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cholesterol

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0322
    Cholesterol
    15+ Cited Publications

    Liposome Estrogen Receptor/ERR Endogenous Metabolite Bacterial Metabolic Disease Cancer
    Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>
  • HY-144309

    Cytochrome P450 Neurological Disease
    Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor (IC50=8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier .
    <em>Cholesterol</em> 24-hydroxylase-IN-1
  • HY-N0322R
    Cholesterol (Standard)
    15+ Cited Publications

    Liposome Estrogen Receptor/ERR Endogenous Metabolite Bacterial Metabolic Disease Cancer
    Cholesterol (Standard) is the analytical standard of Cholesterol. This product is intended for research and analytical applications. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em> (Standard)
  • HY-W127350

    Liposome Metabolic Disease
    Cholesterol Pelargonate, a Cholesterol derivative, can be used as a triggered release liposome tested .
    <em>Cholesterol</em> Pelargonate
  • HY-N7390

    Endogenous Metabolite Metabolic Disease
    Cholesterol glucuronide is an endogenous metabolite of lipid generated in the liver by UDP glucuonyltransferase .
    <em>Cholesterol</em> glucuronide
  • HY-W127331

    Biochemical Assay Reagents Others
    Cholesterol hexanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caproic acid. Cholesterol hexanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    <em>Cholesterol</em> hexanoate
  • HY-W127351

    Biochemical Assay Reagents Others
    Cholesterol decanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and capric acid. Cholesterol decanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    <em>Cholesterol</em> decanoate
  • HY-P2879

    Endogenous Metabolite Metabolic Disease
    Cholesterol esterase, Pseudomonas is an enzyme that hydrolyzes cholesterol ester to cholesterol and free fatty acid in the intestinal lumen. Cholesterol synthesized in the acinar cells and is stored in zymogen granules. Cholesterol esterase is also known as bile salt-stimulated lipase and carboxy ester lipasea, acts function for acceleration of cholesterol absorption .
    <em>Cholesterol</em> esterase, Pseudomonas
  • HY-W127558

    Biochemical Assay Reagents Others
    Cholesterol-PEG 600 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    <em>Cholesterol</em>-PEG 600
  • HY-N0322A
    Cholesterol (Water Soluble)
    15+ Cited Publications

    Liposome Others
    Cholesterol Water Soluble can be used for the research of the effects of cholesterol on the potassium currents in inner hair cells (IHCs). Cholesterol is an integral component of the cell membrane and regulates the activity of ion channels in the lipid bilayer .
    <em>Cholesterol</em> (Water Soluble)
  • HY-N0322S7

    Isotope-Labeled Compounds Estrogen Receptor/ERR Endogenous Metabolite Endocrinology
    Cholesterol-d is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>-d1
  • HY-N0322S

    Estrogen Receptor/ERR Endogenous Metabolite Metabolic Disease
    Cholesterol-d7 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>-d7
  • HY-N0322S1

    Estrogen Receptor/ERR Endogenous Metabolite
    Cholesterol-d6 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>-d6
  • HY-N0322S6

    Estrogen Receptor/ERR Endogenous Metabolite Metabolic Disease
    Cholesterol-d4 is deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>-d4
  • HY-N0322S8

    Isotope-Labeled Compounds Estrogen Receptor/ERR Endogenous Metabolite
    Cholesterol- 18O is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>-18O
  • HY-W127349

    Biochemical Assay Reagents Others
    Cholesterol n-Octanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caprylic acid. Cholesterol n-octanoate has various applications in the pharmaceutical industry, notably as a bioactive compound with potential research potential to improve a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    <em>Cholesterol</em> n-Octanoate
  • HY-W127528

    Biochemical Assay Reagents Endogenous Metabolite Others
    Cholesterol nervonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    <em>Cholesterol</em> nervonate
  • HY-130502

    cholesterol beta-epoxide

    Biochemical Assay Reagents Others
    Cholesterol 5beta,6beta-epoxide is an oxidative metabolite of cholesterol formed by free-radical and non-radical oxidation of cholesterol at the 5,6 double bond. Induces lactate dehydrogenase (LDH) release and apoptosis in macrophage-differentiated U937 cells. Cholesterol 5beta,6beta-epoxide has been found in human fatty streaks and advanced atherosclerotic lesions, but not in normal aortic tissue .
    <em>Cholesterol</em> 5beta,6beta-epoxide
  • HY-W010695S

    Isotope-Labeled Compounds Others
    Cholesterol stearate-d6 is the deuterium labeled Cholesterol stearate[1].
    <em>Cholesterol</em> stearate-d6
  • HY-111355S

    Isotope-Labeled Compounds Others
    Cholesterol sulfate sodium-d7 is the deuterium labeled Cholesterol sulfate sodium[1].
    <em>Cholesterol</em> sulfate-d7 sodium
  • HY-N0322S4

    Estrogen Receptor/ERR Endogenous Metabolite Metabolic Disease
    Cholesterol- 13C3 is the 13C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>-13C3
  • HY-N0322S2

    Isotope-Labeled Compounds Estrogen Receptor/ERR Endogenous Metabolite Metabolic Disease
    Cholesterol-d6-1 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>-d6-1
  • HY-N0322S3

    Estrogen Receptor/ERR Endogenous Metabolite Metabolic Disease
    Cholesterol- 13C5 is the 13C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>-13C5
  • HY-N0322S5

    Estrogen Receptor/ERR Endogenous Metabolite Metabolic Disease
    Cholesterol- 13C2 is the 13C labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
    <em>Cholesterol</em>-13C2
  • HY-156799

    Cytochrome P450 Others
    Cholesterol 24-hydroxylase-IN-2 is an inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), with the IC50 of 5.4 nM. Cholesterol 24-hydroxylase-IN-2 can be used in imaging of cholesterol 24-hydroxylase in mammals .
    <em>Cholesterol</em> 24-hydroxylase-IN-2
  • HY-P2848

    ChOx

    Endogenous Metabolite Others
    Cholesterol oxidase, Microorganism (ChOx) is a bacterial flavin oxidase containing FAD, commonly used in biochemical research. Cholesterol oxidase catalyzes the oxidation of the C(3)-OH group of cholesterol (and other sterols) to cholest-5-en-3-one and isomerizes it to cholest-4-en-3-one .
    <em>Cholesterol</em> oxidase, Microorganism
  • HY-W010800A

    cholesterol hydrogen succinate Tris salt; CHS-Tris

    Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis Cancer
    Cholesterol hemisuccinate Tris salt (CHS-Tris) is an ionizable anionic detergent that stabilizes large unilamellar vesicles. CHS-Tris and Lauryl Maltose Neopentyl Glycol (LMNG) or n-Dodecyl-β-D-Maltoside (DDM) are used together for the solubilization of membrane proteins while maintaining structural integrity and activity. Cholesteryl succinate also reportedly exhibits antiproliferative activity.
    <em>Cholesterol</em> hemisuccinate Tris salt
  • HY-N2339
    Cholesteryl behenate
    1 Publications Verification

    Cholesteryl docosanoate; cholesterol behenate

    Endogenous Metabolite Metabolic Disease
    Cholesteryl behenate is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.
    Cholesteryl behenate
  • HY-N2338

    Cholesteryl myristate; Cholesteryl tetradecanoate

    nAChR GABA Receptor Potassium Channel Endogenous Metabolite Cancer
    Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.
    <em>Cholesterol</em> myristate
  • HY-133971S

    Isotope-Labeled Compounds Others
    Cholesterol-5α,6α-epoxide-d7 is deuterium labeled Cholesterol-5α,6α-epoxide.
    <em>Cholesterol</em>-5α,6α-epoxide-d7
  • HY-W440715

    Liposome Others
    Cholesterol-PEG-Folate, MW 2000 is an excipient and can be used for the preparation of folate-conjugated PEG-liposomes .
    <em>Cholesterol</em>-PEG-Folate, MW 2000
  • HY-133971

    5α,6α-Epoxycholesterol

    Biochemical Assay Reagents Others
    Cholesterol-5α,6α-epoxide is an epoxide derivative of cholesterol formed by the enzymatic oxidation of cholesterol in the liver and other tissues. Cholesterol-5α,6α-epoxide has unique chemical properties that make it an important intermediate in the biosynthesis of bile acids, which play a key role in the digestion and absorption of dietary fats. It also has a potential physiological role in regulating cholesterol metabolism and transport, although its biological function is not fully understood.
    <em>Cholesterol</em> 5α,6α-epoxide
  • HY-W010800

    cholesterol hydrogen succinate

    Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis Cancer
    Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth .
    Cholesteryl hemisuccinate
  • HY-D1621

    Fluorescent Dye Others
    C-12 NBD cholesterol is a cholesterol derivative with a hydrophilic fluorophore tag (NBD: Ex=465 nm, Em=535 nm). C-12 NBD cholesterol can be used to study the utilization and metabolism of cholesterol .
    3-NBD-C12 <em>Cholesterol</em>
  • HY-139407

    3-Dodecanoyl-NBD-cholesterol

    Fluorescent Dye Others
    3-C12-NBD-cholesterol is a fluorescent cholesterol analog that can be used for measuring membrane and intracellular trafficking dynamics .
    3-C12-NBD-<em>cholesterol</em>
  • HY-151705

    Liposome Metabolic Disease
    Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .
    Alkyne <em>Cholesterol</em>
  • HY-D2263

    Fluorescent Dye Others
    BODIPY-cholesterol conjugate-3 (compound 7) is a cholesterol analogue with a fluorescent BODIPY group. BODIPY-cholesterol conjugate-3 can be used to simultaneously visualize multiple cholesterol pools in cells, as it is primarily localized to the plasma membrane .
    BODIPY-<em>cholesterol</em> conjugate-3
  • HY-D1595

    Fluorescent Dye Others
    BODIPY FL Cholesterol is a green fluorescent, lipophilic probe. BODIPY FL Cholesterol can be used for the research of lipid transport processes and lipid-protein interactions .
    BODIPY FL <em>Cholesterol</em>
  • HY-123349

    Drug Metabolite Cardiovascular Disease
    5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM .
    5α-Hydroxy-6-keto <em>cholesterol</em>
  • HY-156197

    Liposome Estrogen Receptor/ERR Endogenous Metabolite Bacterial Cancer
    Biotin-cholesterol is a biotinylated form of Cholesterol (HY-N0322). Biotin-cholesterol can be used in the synthesis of biotin-conjugated liposomes and micelles for drug delivery .
    Biotin-<em>cholesterol</em>
  • HY-125746
    BODIPY-Cholesterol
    3 Publications Verification

    Fluorescent Dye Others
    BODIPY-cholesterol is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 480/508 nm) .
    BODIPY-<em>Cholesterol</em>
  • HY-D2261

    Fluorescent Dye Metabolic Disease
    BODIPY-cholesterol conjugate-1 (compound 5) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-1 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors . (λex 541 nm, λem 615 nm).
    BODIPY-<em>cholesterol</em> conjugate-1
  • HY-D2262

    Fluorescent Dye Metabolic Disease
    BODIPY-cholesterol conjugate-2 (compound 6) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-2 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors. (λex=589 nm, λem=638 nm) .
    BODIPY-<em>cholesterol</em> conjugate-2
  • HY-113342S

    Endogenous Metabolite Isotope-Labeled Compounds Others
    7-Keto Cholesterol-d7 is the deuterium labeled 7-Keto Cholesterol[1].
    7-Keto <em>Cholesterol</em>-d7
  • HY-131682

    3-Hexanoyl-NBD-cholesterol

    Others Fluorescent Dye Others
    3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking .
    3-C6-NBD-<em>cholesterol</em>
  • HY-141862

    Influenza Virus Infection
    Zanamivir–cholesterol conjugate is a long-acting neuraminidase inhibitor with potent efficacy against drug-resistant influenza viruses.
    Zanamivir-<em>Cholesterol</em> Conjugate
  • HY-143367S

    Isotope-Labeled Compounds Others
    27-Hydroxy cholesterol-d6 is deuterium labeled 27-Hydroxy cholesterol.
    27-Hydroxy <em>cholesterol</em>-d6
  • HY-160578

    N-Cholesteryl succinyl glucosamine

    Liposome Others
    Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs) .
    Glucosamine <em>Cholesterol</em>
  • HY-121795

    HMG-CoA Reductase (HMGCR) Cardiovascular Disease
    Pravastatin lactone is a potent HMG-CoA inhibitor. Pravastatin Lactone is a metabolite of pravastatin. Pravastatin lactone reduces blood cholesterol levels by inhibiting cholesterol synthesis .
    Pravastatin lactone
  • HY-149664

    DC-Chol

    Liposome Cancer
    3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .
    3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]<em>cholesterol</em>

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