Search Result
Results for "
ionizable lipid
" in MedChemExpress (MCE) Product Catalog:
45
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-160439
-
|
Liposome
|
Others
|
Ionizable lipid-2 (compound 1) is an ionizable lipid used for nucleic acid delivery and construct lipid nanoparticles (LNPs) .
|
-
-
- HY-156630
-
|
Liposome
|
Others
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
-
-
- HY-148648
-
|
Liposome
|
Others
|
Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles .
|
-
-
- HY-156630A
-
|
Liposome
|
Others
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
-
-
- HY-W440753
-
|
Liposome
|
Others
|
BP Lipid 114 is an ethanolamine ionizable lipid (CN113387825A) .
|
-
-
- HY-W440779
-
|
Liposome
|
Metabolic Disease
|
BP Lipid 135 is a cationieally ionizable lipid. BP Lipid 135 can be used to prepare lipid nanoparticles (LNP) (WO2022218503A1) .
|
-
-
- HY-142995
-
|
Liposome
|
Others
|
DODAP (hydrochloride) is an ionizable lipid. DODAP (hydrochloride) has the potential for the research of gene delivery .
|
-
-
- HY-160553
-
|
Liposome
|
Others
|
9322-O16B, an ionizable cationic lipid, is used for LNP generation .
|
-
-
- HY-151507
-
|
Liposome
|
Others
|
306Oi10 is a branched-chain ionizable lipidoid that can be used for constructing lipid nanoparticles (LNPs) for the delivery of messenger RNA .
|
-
-
- HY-130751
-
|
Liposome
|
Inflammation/Immunology
|
DODAP is a cationic lipid. The ionizable lipid DODAP is the lipid component of liposomes (pKa = 5.59 in TNS binding tests). DODAP can be used for siRNA encapsulation and in vitro and in vivo delivery of immunostimulated chemotherapeutic active molecules .
|
-
-
- HY-154974
-
|
Liposome
|
Cancer
|
LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model .
|
-
-
- HY-160552
-
|
Liposome
|
Others
|
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .
|
-
-
- HY-145405
-
C12-200
5 Publications Verification
|
Liposome
|
Others
|
C12-200 is an ionizable cationic lipid and auxiliary lipid. C12-200 is commonly used for mRNA delivery. Administration of human erythropoietin (EPO) mRNA or factor VII siRNA increased and decreased serum factor VII levels, respectively, in LNPs mice containing C12-200 .
|
-
-
- HY-147332
-
|
Liposome
|
Neurological Disease
|
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
|
-
-
- HY-150116
-
|
Liposome
|
Others
|
Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
-
- HY-150115
-
|
Liposome
|
Others
|
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
-
- HY-153378
-
|
Liposome
|
Others
|
Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
-
- HY-150117
-
|
Liposome
|
Others
|
Lipid 6 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
-
- HY-150118
-
|
Liposome
|
Others
|
Lipid 8 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
-
- HY-153377
-
-
-
- HY-134782
-
|
Liposome
|
Others
|
OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
-
- HY-153186
-
|
Liposome
|
Others
|
LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).
|
-
-
- HY-153375
-
|
Liposome
|
Others
|
LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .
|
-
-
- HY-153376
-
|
Liposome
|
Others
|
LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .
|
-
-
- HY-153373
-
|
Liposome
|
Others
|
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).
|
-
-
- HY-145739
-
-
-
- HY-160705
-
|
Liposome
|
|
PNI 132, an ionizable lipid derived from the patent WO2020252589A, is useful in the formulation of lipid nanoparticles.
|
-
-
- HY-145796
-
|
Liposome
|
Others
|
503O13 is a degradable ionizable lipid for siRNA delivery.
|
-
-
- HY-112757
-
DLinDMA
1 Publications Verification
|
Liposome
|
Others
|
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
|
-
-
- HY-W590532
-
|
Liposome
|
Others
|
306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).
|
-
-
- HY-149156
-
|
Liposome
|
Cancer
|
Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
|
-
-
- HY-156985
-
|
Isotope-Labeled Compounds
Liposome
|
Others
|
Lipid AX4 is an ionizable cationic lipid with the pKa of 6.89, and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .
|
-
-
- HY-46759
-
|
Liposome
|
Infection
|
Genevant CL1 is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2].
|
-
-
- HY-149167
-
|
Liposome
Biochemical Assay Reagents
|
Others
|
mRNA-Encapsulating Lipid Excipient 1 (Compound 2) is a Thiocarbamate-Based Ionizable Lipid. mRNA-Encapsulating Lipid Excipient 1 can be used as an excipient in mRNA-encapsulating lipid nanoparticle .
|
-
-
- HY-153372
-
|
Liposome
|
Others
|
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
|
-
-
- HY-46759A
-
|
Liposome
|
Infection
|
Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .
|
-
-
- HY-W590548
-
|
Liposome
|
Others
|
ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA .
|
-
-
- HY-148842
-
|
Liposome
|
Others
|
C14-4 is an ionizable lipid for lipid nanoparticles (LNPs) formulation. C14-4 was identified for its potent transfection and low cytotoxicity.
|
-
-
- HY-W590531
-
-
-
- HY-156857
-
-
-
- HY-151511
-
|
Liposome
|
Cancer
|
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
|
-
-
- HY-W590678
-
|
Liposome
|
Others
|
SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.
|
-
-
- HY-112251
-
D-Lin-MC3-DMA
Maximum Cited Publications
52 Publications Verification
|
Liposome
|
Cancer
|
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
-
- HY-145795
-
|
Liposome
|
Others
|
OF-02 is an alkenyl amino alcohol (AAA) ionizable lipid for highly potent in vivo mRNA delivery.
|
-
-
- HY-148049
-
|
Liposome
|
Others
|
TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .
|
-
-
- HY-134781
-
CKK-E12
1 Publications Verification
|
Liposome
|
Others
|
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
|
-
-
- HY-160580
-
|
Liposome
|
Others
|
G1-OC2-K3-E10 is an ionizable lipid, and can be used for delivery of mRNA in lipid nanoparticles (LNPs) .
|
-
-
- HY-156936
-
|
Liposome
|
Others
|
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
|
-
-
- HY-W598178
-
|
Liposome
|
Others
|
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
|
-
-
- HY-153737
-
|
Liposome
|
Others
|
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
|
-
- HY-112772A
-
|
Liposome
|
Others
|
98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA–delivery to the liver.
|
-
- HY-148855
-
|
Liposome
|
Others
|
OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA .
|
-
- HY-142654
-
|
Liposome
|
Others
|
ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .
|
-
- HY-W590681
-
|
Liposome
|
Others
|
113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
- HY-W590679
-
|
Liposome
|
Others
|
113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
- HY-151512
-
-
- HY-160852
-
|
Liposome
|
Inflammation/Immunology
|
YSK 12C4 is an ionizable cationic lipid primarily used to enhance siRNA cellular delivery via multifunctional envelope-type nanodevices (MEND). YSK 12C4 promotes siRNA uptake and endosomal escape, effectively silencing genes in human immune cell lines .
|
-
- HY-157252
-
|
Liposome
|
Cancer
|
CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
|
-
- HY-112251S
-
|
Isotope-Labeled Compounds
|
Others
|
D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle[1][2].
|
-
- HY-145798
-
|
Liposome
|
Others
|
N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 (HY-148049). TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-156630
-
|
Drug Delivery
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
-
- HY-148648
-
|
Drug Delivery
|
Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles .
|
-
- HY-156630A
-
|
Drug Delivery
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
-
- HY-W440753
-
|
Drug Delivery
|
BP Lipid 114 is an ethanolamine ionizable lipid (CN113387825A) .
|
-
- HY-W440779
-
|
Drug Delivery
|
BP Lipid 135 is a cationieally ionizable lipid. BP Lipid 135 can be used to prepare lipid nanoparticles (LNP) (WO2022218503A1) .
|
-
- HY-142995
-
|
Drug Delivery
|
DODAP (hydrochloride) is an ionizable lipid. DODAP (hydrochloride) has the potential for the research of gene delivery .
|
-
- HY-151507
-
|
Drug Delivery
|
306Oi10 is a branched-chain ionizable lipidoid that can be used for constructing lipid nanoparticles (LNPs) for the delivery of messenger RNA .
|
-
- HY-130751
-
|
Drug Delivery
|
DODAP is a cationic lipid. The ionizable lipid DODAP is the lipid component of liposomes (pKa = 5.59 in TNS binding tests). DODAP can be used for siRNA encapsulation and in vitro and in vivo delivery of immunostimulated chemotherapeutic active molecules .
|
-
- HY-145405
-
C12-200
5 Publications Verification
|
Drug Delivery
|
C12-200 is an ionizable cationic lipid and auxiliary lipid. C12-200 is commonly used for mRNA delivery. Administration of human erythropoietin (EPO) mRNA or factor VII siRNA increased and decreased serum factor VII levels, respectively, in LNPs mice containing C12-200 .
|
-
- HY-147332
-
|
Drug Delivery
|
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
|
-
- HY-150116
-
|
Drug Delivery
|
Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-150115
-
|
Drug Delivery
|
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-153378
-
|
Drug Delivery
|
Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-150117
-
|
Drug Delivery
|
Lipid 6 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-150118
-
|
Drug Delivery
|
Lipid 8 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-153377
-
|
Drug Delivery
|
Lipid 14 is a potent ionizable lipid and can be used to synthesize lipid nanoparticles (LNPs) .
|
-
- HY-134782
-
|
Drug Delivery
|
OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-153186
-
|
Drug Delivery
|
LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-153375
-
|
Drug Delivery
|
LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .
|
-
- HY-153376
-
|
Drug Delivery
|
LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .
|
-
- HY-153373
-
|
Drug Delivery
|
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).
|
-
- HY-145739
-
-
- HY-145796
-
|
Drug Delivery
|
503O13 is a degradable ionizable lipid for siRNA delivery.
|
-
- HY-112757
-
DLinDMA
1 Publications Verification
|
Drug Delivery
|
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
|
-
- HY-W590532
-
|
Drug Delivery
|
306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).
|
-
- HY-149156
-
|
Drug Delivery
|
Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
|
-
- HY-46759
-
|
Drug Delivery
|
Genevant CL1 is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2].
|
-
- HY-149167
-
|
Drug Delivery
|
mRNA-Encapsulating Lipid Excipient 1 (Compound 2) is a Thiocarbamate-Based Ionizable Lipid. mRNA-Encapsulating Lipid Excipient 1 can be used as an excipient in mRNA-encapsulating lipid nanoparticle .
|
-
- HY-153372
-
|
Drug Delivery
|
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
|
-
- HY-46759A
-
|
Drug Delivery
|
Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .
|
-
- HY-148842
-
|
Drug Delivery
|
C14-4 is an ionizable lipid for lipid nanoparticles (LNPs) formulation. C14-4 was identified for its potent transfection and low cytotoxicity.
|
-
- HY-156857
-
|
Drug Delivery
|
PPZ-A10 is a ionizable lipid that delivered mRNA preferentially to liver and spleen immune cells.
|
-
- HY-151511
-
|
Drug Delivery
|
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
|
-
- HY-W590678
-
|
Drug Delivery
|
SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.
|
-
- HY-112251
-
D-Lin-MC3-DMA
Maximum Cited Publications
52 Publications Verification
|
Drug Delivery
|
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
- HY-145795
-
|
Drug Delivery
|
OF-02 is an alkenyl amino alcohol (AAA) ionizable lipid for highly potent in vivo mRNA delivery.
|
-
- HY-148049
-
|
Drug Delivery
|
TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .
|
-
- HY-134781
-
CKK-E12
1 Publications Verification
|
Drug Delivery
|
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
|
-
- HY-153737
-
|
Drug Delivery
|
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
|
-
- HY-112772A
-
|
Drug Delivery
|
98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA–delivery to the liver.
|
-
- HY-148855
-
|
Drug Delivery
|
OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA .
|
-
- HY-142654
-
|
Drug Delivery
|
ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .
|
-
- HY-151512
-
|
Drug Delivery
|
A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .
|
-
- HY-157252
-
|
Drug Delivery
|
CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
|
-
- HY-145798
-
|
Drug Delivery
|
N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 (HY-148049). TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W141932
-
Stearoylglycine; N-Octadecanoylglycine
|
Peptides
|
Others
|
N-stearoylglycine is a lipid and has a small ionizable polar headgroup whose charge is pH dependent and whose amide moiety can form H-bonded network between adjacent molecules in ordered films .
|
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-112251S
-
|
D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle[1][2].
|
-
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