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urticarial

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By Targets:	Akt (1) Cytochrome P450 (2) Drug Metabolite (2) Histamine Receptor (11) Isotope-Labeled Compounds (3) mTOR (1) PI3K (1)
By Research Areas:	Cancer (2) Endocrinology (1) Inflammation/Immunology (12) Neurological Disease (3)

15

Inhibitors & Agonists

1

Inhibitory Antibodies

4

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Fexofenadine hydrochloride 4 Publications Verification MDL-16455 hydrochloride; Terfenadine carboxylate hydrochloride	Histamine Receptor	Inflammation/Immunology
Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H₁ receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research .

Fexofenadine 4 Publications Verification MDL-16455; Terfenadine carboxylate	Histamine Receptor	Inflammation/Immunology
Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .

Mizolastine	Histamine Receptor	Inflammation/Immunology
Mizolastine is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial .

meta-Fexofenadine meta-MDL-16455; meta-Terfenadine carboxylate	Drug Metabolite	Inflammation/Immunology
meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine . Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .

Fexofenadine-d3-1 MDL-16455-d₃-1; Terfenadine carboxylate-d₃-1	Histamine Receptor Isotope-Labeled Compounds	Inflammation/Immunology
Fexofenadine-d₃-1 fumarate is deuterated labeled Fexofenadine (HY-B0801). Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research .

Mizolastine dihydrochloride	Histamine Receptor	Inflammation/Immunology
Mizolastine dihydrochloride is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine dihydrochloride effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine dihydrochloride can be used in studies of allergic rhinitis and chronic idiopathic urticarial .

Mizolastine (Standard)	Histamine Receptor	Inflammation/Immunology
Mizolastine (Standard) is the analytical standard of Mizolastine. This product is intended for research and analytical applications. Mizolastine is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial .

Meta-Fexofenadine-d6 meta-MDL-16455-d₆; meta-Terfenadine carboxylate-d₆	Isotope-Labeled Compounds	Inflammation/Immunology
Meta-Fexofenadine-d₆ is the deuterium labeled meta-Fexofenadine. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine[1]. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial[2].

Fexofenadine Impurity F	Drug Metabolite	Others
Fexofenadine Impurity F is the impurity of Fexofenadine. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial .

Fexofenadine-d10 hydrochloride MDL-16455-d₁₀ hydrochloride; Terfenadine carboxylate-d₁₀ hydrochloride	Isotope-Labeled Compounds Histamine Receptor	Inflammation/Immunology Endocrinology
Fexofenadine-d₁₀ (hydrochloride) is deuterium labeled Fexofenadine (hydrochloride). Fexofenadine hydrochloride (MDL-16455 hydrochloride), a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial (person aged ≥16 years)[1].

Fexofenadine-d3 MDL-16455-d₃; Terfenadine carboxylate-d₃	Histamine Receptor	Inflammation/Immunology
Fexofenadine-d₃ is the deuterium labeled Fexofenadine[1]. Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research[2][3][4].

Fexofenadine hydrochloride (Standard) MDL-16455 hydrochloride (Standard); Terfenadine carboxylate hydrochloride (Standard)	Histamine Receptor	Inflammation/Immunology
Fexofenadine (hydrochloride) (Standard) is the analytical standard of Fexofenadine (hydrochloride). This product is intended for research and analytical applications. Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H₁ receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research .

Doxepin	mTOR PI3K Akt	Neurological Disease
Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant. Doxepin has therapeutic effects in atopic dermatitis，chronic urticarial，can improve cognitive processes， protect central nervous system. Doxepin has also been proposed as a protective factor against oxidative stress .

Doxepin Hydrochloride 4 Publications Verification	Histamine Receptor Cytochrome P450	Neurological Disease Cancer
Doxepin hydrochloride is an orally active tricyclic antidepressant agent. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2 . Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant . . Doxepin has therapeutic effects in atopic dermatitis，chronic urticarial，can improve cognitive processes， protect central nervous system . . Doxepin has also been proposed as a protective factor against oxidative stress . .

Doxepin Hydrochloride (Standard)	Histamine Receptor Cytochrome P450	Neurological Disease Cancer
Doxepin (Hydrochloride) (Standard) is the analytical standard of Doxepin (Hydrochloride). This product is intended for research and analytical applications. Doxepin hydrochloride is an orally active tricyclic antidepressant agent. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2 . Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant . . Doxepin has therapeutic effects in atopic dermatitis，chronic urticarial，can improve cognitive processes， protect central nervous system . . Doxepin has also been proposed as a protective factor against oxidative stress . .

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