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" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Inhibitory Antibodies

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-150252A
    ATIC-IN-1 acetate

    		Others Cancer
    ATIC-IN-1 (compound 14) acetate is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 acetate exhibits anti-tumor activity via reduction in cell numbers and cell division rates .
    ATIC-IN-1 acetate
  • HY-N0485
    Liensinine Diperchlorate
    5+ Cited Publications

    		 Autophagy Mitophagy Cardiovascular Disease
    Liensinine Diperchlor​ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlor​ate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlor​ate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc .
    Liensinine Diperchlorate
  • HY-150252
    ATIC-IN-1

    		Others Cancer
    ATIC-IN-1(compound 14) is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 exhibits anti-tumor activity via reduction in cell numbers and cell division rates .
    ATIC-IN-1
  • HY-RS01156
    ATIC Human Pre-designed siRNA Set A

    		Others

    ATIC Human Pre-designed siRNA Set A contains three designed siRNAs for ATIC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ATIC Human Pre-designed siRNA Set A
    ATIC Human Pre-designed siRNA Set A
  • HY-RS01126
    ATE1 Human Pre-designed siRNA Set A

    		Others

    ATE1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ATE1 Human Pre-designed siRNA Set A
    ATE1 Human Pre-designed siRNA Set A
  • HY-N1448
    Vincetoxicoside B

    		Fungal Infection
    Vincetoxicoside B shows antifungal activity .
    Vincetoxicoside B
  • HY-P990067
    Evunzekibart

    ATOR-1017

    		 TNF Receptor Cancer
    Evunzekibart (ATOR-1017) is an Fc-γ receptor conditional 4-1BB agonist and IgG4-type antibody. Evunzekibart can be used as monotherapy or in combination with anti-PD1 to exert anticancer activity.
    Evunzekibart
  • HY-141324
    Tetraethyl butane-​1,​4-​diylbis(phosphoramid​ate)

    		PROTAC Linkers Cancer
    Tetraethyl butane-​1,​4-​diylbis(phosphoramid​ate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    Tetraethyl butane-​1,​4-​diylbis(phosphoramid​<em>ate</em>)
  • HY-E70121
    Succinyl-CoA synthetase

    		Others Others
    Succinyl-CoA synthetase catalyzes the only substrate-level phosphoryl-ation step in the tricarboxylic acid cycle. Succinyl-CoA synthetase is a phosphate target for the activation of mitochondrial metabolism .
    Succinyl-CoA synthetase

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