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI). Prussian blue insoluble can be used for contrast agents, antidotes and cancer research .
    Prussian blue insoluble
  • HY-B0373
    Tiopronin

    		Others Metabolic Disease
    Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders .
    Tiopronin
  • HY-W011108
    Obidoxime dichloride

    		Cholinesterase (ChE) Neurological Disease
    Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated .
    Obidoxime dichloride
  • HY-B1200
    Pralidoxime chloride

    2-PAM chloride

    		 Cholinesterase (ChE) Neurological Disease
    Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
    Pralidoxime chloride
  • HY-B1738
    Pralidoxime

    Pralidoxime is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime is an antidote for organophosphate poisoning .
    Pralidoxime
  • HY-B0373S1
    Tiopronin-d3

    		Isotope-Labeled Compounds Metabolic Disease
    Tiopronin-d3 is the deuterium labeled Tiopronin. Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders[1][2].
    Tiopronin-d3
  • HY-N0326
    L-Methionine

    		Endogenous Metabolite Keap1-Nrf2 Apoptosis Inflammation/Immunology Cancer
    L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity .
    L-Methionine
  • HY-157930
    TP-2

    		Others Cardiovascular Disease
    TP-2, a caltrop-like multicationic small molecule, is an antidote that can completely neutralize both unfractionated heparin (UFH) and low-molecular-weight heparins (LMWHs). TP-2 is not only superior to protamine, has higher neutralization activity, but is also biocompatible .
    TP-2
  • HY-P10131
    3BP-3940

    		FAP Cancer
    3BP-3940 is a highly potent fibroblast activation protein (FAP)-targeting peptide for theranostics. 3BP-3940 is often coupled with radionuclides for tumor diagnosis and treatment .
    3BP-3940
  • HY-N2320
    Physostigmine hemisulfate

    Eserine hemisulfate
    Physostigmine hemisulfate (Eserine hemisulfate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine hemisulfate can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine hemisulfate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine hemisulfate is also an antidote for anticholinergic poisoning .
    Physostigmine hemisulfate
  • HY-B0876A
    Fomepizole hydrochloride

    4-Methylpyrazole hydrochloride
    Fomepizole (4-Methylpyrazole) hydrochloride is a potent and orally active cytochrome P450 (CYP2E1) inhibitor. Fomepizole hydrochloride is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole hydrochloride blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole hydrochloride has the potential for an antidote for ethylene glycol or methanol poisoning .
    Fomepizole hydrochloride
  • HY-N6608S
    Physostigmine-d3

    Eserine-d3

    		 Isotope-Labeled Compounds Cholinesterase (ChE) Neurological Disease
    Physostigmine-d3 is the deuterium labeled Physostigmine. Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning[1][2][3][4].
    Physostigmine-d3
  • HY-W017457
    DL-Penicillamine

    (±)-Penicillamine

    		 Others Others
    DL-Penicillamine [(±)-Penicillamine] is a copper chelating agent. DL-Penicillamine has antidotal effects in thallotoxicosis rats when co-treated with Prussian blue (HY-106594A). DL-Penicillamine can cause pyridoxine deficiency and then induce optic axial neuritis. DL-Penicillamine can also depress primary immune response .
    DL-Penicillamine
  • HY-W749867
    Ca(Ⅱ)-EDTA disodium dihydrate

    Calcium disodium EDTA dihydrate

    		 Bacterial Infection Others
    CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis . CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning .
    Ca(Ⅱ)-EDTA disodium dihydrate
  • HY-P5297
    DOTA-CXCR4-L

    		CXCR Cancer
    DOTA-CXCR4-L is a CXCR4 targeting peptide. DOTA-CXCR4-L can be used in the study of cancers, including glioblastoma and triple-negative breast cancer .
    <em>DOTA</em>-CXCR4-L

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