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Results for "

nicotinic

" in MedChemExpress (MCE) Product Catalog:

247

Inhibitors & Agonists

1

Screening Libraries

2

Biochemical Assay Reagents

28

Peptides

44

Natural
Products

5

Recombinant Proteins

26

Isotope-Labeled Compounds

2

Antibodies

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Cat. No. Compare Product Name Species Source
  • HY-P72140
    CHRNA1 Protein, Human (His-Trx)

    Acetylcholine receptor subunit alpha; ACHA_HUMAN; AChR; ACHRA; ACHRD; CHNRA; Cholinergic receptor nicotinic alpha 1 subunit; Cholinergic receptor nicotinic alpha polypeptide 1; Cholinergic receptor; nicotinic; alpha polypeptide 1 muscle; ; Chrna1; CMS1A; CMS1B; CMS2A; FCCMS; nicotinic cholinergic receptor alpha 1; SCCMS; Schizophrenia neurophysiologic defect candidate

    		 Human E. coli
    The CHRNA1 Protein undergoes a substantial conformational shift upon acetylcholine binding, influencing all subunits and leading to the activation of an ion-conducting channel. Yet, the acetylcholine receptor alpha subunit of CHRNA1 can be non-functional in certain cases, underscoring the need to comprehend the factors governing its functionality and integration into fully operational acetylcholine-gated cation-selective channels. CHRNA1 Protein, Human (His-Trx) is the recombinant human-derived CHRNA1 protein, expressed by E. coli , with N-Trx, N-6*His labeled tag. The total length of CHRNA1 Protein, Human (His-Trx) is 235 a.a., with molecular weight of ~44.1 kDa.
  • HY-P72139
    CHRNA1 Protein, Human (His)

    Acetylcholine receptor subunit alpha; ACHA_HUMAN; AChR; ACHRA; ACHRD; CHNRA; Cholinergic receptor nicotinic alpha 1 subunit; Cholinergic receptor nicotinic alpha polypeptide 1; Cholinergic receptor; nicotinic; alpha polypeptide 1 muscle; ; Chrna1; CMS1A; CMS1B; CMS2A; FCCMS; nicotinic cholinergic receptor alpha 1; SCCMS; Schizophrenia neurophysiologic defect candidate

    		 Human E. coli
    The CHRNA1 Protein undergoes a substantial conformational shift upon acetylcholine binding, influencing all subunits and leading to the activation of an ion-conducting channel. Yet, the acetylcholine receptor alpha subunit of CHRNA1 can be non-functional in certain cases, underscoring the need to comprehend the factors governing its functionality and integration into fully operational acetylcholine-gated cation-selective channels. CHRNA1 Protein, Human (His) is the recombinant human-derived CHRNA1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CHRNA1 Protein, Human (His) is 235 a.a., with molecular weight of ~31.1 kDa.
  • HY-P702313
    HCAR2 Protein, Human (Cell-Free, His)

    Hydroxycarboxylic acid receptor 2; G-protein coupled receptor 109A; G-protein coupled receptor HM74A; Niacin receptor 1; nicotinic acid receptor

    		 Human E. coli Cell-free
    HCAR2 protein, a high-affinity receptor for nicotinic acid and (D)-beta-hydroxybutyrate, induces increased adiponectin secretion and reduced lipolysis through G(i)-protein-mediated adenylyl cyclase inhibition. This requires nicotinic acid doses exceeding typical dietary levels. HCAR2 also mediates nicotinic acid-induced apoptosis in neutrophils. Upon nicotinic acid activation, reduced cAMP levels potentially influence cAMP-dependent protein kinase A activity and target protein phosphorylation, leading to neutrophil apoptosis. Relative potency for displacing nicotinic acid binding: 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide. HCAR2 Protein, Human (Cell-Free, His) is the recombinant human-derived HCAR2 protein, expressed by E. coli Cell-free, with C-6*His labeled tag. The total length of HCAR2 Protein, Human (Cell-Free, His) is 363 a.a., with molecular weight of 42.7 kDa.
  • HY-P75941
    NMNAT1 Protein, Human (sf9, His)

    Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1; NMNAT1; NMNAT

    		 Human Sf9 insect cells
    The NMNAT1 protein catalyzes the formation of NAD(+) from NMN and ATP and efficiently uses deamidated NaMN and triazofurane monophosphate as substrates. NMNAT1 Protein, Human (sf9, His) is the recombinant human-derived NMNAT1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of NMNAT1 Protein, Human (sf9, His) is 279 a.a., with molecular weight of ~34 kDa.
  • HY-P72144
    CHRNA3 Protein, Human (His-SUMO)

    ACHA3_HUMAN; AChR; Cholinergic receptor neuronal nicotinic alpha polypeptide 3; Cholinergic receptor nicotinic alpha 3; Cholinergic receptor nicotinic alpha polypeptide 3; CHRNA 3; CHRNA3; LNCR2; MGC104879; NACHRA 3; NACHRA3; Neuronal acetylcholine receptor protein alpha 3 chain precursor; Neuronal acetylcholine receptor subunit alpha 3; Neuronal acetylcholine receptor subunit alpha-3; Neuronal nicotinic acetylcholine receptor alpha 3 subunit; PAOD2

    		 Human E. coli
    CHRNA3 Protein, a critical contributor to collagen fibrillogenesis, regulates the rate of fibril formation and influences the assembly and organization of collagen fibrils. Binding to both type I and type II collagen, CHRNA3 plays a pivotal role in shaping the structural integrity of the extracellular matrix. CHRNA3 Protein, Human (His-SUMO) is the recombinant human-derived CHRNA3 protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag. The total length of CHRNA3 Protein, Human (His-SUMO) is 209 a.a., with molecular weight of ~44.6 kDa.

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