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Results for "

thrombospondin

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

21

Peptides

11

Recombinant Proteins

3

Antibodies

Cat. No. Product Name Target Research Area
  • HY-P0144
    Thrombospondin-1 (1016-1023) (human, bovine, mouse)

    		Apoptosis Inflammation/Immunology
    Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide .
  • HY-P0299
    LSKL, Inhibitor of Thrombospondin (TSP-1)
    Maximum Cited Publications
    10 Publications Verification

    		 TGF-β Receptor Cancer
    LSKL, Inhibitor of Thrombospondin (TSP-1) is a latency-associated protein (LAP)-TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH). LSKL, Inhibitor of Thrombospondin (TSP-1) can readily crosse the blood-brain barrier .
  • HY-P0299A
    LSKL, Inhibitor of Thrombospondin (TSP-1) (TFA)
    Maximum Cited Publications
    10 Publications Verification

    		 TGF-β Receptor Cancer
    LSKL, Inhibitor of Thrombospondin (TSP-1) TFA is a latency-associated protein (LAP)-TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) TFA inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) TFA suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH). LSKL, Inhibitor of Thrombospondin (TSP-1) TFA can readily crosse the blood-brain barrier .
  • HY-P3968
    Thrombospondin-1 (1016-1021) (human, bovine, mouse)

    		Peptides Others
    Thrombospondin-1 (1016-1021) (human, bovine, mouse), a Thrombospondin-1-derived peptide, is a truncated peptide devoid of CD47-binding activity .
  • HY-P5322
    Thrombospondin (TSP-1)-derived CD36 binding motif

    		Peptides Others
    Thrombospondin (TSP-1)-derived CD36 binding motif is a biological active peptide. (This peptide is derived from thrombospondin and represents a binding motif responsible for thrombospondin-CD36 interaction. It is cyclized through a disulfide bond. Thrombospondin is a matrix-bound glycoprotein involved in cancer metastasis, tumor adhesion, and angiogenesis. This peptide has been shown to competitively inhibit platelet aggregation and tumor metastasis.)
  • HY-P3972
    H-ILE-ARG-VAL-VAL-MET-OH

    		Peptides Cancer
    H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide from C7 with a domain that supports cell attachment. H-ILE-ARG-VAL-VAL-MET-OH is also the sequence fragment that binds to the thrombospondin-1 (TS1) receptor .
  • HY-P4003
    Adamtsostatin 16

    		ADAMTS Cardiovascular Disease
    Adamtsostatin 16 is an anti-angiogenic 17-amino acid peptide containing type I thrombospondin motifs .
  • HY-P0301A
    SLLK, Control Peptide for TSP1 Inhibitor(TFA)

    		Peptides Cancer
    SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor.
  • HY-P4016
    Semastatin 5A.2

    		Peptides Cardiovascular Disease
    Semastatin 5A.2 is an anti-angiogenic 19-amino acid peptides that are derived from proteins containing type I thrombospondin motifs .
  • HY-P4017
    Semastatin 5A.1

    		Peptides Cardiovascular Disease
    Semastatin 5A.1 is an anti-angiogenic 19-amino acid peptides that are derived from proteins containing type I thrombospondin motifs .
  • HY-13545
    ABT-510

    		Apoptosis Inflammation/Immunology Cancer
    ABT-510 is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer. ABT-510 also reduces angiogenesis and inflammatory responses in a murine model of inflammatory bowel disease. ABT-510 can be used in studies of cancer (particularly epithelial ovarian cancer) and inflammatory bowel disease (IBD) .
  • HY-13545B
    ABT-510 acetate

    		Apoptosis Inflammation/Immunology Cancer
    ABT-510 acetate is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer. ABT-510 acetate also reduces angiogenesis and inflammatory responses in a murine model of inflammatory bowel disease. ABT-510 acetate can be used in studies of cancer (particularly epithelial ovarian cancer) and inflammatory bowel disease (IBD) .
  • HY-P4002
    Adamtsostatin 18

    		ADAMTS Cancer
    Adamtsostatin 18 is an anti-angiogenic peptide derived from proteins containing type I thrombospondin motifs. Adamtsostatin 18 inhibits cell migration and proliferation .
  • HY-P3996
    Properdistatin

    		Peptides Cancer
    Properdistatin is a peptide derived from the thrombospondin 1 (TSP-1) domain of properdin. Properdistatin inhibits angiogenesis and improves vascular function. Properdistatin has the potential for the research of melanoma .
  • HY-P3974
    Semastatin-5B

    		Peptides Cardiovascular Disease
    Semastatin-5B is an anti-angiogenic 17-amino acid peptide. Semastatin-5B can be derived from proteins containing type I thrombospondin motifs .
  • HY-P5349
    4N1K peptide

    		Peptides Others
    4N1K peptide is a biological active peptide. (4N1K-peptide (KRFYVVMWKK), which is derived from thrombospondins has anti-cancer activities in several cancers)
  • HY-P10184
    CD36 Peptide P (93-110), Cys conjugated

    		Peptides Inflammation/Immunology
    CD36 Peptide P (93-110), Cys conjugated is a Cys labelled CD36 Peptide, and can block binding of CD36 to immobilized thrombospondin and partially inhibited collagen-induced platelet aggregation .
  • HY-P3970
    KRFK

    		TGF-β Receptor Inflammation/Immunology
    KRFK, a peptide derived from TSP-1, can activate TGF-β. KRFK promotes TGF-β-mediated signaling and its downstream role, independent of thrombospondin (TSP) receptors such as CD47 and CD36. KRFK can be used for chronic ocular surface inflammatory disorders reseach .
  • HY-P3970A
    KRFK TFA
    2 Publications Verification

    		 TGF-β Receptor Inflammation/Immunology
    KRFK TFA, a peptide derived from TSP-1, can activate TGF-β. KRFK TFA promotes TGF-β-mediated signaling and its downstream role, independent of thrombospondin (TSP) receptors such as CD47 and CD36. KRFK TFA can be used for chronic ocular surface inflammatory disorders reseach .
  • HY-P5419
    WAAG-3R

    		Peptides Others
    WAAG-3R is a biological active peptide. (Aggrecanases belong to the ADAMTS (A disintegrin and metalloprotease with thrombospondin motif) family of proteases. Aggrecanases cleave aggrecan, the major structural component of cartilage. Aggrecanase-1 (ADAMTS-4) is a major aggrecanase in human osteoarthritic cartilage. This FRET peptide was used in an ADAMTS-4 (Aggrecanase-1) assay. Ex/Em = 340/420 nm.)
  • HY-P5419A
    WAAG-3R TFA

    		Peptides Others
    WAAG-3R TFA is a biological active peptide. (Aggrecanases belong to the ADAMTS (A disintegrin and metalloprotease with thrombospondin motif) family of proteases. Aggrecanases cleave aggrecan, the major structural component of cartilage. Aggrecanase-1 (ADAMTS-4) is a major aggrecanase in human osteoarthritic cartilage. This FRET peptide was used in an ADAMTS-4 (Aggrecanase-1) assay. Ex/Em = 340/420 nm.) .

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